result 15324 件
Title Alternative | Sjögren's syndrome |
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Author | Matsumoto, Yoshinori| |
Keywords | シェーグレン症候群 疫学 治療 特定疾患 |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 77 |
End Page | 79 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.77 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.77 |
Title Alternative | Acquired idiopathic generalized anhidrosis (AIGA) |
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Author | Kawakami, Yoshio| |
Keywords | コリン性蕁麻疹 ステロイドパルス 機能性高体温症 |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 74 |
End Page | 76 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.74 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.74 |
Title Alternative | A case of immune checkpoint inhibitor-associated colitis treated with infliximab |
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Author | Iwamuro, Masaya| Hiraoka, Sakiko| Otsuka, Motoyuki| |
Abstract | A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary. |
Keywords | インフリキシマブ(infliximab) 免疫関連有害事象(immune-related adverse events) 大腸炎(colitis) |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 69 |
End Page | 73 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.69 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.69 |
Title Alternative | Metformin-induced mitochondrial reactive oxygen species and host defense mechanisms |
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Author | Udono, Heiichiro| |
Keywords | CD8T 細胞 活性酸素 Nrf2 解糖系 ミトコンドリア |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 63 |
End Page | 68 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.63 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.63 |
Title Alternative | Five-year findings from the home blood pressure management study using IoT technology and future perspectives based on a time-series big data and AI analysis : the Masuda Study |
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Author | Hisamatsu, Takashi| Kinuta, Minako| Fukuda, Mari| Taniguchi, Kaori| Nakahata, Noriko| Kanda, Hideyuki| |
Keywords | 家庭血圧(home blood pressure) IoT AI ビックデータ(big data) |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 57 |
End Page | 62 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.57 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.57 |
Title Alternative | The 2023 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2023 Sunada Prize) |
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Author | Matsubara, Kei| |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 54 |
End Page | 56 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.54 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.54 |
Title Alternative | The 2023 Incentive Award of the Okayama Medical Association in Neuroscience (2023 Niimi Prize) |
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Author | Yabuno, Satoru| |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 51 |
End Page | 53 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.51 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.51 |
Title Alternative | The 2023 Incentive Award of the Okayama Medical Association in General Medical Science (2023 Yuuki Prize) |
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Author | Naito, Hiromichi| |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 48 |
End Page | 50 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.48 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.48 |
Title Alternative | The 2023 Incentive Award of the Okayama Medical Association in Cancer Research (2023 Hayashibara Prize and Yamada Prize) |
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Author | Ishino, Takamasa| |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 45 |
End Page | 47 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.45 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.45 |
FullText URL | fulltext20240822-01.pdf |
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Author | Kawase, Tomoka| Miura, Fumi| Debnath, Anusuya| Imakura, Kinuyo| Miyoshi, Shin-ichi| |
Keywords | Vibrio vulnificus Protease Propeptide Domain Cell-free translational system |
Note | © 2018 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| |
Published Date | 2018-09 |
Publication Title | Protein Expression and Purification |
Volume | volume149 |
Publisher | Elsevier BV |
Start Page | 13 |
End Page | 16 |
ISSN | 1046-5928 |
NCID | AA10814149 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2018 Elsevier Inc. |
File Version | author |
PubMed ID | 29635038 |
DOI | 10.1016/j.pep.2018.04.004 |
Web of Science KeyUT | 000434003700003 |
Related Url | isVersionOf https://doi.org/10.1016/j.pep.2018.04.004 |
FullText URL | fulltext.pdf |
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Author | Sumi, Tomonari| Harada, Kouji| |
Keywords | post-acute sequelae of SARS-CoV-2 infection PASC long Covid persistent viruses vaccine antiviral drug mathematical model immune response |
Published Date | 2024-08-09 |
Publication Title | Frontiers in Immunology |
Volume | volume15 |
Publisher | Frontiers Media |
Start Page | 1329162 |
ISSN | 1664-3224 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 Sumi and Harada. |
File Version | publisher |
PubMed ID | 39185419 |
DOI | 10.3389/fimmu.2024.1329162 |
