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Title Alternative The Birth of a Satirical Writer: Jonathan Swift’s Thought in His Early Years
FullText URL olj_67_1_1_29.pdf
Author Kishimoto, Hiroshi|
Publication Title Okayama Law Journal
Published Date 2017-08-31
Volume volume67
Issue issue1
Start Page 1
End Page 29
ISSN 0386-3050
language Japanese
File Version publisher
NAID 120006343749
FullText URL Org_Lett_19_5_1092.pdf
Author Iwasaki, Masayuki| Miki, Natsumi| Tsuchiya, Yuta| Nakajima, Kiyohiko| Nishihara, Yasushi|
Note This is an Accepted Manuscript of an article published by American Chemical Society|
Published Date 2017-02-17
Publication Title Organic Letters
Volume volume19
Issue issue5
Publisher American Chemical Society
Start Page 1092
End Page 1095
ISSN 1523-7060
NCID AA11347843
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 28211695
DOI 10.1021/acs.orglett.7b00116
Web of Science KeyUT 000395726100032
Related Url https://doi.org/10.1021/acs.orglett.7b00116
FullText URL K0005304 other1.pdf
Author Igawa, Takuro| Sato, Yasuharu| Takata, Katsuyoshi| Iwaki, Noriko| Tanaka, Takehiro| Asano, Naoko| Maeda, Yoshinobu| Orita, Yorihisa| Nakamura, Naoya| Nakamura, Shigeo| Yoshino, Tadashi|
Keywords Cyclin D2 CD5 Diffuse large B-cell lymphoma
Note 学位審査副論文|
Published Date 2013-05-15
Publication Title Diagnostic Pathology
Volume volume8
Publisher BioMed Central
Start Page 81
ISSN 1746-1596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 23675804
DOI 10.1186/1746-1596-8-81
Web of Science KeyUT 000319266300002
Related Url https://doi.org/10.1186/1746-1596-8-81 http://ousar.lib.okayama-u.ac.jp/54287
JaLCDOI 10.18926/ESR/55324
Title Alternative A case study on the cyclone activity around Europe from winter to spring of 2000
FullText URL esr_023_1_033_042.pdf
Author Kuwana, Yusuke| Kato, Kuranoshin| Takigawa, Yumi| Kojima, Yumi| Otani, Kazuo|
Abstract Although the extratropical cyclone is one of the basic systems that characterize the weather and climate in mid-latitude regions with the large meridional temperature gradient, its activity and characteristics would be greatly influenced by the seasonal transition and regional differences of the mean atmospheric fields such as between Europe and East Asia. Furthermore, detailed knowledge of the daily cyclone activity would help to understand deeply the differences of regional climatology including seasonal cycles among various areas. In such interest, the present study performed a case study on the cyclone activity around Europe from winter to spring of 2000. In winter, intraseasonal variation of the Icelandic Low was dominant. In the stage when such intraseasonal-scale Icelandic Low approached to the northwestern Europe, the several lows passed eastward with a few days interval around the intraseasonal-scale low pressure area or its southern edge where the baroclinicity was relatively strong. It is also noted that their center pressure was rather low (below 980hPa). After April, when the seasonal mean Icelandic low had disappeared, different types of the intra-seasonal-scale cyclones and anticyclones were dominantly observed. In the lower SLP stage of the intraseasonal variation in Europe, the low to the southwest of England in the middle of April was of the equivalent barotropic structure and persisted for about ten days. On the other hand, high pressure area extending from England to the northern coast of Germany also persisted for about half month. The southern half of that high area was also of equivalent barotropic structure with warmer air there.
