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Berberine improved experimental chronic colitis by regulating interferon-gamma- and IL-17A-producing lamina propria CD4(+) T cells through AMPK activation
FullText URL SR9_1_11934.pdf
Author Takahara, Masahiro| Takaki, Akinobu| Hiraoka, Sakiko| Adach, Takuya| Shimomura, Yasuyuki| Matsushita, Hiroshi| Nguyen Tien Thi Thuy| Koike, Kazuko| Ikeda, Airi| Takashima, Shiho| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Sugihara, Yusaku| Harada, Keita| Eikawa, Shingo| Morita, Hidetoshi| Udono, Heiichiro| Okada, Hiroyuki|
Published Date 2019-8-15
Publication Title Scientific Reports
Volume volume9
Publisher Nature Publishing Group
Start Page 11934
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2019
File Version publisher
PubMed ID 31417110
DOI 10.1038/s41598-019-48331-w
Web of Science KeyUT 000480680800048
Related Url isVersionOf https://doi.org/10.1038/s41598-019-48331-w
Attenuation of CD4+ CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug
FullText URL EBioMedicine_2017_154.pdf
Author Kunisada, Yuki| Eikawa, Shingo| Tomonobu, Nahoko| Domae, Shohei| Uehara, Takenori| Hori, Shohei| Furusawa, Yukihiro| Hase, Koji| Sasaki, Akira| Udono, Heiichiro|
Keywords Glycolysis Regulatory T cell (Treg) Tumor immunity Tumor microenvironment mTOR
Published Date 2017-10-16
Publication Title EBioMedicine
Volume volume25
Publisher Elsevier Science
Start Page 154
End Page 164
ISSN 23523964
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2017 The Authors.
File Version publisher
PubMed ID 29066174
DOI 10.1016/j.ebiom.2017.10.009
Web of Science KeyUT 000417440500026
Related Url isVersionOf https://doi.org/10.1016/j.ebiom.2017.10.009
アルツハイマー型認知症患者の腸内細菌叢によるヒト型モデルマウスの構築とこの構築マウスの認知行動に腸内環境が及ぼす影響
FullText URL K0006073_abstract_review.pdf K0006073_summary.pdf
Author Fujii, Yusuke|
Published Date 2019-09-25
Content Type Thesis or Dissertation
Grant Number 甲第6073号
Granted Date 2019-09-25
Thesis Type Doctor of Philosophy in Agriculture
Grantor 岡山大学
language Japanese
ラットを用いた化学物質曝露による生体内ホルモンレベルの変動要因解析
FullText URL K0006071_abstract_review.pdf K0006071_fulltext.pdf
Author Yamaguchi, Takafumi|
Published Date 2019-09-25
Content Type Thesis or Dissertation
Grant Number 甲第6071号
Granted Date 2019-09-25
Thesis Type Doctor of Philosophy
Grantor 岡山大学
language Japanese
Acidic Pre-Conditioning Enhances the Stem Cell Phenotype of Human Bone Marrow Stem/Progenitor Cells
FullText URL K0006044_abstract_review.pdf.pdf summary.pdf.pdf fulltext.pdf.pdf
Author Kunitomo, Yuri|
Published Date 2019-09-25
Content Type Thesis or Dissertation
Grant Number 甲第6044号
Granted Date 2019-09-25
Thesis Type Doctor of Philosophy in Dental Science
Grantor 岡山大学
language English
The Novel Combination of Nitroxoline and PD-1 Blockade, Exerts a Potent Antitumor Effect in a Mouse Model of Prostate Cancer
FullText URL K0006039_abstract_review.pdf K0006039_fulltext.pdf
Author Xu, Naijin|
Published Date 2019-09-25
Content Type Thesis or Dissertation
Grant Number 甲第6039号
Granted Date 2019-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma
FullText URL K0006024_abstract_review.pdf K0006024_fulltext.pdf K0006024_other_1 figure.pdf K0006024_other_2 Supplementary figures and legends.pdf
Author Watanabe, Shin-ichiro|
Published Date 2019-09-25
Content Type Thesis or Dissertation
Grant Number 甲第6024号
Granted Date 2019-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Sequence and phylogenetic analyses of novel totivirus-like double-stranded RNAs from field-collected powdery mildew fungi
FullText URL VirusRes_213_353.pdf tables_revised.pdf Fig S.pdf Supplementary_tables_revised.pdf
Author Kondo, Hideki| Hisano, Sakae| Chiba, Sotaro| Maruyama, Kazuyuki| Andika, Ida Bagus| Toyoda, Kazuhiro| Fujimori, Fumihiro| Suzuki, Nobuhiro|