Web of Science KeyUT | 001295899400001 |
Related Url | isVersionOf https://doi.org/10.3389/fimmu.2024.1329162 |
FullText URL | fulltext.pdf |
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Author | Fukao, Takashi| Fujiwara, Masaki| Yamada, Yuto| Sakamoto, Shinji| Matsumoto, Yosuke| Takaki, Manabu| |
Keywords | anti-seizure medications attention-deficit/hyperactivity disorder electroencephalography transient epileptic amnesia |
Published Date | 2024-08-22 |
Publication Title | Psychiatry and Clinical Neurosciences Reports |
Volume | volume3 |
Issue | issue3 |
Publisher | Wiley |
Start Page | e70003 |
ISSN | 2769-2558 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 The authors. |
File Version | publisher |
PubMed ID | 39184058 |
DOI | 10.1002/pcn5.70003 |
Web of Science KeyUT | 001295703300001 |
Related Url | isVersionOf https://doi.org/10.1002/pcn5.70003 |
FullText URL | fulltext.pdf |
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Author | Ueda, Masataka| Tetsunaga, Tomoko| Tetsunaga, Tomonori| Nishida, Keiichiro| Takatori, Ryo| Shitozawa, Hisakazu| Uotani, Koji| Shinohara, Kennsuke| Oda, Yoshiaki| Ozaki, Toshifumi| |
Keywords | AIS cognitive-behavioral therapy EQ5D HADS insomnia pain-liaison outpatient clinic sleep disorders |
Published Date | 2024-08-09 |
Publication Title | Medicine |
Volume | volume103 |
Issue | issue32 |
Publisher | Lippincott, Williams & Wilkins |
Start Page | e39113 |
ISSN | 0025-7974 |
NCID | AA00728867 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 the Author(s). |
File Version | publisher |
PubMed ID | 39121265 |
DOI | 10.1097/MD.0000000000039113 |
Web of Science KeyUT | 001287977800045 |
Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000039113 |
JaLCDOI | 10.18926/AMO/67554 |
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FullText URL | 78_4_349.pdf |
Author | Tominaga, Yuichiro| Sugaya, Akiko| Kariya, Shin| Shimizu, Aiko| Kataoka, Yuko| Ando, Mizuo| |
Abstract | Middle-ear salivary gland choristoma (SGCh) is a rare, benign tumor that causes conductive hearing loss owing to middle-ear morphological abnormalities. Early diagnosis is challenging, and surgical resection is indispensable for a definitive diagnosis. We report the case of a 3-year-old boy diagnosed with middle-ear SGCh during the follow-up period for left-sided hearing loss discovered at newborn hearing screening (NHS). Long-term follow-up after the NHS result, subsequent computed tomography/magnetic resonance imaging, and surgical resection led to its relatively early diagnosis and treatment. |
Keywords | middle-ear salivary gland choristoma middle-ear morphological abnormalities newborn hearing screening unilateral hearing loss surgical resection |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2024-08 |
Volume | volume78 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 349 |
End Page | 355 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39198990 |
Web of Science KeyUT | 001310557400004 |
JaLCDOI | 10.18926/AMO/67553 |
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FullText URL | 78_4_345.pdf |
Author | Kato, Gentaro| Narumiya, Yuto| Okuyama, Michihiro| Shimizu, Shuji| Sangawa, Kenji| Yamamoto, Shu| |
Abstract | The presence of an intraperitoneal source of infection, e.g., a liver abscess, can be an obstacle to performing an abdominal aortic surgery with a midline laparotomy because graft infection is one of the most critical complications of aortic surgery. We report the successful Y-grafting of a pararenal abdominal aortic aneurysm through a retroperitoneal approach in a 67-year-old male undergoing liver abscess drainage. The retroperitoneal approach to the abdominal aorta may be useful for abdominal aortic surgery in patients with a localized intraperitoneal infection. |
Keywords | blunt liver trauma liver abscess abdominal aortic aneurysm Y-grafting retroperitoneal approach |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2024-08 |
Volume | volume78 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 345 |
End Page | 347 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39198989 |
Web of Science KeyUT | 001310557400003 |
JaLCDOI | 10.18926/AMO/67550 |
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FullText URL | 78_4_337.pdf |
Author | Makihara, Seiichiro| Otani, Yoshihiro| Uraguchi, Kensuke| Ono, Sawako| Shimizu, Aiko| Ikemachi, Ryosuke| Okazaki, Yosuke| Ota, Tomoyuki| Matsumoto, Hiroshi| Miyamoto, Shotaro| Tsumura, Munechika| Hayashi, Seiya| Umakoshi, Michiari| Hirashita, Koji| Ando, Mizuo| |
Abstract | Here, we describe the unique case of a pneumocephalus originating from an inverted papilloma (IP) in the frontoethmoidal sinus. A 71-year-old man with diabetes presented with headaches and altered consciousness. Imaging revealed the pneumocephalus together with bone destruction in the left frontal sinus. He underwent simultaneous endoscopic endonasal and transcranial surgery using an ORBEYE exoscope. Pathological diagnosis of the tumor confirmed IP. Post-surgery, the pneumocephalus was significantly resolved and the squamous cell carcinoma antigen level, which had been elevated, decreased. This case underscores the importance of a multidisciplinary approach and innovative surgical methods in treating complex sinonasal pathologies. |