Keywords cyclone activity around Europe comparative climatology between Europe and East Asia seasonal cycle dynamic climatology
Publication Title Okayama University Earth Science Report
Published Date 2016-12-27
Volume volume23
Issue issue1
Start Page 33
End Page 42
ISSN 1340-7414
language Japanese
Copyright Holders © 2016 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
File Version publisher
JaLCDOI 10.18926/ESR/55323
Title Alternative Synoptic climatological analyses on the rainfall features in southern Kyushu and the atmospheric fields around April
FullText URL esr_023_1_017_032.pdf
Author Kato, Kuranoshin| Morizuka, Nozomi| Matsumoto, (Kengo| Otani, Kazuo|
Abstract Around April, total precipitation in southern Kyushu already attains rather large value due to the increase in contribution of the “heavy rainfall days” (with daily precipitation more the 50 mm/day, referred to as HRD). The present study examined the rainfall features and atmospheric conditions on the HRDs at Kagoshima in southern Kyushu, based on the operational observation data from 1990 to 2009. The HRDs there in April appeared mainly associated with the extratropical cyclone passage, together with tentative appearance of the stationary front. The mean daily precipitation on the HRDs was 82 mm and contribution of the intense rainfall more than 10 mm/h attained up to 38 mm, which accounted for 46 % of the daily total precipitation. In April, the high specific humidity area in the time mean field was still located far to the south of the Japan Islands and the stratification around the Japan Islands was very stable for deep moist convection. However, the zone with rather strong seasonal mean baroclinicity extended to rather southern area near 20°N. This would provide a favorable condition for the long-distance moistur
Keywords heavy rainfall around April in southern Kyushu rainfall associated with extratropical cyclones around the Japan Islands seasonal cycle around Japan
Publication Title Okayama University Earth Science Report
Published Date 2016-12-27
Volume volume23
Issue issue1
Start Page 17
End Page 32
ISSN 1340-7414
language Japanese
Copyright Holders © 2016 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
File Version publisher
JaLCDOI 10.18926/ESR/55322
FullText URL esr_023_1_009_015.pdf
Author Takesue, Norito| Suzuki, Shigeyuki|
Abstract Analyzing of sedimentary facies and structure together with regional field mapping were studied in the mélange unit, upper Cretaceous Shimanto Belt, Wakayama Pref., SW Japan. The field survey was concentrated in the coast of Shiofuki-iwa, Miyama Complex, Hidakagawa Belt where soft deformations penetrate throughout the mélange unit. Brittle to ductile faults associated as later deformations are excluded. The mélange unit is subdivided into the Y-shear zone (YSZ) and P-foliation zone (PFZ). The YSZ is composed of thick lenticular sandstone (trends subparallel to the direction of the mélange), intense shear band (thin layer with concentrated prelithification shear deformation) and mudstone dominant mélange. The PFZ is composed of mudstone dominant mélange (associated with foliations which slightly oblique to the direction of the YSZ) and lenticular sandstone (slightly oblique to the direction of the YSZ). The intense shear band separates the YSZ and PFZ. Preserved radiolarian fossils free from deformation in the intense shear band is the evidence of the prelithification shear deformation in the mélange. A remarkable-fact is that the structures of mélange unit are formed under sinistral sense of shear. The mélange unit in the Shiofuki-iwa is ascribed to be formed by sinistral sense of shear during sediments were prelithified.
Keywords mélange Shimanto Belt Y-shear zone P-foliation zone intense shear band prelithification structures
Publication Title Okayama University Earth Science Report
Published Date 2016-12-27
Volume volume23
Issue issue1
Start Page 9
End Page 15
ISSN 1340-7414
language English
Copyright Holders © 2016 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
File Version publisher
FullText URL Vasc_Health_Risk_Manag_11_265.pdf
Author Saito, Yukihiro| Nakamura, Kazufumi| Akagi, Satoshi| Sarashina, Toshihiro| Ejiri, Kentaro| Miura, Aya| Ogawa, Aiko| Matsubara, Hiromi| Ito, Hiroshi|
Keywords apoptosis prostacyclin pulmonary arterial hypertension
Note 学位審査副論文|
