ID | 19477 |
Eprint ID | 19477
|
FullText URL | |
Title Alternative | Experimental studies on Japanese B Encephalitis with radioactive P(32). 2. Nucleic acid metabolism, investigated by Schmidt & Thanhauser's method, in lung, spleen and kidney of the mouse infected with Japanese B Encephalitis
|
Author |
Uchida, Yutaka
|
Abstract | Somewhat detailed knowledge was obtained on the nucleic acid metabolism in long, spleen and kidney of the infected mouse P(32) was used as the tracer and was injected to each mouse intraperitoneally various hours after the intracerebral inoculation of the virus. 6 and 24 hours after the injection of P(32) the organs were collected and fractionated by Schmidt-Thanhauser's method into RNA-phosphoprotein fraction and DNA fraction, which were then examined on their radioactivities. Just at the incubation stage or the visceral phase of Japanese B encephalitis the organs, lung, spleen and kidney, of the mouse proved to have high radioactivities, both in their RNA-phosphoprotein fractions and DNA fractions. It is interesting to note that the radioactivity in DNA fraction was observed to increase rather late in the incubation stage while the other appeared from the first of that stage on. The fact that in case of spleen higher radiotivity of RNA-phosphoprotein fraction than that of DNA fraction was observed should further be pointed out. In contrast to this, the high radioactivities in acidsoluble fractions also observed at the mcnbation stage remained unaltered even at the acme stage of the disease.
|
Published Date | 1956-05-31
|
Publication Title |
岡山医学会雑誌
|
Publication Title Alternative | Journal of Okayama Medical Association
|
Volume | volume68
|
Issue | issue5
|
Publisher | 岡山医学会
|
Publisher Alternative | Okayama Medical Association
|
Start Page | 341
|
End Page | 348
|
ISSN | 0030-1558
|
NCID | AN00032489
|
Content Type |
Journal Article
|
Official Url | https://www.jstage.jst.go.jp/article/joma1947/68/5/68_5_341/_article/-char/ja/
|
Related Url | http://www.okayama-u.ac.jp/user/oma/
|
language |
Japanese
|
Copyright Holders | 岡山医学会
|
File Version | publisher
|
Refereed |
True
|
Eprints Journal Name | joma
|