Keywords | pneumocephalus inverted papilloma frontoethmoidal sinus endoscopic endonasal and transcranial surgery |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2024-08 |
Volume | volume78 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 337 |
End Page | 343 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39198988 |
Web of Science KeyUT | 001310557400002 |
JaLCDOI | 10.18926/AMO/67549 |
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FullText URL | 78_4_331.pdf |
Author | Furukawa, Chieko| Tachibana, Tomoyasu| Nobuhisa, Tetsuji| Kanie, Yuichiro| Wani, Yoji| Matsumoto, Jun-Ya| Kariya, Akifumi| Sato, Asuka| Ishikawa, Iichiro| Naoi, Yuto| Ando, Mizuo| |
Abstract | No previous study has published magnetic resonance imaging (MRI) findings for a subglottic pleomorphic adenoma. Here, we describe the case of a 62-year-old man with a subglottic pleomorphic adenoma. Endoscopic findings revealed a smooth-surfaced tumor arising from the subglottic posterior wall. MRI revealed the lesion as an isointense region on T1-weighted images, which was homogeneously enhanced. This lesion showed a heterogeneously hyperintense region on T2-weighted images. Diffusion-weighted imaging (DWI) showed slightly high intensity in the same area, with a normal or only slightly high apparent diffusion coefficient (ADC). Laryngomicrosurgery was performed for transoral excision of the subglottic tumor, resulting in a postsurgical diagnosis of pleomorphic adenoma. |
Keywords | subglottis pleomorphic adenoma MRI transoral surgery |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2024-08 |
Volume | volume78 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 331 |
End Page | 335 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39198987 |
Web of Science KeyUT | 001310557400001 |
JaLCDOI | 10.18926/AMO/67548 |
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FullText URL | 78_4_323.pdf |
Author | Katayama, Akira| Kimura, Satoshi| Matsusaki, Takashi| Morimatsu, Hiroshi| |
Abstract | It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications. |
Keywords | pediatric liver transplantation postoperative severe complications Graft-to-Recipient Weight Ratio |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-08 |
Volume | volume78 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 323 |
End Page | 330 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39198986 |
Web of Science KeyUT | 001310576400003 |
JaLCDOI | 10.18926/AMO/67547 |
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FullText URL | 78_4_313.pdf |
Author | Eto, Eriko| Maki, Jota| Yamashita, Noriyuki| Hasegawa, Toru| Suemori, Ayano| Nakato, Hikari| Oba, Hikaru| Mitoma, Tomohiro| Mishima, Sakurako| Kirino, Satoe| Ohira, Akiko| Masuyama, Hisashi| |
Abstract | During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku–Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered “satisfied” or “very satisfied” with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable. |
Keywords | remote simulator education perinatal simulator information and communication technology high-flexibility education |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-08 |
Volume | volume78 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 313 |
End Page | 322 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39198985 |
Web of Science KeyUT | 001310576400002 |
JaLCDOI | 10.18926/AMO/67546 |
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FullText URL | 78_4_307.pdf |
Author | Sugihara, Naoya| Hashine, Katsuyoshi| Yamashita, Natsumi| Sakamoto, Miki| Terashita, Masato| Funaki, Keisuke| Saiki, Kaori| Sawada, Takatora| Kakuda, Toshio| Nishimura, Kenichi| Fukumoto, Tetsuya| Miura, Noriyosi| Miyauchi, Yuki| Kikugawa, Tadahiko| Saika, Takashi| |
Abstract | The Briganti nomogram (cut-off value 5%) is commonly used to determine the indications for pelvic lymph node dissection (PLND) in patients with prostate cancer. We retrospectively analyzed the potential oncological benefit of PLND based on the 5% cut-off value on the Briganti nomogram. We obtained the data from the Medical Investigation Cancer Network (MICAN) Study, which included 3,463 patients who underwent a radical prostatectomy (RP) at nine institutions in Japan between 2010 and 2020. We included patients with Briganti scores ≥ 5% and a follow-up period ≥6 months and excluded patients categorized in the very high-risk group (based on NCCN categories); a final total of the cases of 1,068 patients were analyzed. The biochemical recurrence (BCR)-free survival was significantly worse in the patients who underwent PLND compared to those who did not (p=0.019). A multivariate analysis showed that high prostate-specific antigen (PSA) levels (p<0.001) and an advanced T-stage (p=0.018) were significant prognostic factors for BCR, whereas PLND had no effect on BCR (p=0.059). Thus, PLND in patients with prostate cancer whose Briganti score was 5% did not provide any oncological benefit. Further research is necessary to determine the indication criteria for conducting PLND. |
Keywords | Briganti nomogram pelvic lymph node dissection prostate cancer radical prostatectomy |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-08 |
Volume | volume78 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 307 |
End Page | 312 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39198984 |
Web of Science KeyUT | 001310576400001 |