Published Date 2015-05-14
Publication Title Vascular Health and Risk Management
Volume volume11
Publisher Dove Medical Press
Start Page 265
End Page 270
ISSN 1176-6344
NCID AA12158664
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 25999730
DOI 10.2147/VHRM.S50368
Web of Science KeyUT 000210424400027
Related Url https://doi.org/10.2147/VHRM.S50368 http://ousar.lib.okayama-u.ac.jp/55246
FullText URL K0005571_orher1.pdf K0005571_summary2.pdf
Author Iribe, Gentaro| Kaneko, Toshiyuki| Yamaguchi, Yohei| Naruse, Keiji|
Keywords Cell mechanics Mechano-electric coupling Modeling Shortening deactivation
Note 学位審査副論文|
Published Date 2014-08
Publication Title Progress in Biophysics and Molecular Biology
Volume volume115
Issue issue2-3
Publisher Pergamon Press
Start Page 103
End Page 114
ISSN 0079-6107
NCID AA00789136
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 24976617
DOI 10.1016/j.pbiomolbio.2014.06.005
Web of Science KeyUT 000344424700005
Related Url https://doi.org/10.1016/j.pbiomolbio.2014.06.005 http://ousar.lib.okayama-u.ac.jp/55243
FullText URL SciRep_7_1_7826.pdf
Author Takatani, Shogo| Ozawa, Shinichiro| Yagi, Noriyoshi| Hotta, Takashi| Hashimoto, Takashi| Takahashi, Yuichiro| Takahashi, Taku| Motose, Hiroyasu|
Keywords Cell growth Microtubules Plant cytoskeleton
Note Published in Scientific Reports. 7, 7826(2017)|
Published Date 2017-08-10
Publication Title Scientific Reports
Volume volume7
Publisher Nature Publishing Group
Start Page 7826
ISSN 20452322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 28798328
DOI 10.1038/s41598-017-08453-5
Web of Science KeyUT 000407400500058
Related Url isVersionOf https://doi.org/10.1038/s41598-017-08453-5
FullText URL BBRC_480_4_564.pdf BBRC_480_4_564_highlights.pdf BBRC_480_4_564_fig.pdf BBRC_480_4_564_suppl_fig.pdf
Author Ujihara, Yoshihiro| Mohria, Satoshi| Katanosaka, Yuki|
Keywords Heart failure Junctophilin-2 L-type Ca(2+) channel Na(+)/Ca(2+) exchanger 1 Pressure-overloading Transverse-tubule
Note 2017年11月公開予定|
Published Date 2016-11
Publication Title Biochemical and Biophysical Research Communications
Volume volume480
Issue issue4
Publisher Elsevier
Start Page 564
End Page 569
ISSN 0006-291X
NCID AA00564395
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 27789286
DOI 10.1016/j.bbrc.2016.10.090
Web of Science KeyUT 000389015400011
Related Url https://doi.org/10.1016/j.bbrc.2016.10.090
JaLCDOI 10.18926/AMO/55314
FullText URL 71_4_357.pdf
Author Tomoda, Takeshi| Kato, Hironari| Mizukawa, Sho| Muro, Shinichiro| Akimoto, Yutaka| Uchida, Daisuke| Matsumoto, Kazuyuki| Yamamoto, Naoki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki|
Abstract In the article by Tomoda T et al. entitled “A Multicenter, Prospective, Randomized Controlled Trial Evaluating the Efficacy of Rectal Diclofenac and Sublingual Nitroglycerin as a Combined Prophylactic Treatment for Post-ERCP Pancreatitis”, which appeared in the October 2016 issue, Vol. 70, No. 5, pp405-408, the word “nitroglycerin” should be corrected to “nitrate” throughout the manuscript.
Keywords post-ERCP pancreatitis NSAIDs nitrate
Amo Type Corrected and Republished Article
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 357
End Page 362
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824193
Related Url replaces http://doi.org/10.18926/AMO/54602
JaLCDOI 10.18926/AMO/55313
FullText URL 71_4_351.pdf
Author Araki, Motoo| Wada, Koichiro| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Yoshioka, Takashi| Ariyoshi, Yuichi| Fujio, Kei| Takamoto, Atsushi| Sugimoto, Morito| Sasaki, Katsumi| Kobayashi, Yasuyuki| Ebara, Shin| Taninishi, Hideki| Amano, Hiroyuki| Inui, Masashi| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo|
Abstract A 38-year-old woman with a 2.7-cm left ureteral stenosis requiring chronic ureteral stent exchange elected to undergo robotic renal autotransplantation. Left ureteropelvic junction obstruction (UPJO) was also suspected. Robotic donor nephrectomy contributed to the fine dissection for desmoplastic changes. The kidney was removed through a Gelport and examined on ice. UPJO was not seen. An end-to-side robotic anastomosis was created between the renal and external iliac vessels. The console time was 507 min, and the warm ischemia time was 4 min 5 sec. She became stent-free. Robotic renal autotransplantation is a new, minimally invasive approach to renal preservation.
