| ID | 65774 |
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| Author |
Ono, Ryota
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Saeki, Nozomu
Research Core for Interdisciplinary Sciences, Okayama University
Kojima, Keiichi
Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Moriya, Hisao
Research Core for Interdisciplinary Sciences, Okayama University
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Sudo, Yuki
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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| Abstract | Upon white light illumination, the growth of the budding yeast Saccharomyces cerevisiae was extremely impaired only in the presence of iodide ions, but not fluoride, chloride and bromide ions. Action spectroscopy revealed that the maximum wavelength of the light is around at 373 nm, corresponding to the UVA region. Using a genetic approach, several genes, including OPY1, HEM1, and PAU11, were identified as suppressors of this growth inhibition. This iodide-dependent UVA-triggered growth inhibition method, along with its suppressive molecules, would be beneficial for understanding cell growth processes in eukaryotes and can be utilized for medium sterilization using UVA light.
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| Keywords | UVA
Saccharomyces cerevisiae
Iodide
Growth inhibition
Suppressive molecule
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| Note | © 2023 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
This fulltext file will be available in Oct. 2024.
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| Published Date | 2023-10-15
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| Publication Title |
Biochemical and Biophysical Research Communications
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| Volume | volume677
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| Publisher | Elsevier BV
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| Start Page | 1
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| End Page | 5
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| ISSN | 0006-291X
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| NCID | AA00564395
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| Content Type |
Journal Article
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| language |
English
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| OAI-PMH Set |
岡山大学
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| Copyright Holders | © 2023 Elsevier Inc.
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| File Version | author
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| PubMed ID | |
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| Related Url | isVersionOf https://doi.org/10.1016/j.bbrc.2023.07.048
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| License | https://creativecommons.org/licenses/by-nc-nd/4.0
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| Funder Name |
Japan Society for the Promotion of Science
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| 助成番号 | JP23H02449
JP18H02411
JP21H02446
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