| ID | 31771 |
| JaLCDOI | |
| FullText URL | |
| Author |
Yamasato, Teruhiro
Takaki, Miyako
Nakayama, Sosogu
|
| Abstract | Trimebutine at low concentrations (6 X 10(-9)-1.4 X 10(-8) M) slightly enhanced the twitch response of isolated guinea pig ileum induced by transmural stimulation. At high concentrations (2 X 10(-8)-2 X 10(-7) M), however, it inhibited the twitch response in a dose dependent manner. This inhibitory effect of trimebutine was reversed by naloxone (8.1 X 10(-9) M). These results suggest that trimebutine has an opiate-like action on the myenteric plexus. |
| Keywords | naloxone
trimebutine
twitch respose
|
| Amo Type | Article
|
| Publication Title |
Acta Medica Okayama
|
| Published Date | 1987-02
|
| Volume | volume41
|
| Issue | issue1
|
| Publisher | Okayama University Medical School
|
| Start Page | 33
|
| End Page | 35
|
| ISSN | 0386-300X
|
| NCID | AA00508441
|
| Content Type |
Journal Article
|
| language |
English
|
| File Version | publisher
|
| Refereed |
True
|
| PubMed ID | |
| Web of Science KeyUT |