Keywords robotic surgery renal autotransplantation ureteral stenosis laparoscopic surgery renal transplantation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 351
End Page 355
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824192
JaLCDOI 10.18926/AMO/55312
FullText URL 71_4_345.pdf
Author Tanaka, Masato| Sugimoto, Yoshihisa| Takigawa, Tomoyuki| Kimata, Yoshihiro| Ozaki, Toshifumi|
Abstract Osteoradionecrosis (ORN), a well-known complication of radiotherapy in the mandibular bone, is very rare in the cervical spine. The authors report the result of a 3-year follow-up of a 63-year-old female patient with ORN of the cervical spine. The patient had a history of laryngeal carcinoma and was treated with chemotherapy and radiation therapy with a total of 120 Gy. Eight years later, she developed acute, severe neck pain due to cervical spine necrosis. The authors performed vascularized fibular bone graft and posterior pedicle screw fixation to reconstruct her cervical spine. The patient was successfully treated with surgery, and cervical alignment was preserved. She had neither neurological deficits nor severe neck pain at her final follow-up 3 years later. Delaying treatment of ORN may be life threatening, so the early diagnosis of this condition is important for patients who receive radiotherapy. Otolaryngologists and spine surgeons should understand this potential complication to speed diagnosis and treatment as early as possible.
Keywords osteoradionecrosis laryngeal carcinoma cervical spine radiotherapy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 345
End Page 349
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824191
JaLCDOI 10.18926/AMO/55311
FullText URL 71_4_341.pdf
Author Yamazaki, Kenji| Wakabayashi, Hiroshi| Suganami, Yu| Sano, Shinichi| Wakunami, Yu| Katayama, Takashi| Deguchi, Kentaro| Nagotani, Shoko| Kishida, Masayuki|
Abstract We report a case of a woman with typical dermatomyositis (DM) with skin manifestations, severe myalgia and muscle weakness complicated by interstitial lung disease (ILD) and pneumomediastinum. Pneumomediastinum persisted despite treatment with immunosuppressive therapy (steroids and cyclosporine). After the test for anti-melanoma differentiation-associated gene 5 (MDA5) antibody came out positive, we doubled the cyclosporine dose and her condition improved. Despite typical clinical features of DM, in cases complicated by pneumomediastinum or steroid resistance, measurement of anti-MDA5 antibody may be useful for immunosuppressant dose titration.
Keywords dermatomyositis anti-melanoma differentiation-associated gene 5 antibody interstitial lung disease pneumomediastinum
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 341
End Page 344
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824190
JaLCDOI 10.18926/AMO/55310
FullText URL 71_4_333.pdf
Author Otani, Yusuke| Okabayashi, Takehiro| Shima, Yasuo| Shibuya, Yuichi| Ozaki, Kazuhide| Iwata, Jun| Morita, Sojiro| Iiyama, Tatsuo|
Abstract This retrospective study evaluated the short- and long-term outcomes after surgical management for gastric cancer in hemodialysis patients compared to non-dialysis patients. Twelve hemodialysis patients were compared with a propensity score-matched cohort of 39 gastric cancer patients who had not undergone hemodialysis. Short- and long-term outcomes along with scores estimating physiological ability and surgical stress were evaluated in both groups. The incidence of postoperative morbidity according to the Clavien-Dindo classification was higher in the hemodialysis gastric cancer group than in the non-dialysis gastric cancer group. The 5-year overall survival rate in the non-dialysis group was 69.2% after surgical resection for gastric cancer and 22.2% in the hemodialysis group. Patients with preoperative risk scores≥0.48 had significantly poorer survival outcomes compared to those with preoperative risk scores<0.48 (5-year survival rate, 83.3% vs. 39.4%, respectively). Our analyses suggest that hemodialysis patients undergoing surgery for gastric cancer have a significantly poorer postoperative prognosis and an elevated risk of postoperative complications.