Keywords Deep sequencing Double stranded RNA virus Powdery mildew Saccharomyces cerevisiae virus L-A Totivirus Ustilago maydis virus H1
Published Date 2016-02
Publication Title Virus Research
Volume volume213
Publisher Elsevier Science
Start Page 353
End Page 364
ISSN 01681702
NCID AA10642076
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 26592174
DOI 10.1016/j.virusres.2015.11.015
Web of Science KeyUT 000371840600042
Related Url isVersionOf https://doi.org/10.1016/j.virusres.2015.11.015
第118回　岡山医学会総会
Title Alternative The 118th General Assembly of the Okayama Medical Association
FullText URL 131_115.pdf
Publication Title Journal of Okayama Medical Association
Published Date 2019-08-01
Volume volume131
Issue issue2
Start Page 115
End Page 121
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.115
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.115
NAID 130007700791
第93回　岡山胸部疾患懇話会
Title Alternative The 93rd Okayama Chest Disease Conference
FullText URL 131_113.pdf
Publication Title Journal of Okayama Medical Association
Published Date 2019-08-01
Volume volume131
Issue issue2
Start Page 113
End Page 114
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.113
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.113
NAID 130007700790
平成30年度岡山医学会賞が決まる
FullText URL 131_65.pdf
Publication Title Journal of Okayama Medical Association
Published Date 2019-04-01
Volume volume131
Issue issue1
Start Page 65
End Page 66
ISSN 0030-1558
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
遺伝性腫瘍とがん予防
Title Alternative Hereditary tumors and cancer prevention
FullText URL 131_83.pdf
Author Hirasawa, Akira|
Keywords 遺伝性腫瘍 がん予防 ゲノム医療 リスク低減手術 遺伝性乳癌卵巣癌
Publication Title Journal of Okayama Medical Association
Published Date 2019-08-01
Volume volume131
Issue issue2
Start Page 83
End Page 87
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.83
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.83
NAID 40021986719
平成30年度岡山医学会賞 がん研究奨励賞（林原賞・山田賞）
Title Alternative The 2018 Incentive Award of the Okayama Medical Association in Cancer Research (2018 Hayashibara Prize and Yamada Prize)
FullText URL 131_75.pdf
Author Kinoshita, Rie|
Publication Title Journal of Okayama Medical Association
Published Date 2019-08-01
Volume volume131
Issue issue2
Start Page 75
End Page 77
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.75
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.75
NAID 130007700793
平成30年度岡山医学会賞 脳神経研究奨励賞（新見賞）
Title Alternative The 2018 Incentive Award of the Okayama Medical Association in Neuroscience (2018 Niimi Prize)
FullText URL 131_71.pdf
Author Kin , Kyohei |
Publication Title Journal of Okayama Medical Association
Published Date 2019-08-01
Volume volume131
Issue issue2
Start Page 71
End Page 73
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.71
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.71
NAID 40021986706
平成30年度岡山医学会賞 総合研究奨励賞（結城賞）
Title Alternative The 2018 Incentive Award of the Okayama Medical Association in General Medical Science (2018 Yuuki Prize)
FullText URL 131_67.pdf
Author Mise, Koki |
Publication Title Journal of Okayama Medical Association
Published Date 2019-08-01
Volume volume131
Issue issue2
Start Page 67
End Page 69
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.67
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.67
NAID 40021986701
第49回　岡山リウマチ研究会
Title Alternative The 49th Okayama Rheumatology Conference
FullText URL 131_61.pdf
Publication Title Journal of Okayama Medical Association
Published Date 2019-04-01
Volume volume131
Issue issue1
Start Page 61
End Page 64
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.61
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.61
