| ID | 17671 |
| Eprint ID | 17671
|
| FullText URL | |
| Title Alternative | In vitro transformation of mouse embryo cells by SV 40 DNA
|
| Author |
Yamamoto, Shinichiro
Egusa, Kuniyuki
Oda, Takuzo
|
| Abstract | The oncogenicity of SV 40 DNA was examined in mouse embryo cell cultures in vitro. T antigen induction in mouse embryo cells by SV 40 DNA was predominant at 5 days after infection and T antigen positive cells were observed by more than 10% at this stage. They decreased with increasing time until about 30 to 50 days of culture, after which numbers of cells with positive T antigen increased again to 36 to 38% with morphological changes accompanied. Morphological alterations seen at about 100 days after infection were characteristic of SV 40 transformed cells, e.g., criss-cross appearance, giant cell formation and irregurality of cell arrangements.
|
| Published Date | 1971-08-30
|
| Publication Title |
岡山医学会雑誌
|
| Publication Title Alternative | Journal of Okayama Medical Association
|
| Volume | volume83
|
| Issue | issue7-8
|
| Publisher | 岡山医学会
|
| Publisher Alternative | Okayama Medical Association
|
| Start Page | 267
|
| End Page | 271
|
| ISSN | 0030-1558
|
| NCID | AN00032489
|
| Content Type |
Journal Article
|
| Official Url | https://www.jstage.jst.go.jp/article/joma1947/83/7-8/83_7-8_267/_article/-char/ja/
|
| Related Url | http://www.okayama-u.ac.jp/user/oma/
|
| language |
Japanese
|
| Copyright Holders | 岡山医学会
|
| File Version | publisher
|
| Refereed |
True
|
| Eprints Journal Name | joma
|