Keywords gastric cancer surgery hemodialysis outcomes prognosis ESRD
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 333
End Page 339
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824189
JaLCDOI 10.18926/AMO/55309
FullText URL 71_4_325.pdf
Author Kawamoto, Fumihiko| Matsuoka, Hiroyuki| Phamd, Nghiem Minh| Hayashi, Taeko| Kasahara, Yuichi| Dung, Nguyen The| Kido, Yasutoshi| Kanbe, Toshio| Tantulara, Indah S.|
Abstract We conducted a survey of glucose-6-phosphate dehydrogenase (G6PD) deficiency among newborn babies at Tu Du Hospital, Ho Chi Minh, southern Vietnam. A total of 90 deficient babies were detected, including 85 in the Kinh ethnic group, 4 Chinese, and 1 in the K’Ho minority group. In the Kinh ethnic group, G6PD variants such as G6PD Viangchan (n=32), Kaiping (n=11), Canton (n=8), Chinese-5 (n=7), Union (n=5) and Quing Yuan (n=4) were detected. A variant with silent mutations at 1311 C>T and IVS11 nt 93 T>C was also detected in 17 cases. A novel mutation (173 A>G) in exon 4 with a predicted amino acid change of 58 Asp>Gly was also found in a Kinh newborn girl and her father, and it was designated as G6PD Ho Chi Minh. These findings demonstrated that the Kinh ethnic group in southern Vietnam has 8 different G6PD variants, indicating that the members of this group have many ancestors in terms of G6PD variants from Southeast Asia, China, and Oceania. We compared the frequency distribution of G6PD variants in the Kinh population with those of other Southeast Asian populations, and the Kinh population’s distribution was quite similar to that in the Thai population, but differed from it by the absence of G6PD Mahidol.
Keywords G6PD deficiency G6PD variant southern Vietnam Kinh population Southeast Asia
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 325
End Page 332
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824188
JaLCDOI 10.18926/AMO/55308
FullText URL 71_4_315.pdf
Author Fujii, Yosuke| Endo, Hirosuke| Mitani, Shigeru| Akazawa, Hirofumi| Tetsunaga, Tomonori| Miyake, Takamasa| Yamada, Kazuki| Aoki, Kiyoshi| Ozaki, Toshifumi|
Abstract We retrospectively reviewed 29 hips in which intertrochanteric osteotomies were performed for severe slipped capital femoral epiphyses. Mean age at surgery: 12.6 years. Mean follow-up period: 6 years. At the final follow-up evaluation, one patient had coxalgia, and six hips showed a limited range of motion. A pistol-grip deformity was observed in 13 hips, osteoarthritis in two hips, and a bump existed in 19 hips on the latest radiographs. Gradual remodeling of the bumps was observed post-operatively in 22 hips. The mean α and β angles and offset α and β improved over time. The remodeling proceeded rapidly for 1 year post-surgery. We compared hips classified as β angles of ≥ 63° to < 63° at the final follow-up evaluation, the mean β angle 1 year post-surgery, and the mean ratio of improvement of the β angle per year from 1 year post-surgery to the final follow up, which differed significantly. Nearly all of the patients who underwent intertrochanteric osteotomies had residual morphologic abnormalities, but few had clinical symptoms. The β angle 1 year post-surgery and the ratio of remodeling of the bump from 1 year post-surgery to the final follow-up can be regarded as a potential predictor of morphologic results after intertrochanteric osteotomy.