NAID 130007642645
免疫チェックポイント阻害薬の効果を左右する腫瘍微小環境
Title Alternative Tumor microenvironment affecting the effect of immuno-checkpoint inhibitors
FullText URL 131_51.pdf
Author Nishii, Kazuya | Ohashi , Kadoaki | Kiura, Katsuyuki |
Publication Title Journal of Okayama Medical Association
Published Date 2019-04-01
Volume volume131
Issue issue1
Start Page 51
End Page 53
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.51
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.51
NAID 130007642652
薬物相互作用（44―関節リウマチの分子標的治療薬）
Title Alternative Drug interaction（44. Combination with molecular target drugs in rheumatoid arthritis）
FullText URL 131_47.pdf
Author Maruo, Akinori| Esumi, Satoru | Kitamura, Yoshihisa| Sendo, Toshiaki|
Publication Title Journal of Okayama Medical Association
Published Date 2019-04-01
Volume volume131
Issue issue1
Start Page 47
End Page 50
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.47
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.47
NAID 130007642644
内科におけるコンピュータ利用診断支援システムによる診断改善
Title Alternative Better diagnostic performance using computer-assisted diagnostic support systems in internal medicine
FullText URL 131_29.pdf
Author Kuriyama, Yutaka| Sota , Yumi| Yano, Aika| Yasuda, Hideki| Ishii, Osamu| Saio , Takeo| Torigoe, Keijiro| Ueda, Takeshi | Shimizu , Tarou | Tokuda, Yasuharu|
Abstract The recent application of artificial intelligence（AI）to clinical medicine has confirmed the usefulness of AI for diagnostic imaging, histopathological examinations, and dermatologic screening. Clinical decision support systems are another promising area to which AI could contribute toward better clinical decisions. We have developed computer-assisted diagnostic support systems to reduce human diagnostic errors such as delayed diagnoses, misdiagnoses, and overdiagnoses. Our three Diagnosis Reminder（DR）systems include two AI systems that use machine learning in their diagnosis algorithms. Here, we compared the diagnostic accuracy of a DR-supported group with that of an unassisted physicians group, using three difficult patient cases provided by experts in general medicine. 　Our analyses revealed that the three AI diagnostic systems could not provide accurate differential diagnoses up to top 10 in all three patient cases because of incomplete data inputs for machine learning. However, the first DR system, which was developed by an experienced diagnostician over the last 35 years, showed very useful performance in reducing human diagnostic errors when it was used by an expert physician. The use of AI diagnostic systems by knowledgeable physicians will lead to better diagnostic performance. We also discuss the current scenario, future challenges, and prospects for AI diagnostic systems herein.
Keywords AI 診断システム (AI diagnostic systems) 診断思い出し (diagnosis reminder) 機械学習 (machine learning) 診断エラー (human diagnostic errors)
Publication Title Journal of Okayama Medical Association
Published Date 2019-04-01
Volume volume131
Issue issue1
Start Page 29
End Page 34
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.29
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.29
NAID 130007642655
平成29年度岡山医学会賞 総合研究奨励賞（結城賞）
Title Alternative The 2017 Incentive Award of the Okayama Medical Association in General Medical Science (2017 Yuuki Prize)
FullText URL 131_9.pdf
Author Katsuyama, Eri|
Publication Title Journal of Okayama Medical Association
Published Date 2019-04-01
Volume volume131
Issue issue1
Start Page 9
End Page 11
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.131.9
language Japanese
Copyright Holders Copyright (c) 2019 岡山医学会
File Version publisher
DOI 10.4044/joma.131.9
NAID 130007642647
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