Keywords slipped capital femoral epiphyses intertrochanteric osteotomy residual femoral deformity femoroacetabular impingement bone remodeling
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 315
End Page 323
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824187
JaLCDOI 10.18926/AMO/55307
FullText URL 71_4_309.pdf
Author Asakura, Rie| Miyatake, Nobuyuki| Dokai Mochimasu, Kazumi| Kurato, Risa| Kuwana, Susumu|
Abstract We investigated the link between proteinuria and psychological distress among patients with type 2 diabetes mellitus (T2DM). A total of 130 patients with T2DM aged 69.1±10.3 years were enrolled in this cross-sectional study. Urine and blood parameters, age, height, body weight, and medications were analyzed, and each patient’s psychological distress was measured using the six-item Kessler Psychological Distress Scale (K6). We compared the K6 scores between the patients with and without proteinuria. Forty-two patients (32.3%) had proteinuria (≥±) and the level of HbA1c was 7.5±1.3%. The K6 scores of the patients with proteinuria were significantly higher than those of the patients without proteinuria even after adjusting for age and sex. The clinical impact of proteinuria rather than age, sex and HbA1c was demonstrated by a multiple regression analysis. Proteinuria was closely associated with higher psychological distress. Preventing and improving proteinuria may reduce psychological distress in patients with T2DM.
Keywords proteinuria psychological distress K6 type 2 diabetes mellitus
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 309
End Page 314
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824186
JaLCDOI 10.18926/AMO/55306
FullText URL 71_4_301.pdf
Author Taniguchi, Takaya| Taniguchi, Wataru| Miyamoto, Erabu| Miyazaki, Nobuyuki| Yoshida, Munehito|
Abstract Two-stage revision total hip arthroplasty (THA) is the most commonly used treatment approach for deep prosthetic infection. However, in this approach the interval between the first and second stage tends to be prolonged. We devised a strategic protocol for improving the infection eradication rate and shortening the interval between the stages in two-stage revision THA. This study analyzed a series of 14 patients (14 hips) from 2008 to 2012, who were treated using an antibiotic-loaded acrylic cement (ALAC) spacer at the first stage and re-implantation at the second stage. The ALAC included vancomycin and amikacin for most of the cases. Patients with MRSA infection were additionally administered intravenous vancomycin in combination with either oral rifampicin or trimethoprim-sulfamethoxazole. The average interval between the stages was 54.2 days overall, and 58.7 days for cases with MRSA infection. Our infection eradication rate was 100%, with no reported recurrence of infection. The presence of MRSA tended to be associated with a longer interval between the two stages. Our protocol for two-stage revision THA was associated with a high eradication rate of infection and a shortened interval between the stages.
Keywords two-stage revision infection total hip arthroplasty antibiotic-loaded acrylic cement, methicillinresistant Staphylococcus aureus (MRSA)
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 301
End Page 307
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824185
JaLCDOI 10.18926/AMO/55305
FullText URL 71_4_291.pdf
Author Naganuma, Atsushi| Hoshino, Takashi| Suzuki, Yuhei| Uehara, Daisuke| Kudo, Tomohiro| Ishihara, Hiroshi| Sato, Ken| Kakizaki, Satoru| Yamada, Masanobu| Takagi, Hitoshi|
Abstract The effect of skeletal muscle mass (SMM) on the outcomes of sorafenib treatment for hepatocellular carcinoma (HCC) has not been established. We measured the SMM in HCC patients treated with sorafenib, evaluated the patients’ survival, and evaluated the association between skeletal muscle depletion and sorafenib treatment. Of the 97 HCC patients treated with sorafenib at our institution in the period from July 2009 to February 2015, our study included 69 patients (51 males, 18 females) who had received sorafenib for ≥ 8 weeks and whose follow-up data were available. SMM was calculated from computed tomography images at the mid-L3 level (cm2) and normalized to height (m2) to yield the L3 skeletal muscle index (L3-SMI, cm2/m2). The median L3-SMI value was higher in the males (43 cm2/m2) compared to the females (36 cm2/m2). In the males only, the multivariate Cox regression identified an L3-SMI <43 cm2/m2 as independently associated with higher mortality compared to an L3-SMI ≥43 cm2/m2 (hazard ratio 2.315, 95% confidence interval: 1.125-4.765, p=0.023). Skeletal muscle depletion is a factor predicting poor prognosis for male patients with advanced HCC treated with sorafenib.
Keywords skeletal muscle depletion hepatocellular carcinoma sorafenib L3 skeletal muscle index prognostic factor
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-08
Volume volume71
Issue issue4
Publisher Okayama University Medical School
Start Page 291
End Page 299
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28824184