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Title Alternative Sjögren's syndrome
Author Matsumoto, Yoshinori|
Keywords シェーグレン症候群 疫学 治療 特定疾患
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 77
End Page 79
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.77
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.77
Title Alternative Acquired idiopathic generalized anhidrosis (AIGA)
Author Kawakami, Yoshio|
Keywords コリン性蕁麻疹 ステロイドパルス 機能性高体温症
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 74
End Page 76
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.74
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.74
Title Alternative A case of immune checkpoint inhibitor-associated colitis treated with infliximab
Author Iwamuro, Masaya| Hiraoka, Sakiko| Otsuka, Motoyuki|
Abstract  A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary.
Keywords インフリキシマブ(infliximab) 免疫関連有害事象(immune-related adverse events) 大腸炎(colitis)
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 69
End Page 73
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.69
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.69
Title Alternative Metformin-induced mitochondrial reactive oxygen species and host defense mechanisms
Author Udono, Heiichiro|
Keywords CD8T 細胞 活性酸素 Nrf2 解糖系 ミトコンドリア
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 63
End Page 68
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.63
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.63
Title Alternative Five-year findings from the home blood pressure management study using IoT technology and future perspectives based on a time-series big data and AI analysis : the Masuda Study
Author Hisamatsu, Takashi| Kinuta, Minako| Fukuda, Mari| Taniguchi, Kaori| Nakahata, Noriko| Kanda, Hideyuki|
Keywords 家庭血圧(home blood pressure) IoT AI ビックデータ(big data)
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 57
End Page 62
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.57
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.57
Title Alternative The 2023 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2023 Sunada Prize)
Author Matsubara, Kei|
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 54
End Page 56
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.54
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.54
Title Alternative The 2023 Incentive Award of the Okayama Medical Association in Neuroscience (2023 Niimi Prize)
Author Yabuno, Satoru|
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 51
End Page 53
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.51
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.51
Title Alternative The 2023 Incentive Award of the Okayama Medical Association in General Medical Science (2023 Yuuki Prize)
Author Naito, Hiromichi|
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 48
End Page 50
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.48
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.48
Title Alternative The 2023 Incentive Award of the Okayama Medical Association in Cancer Research (2023 Hayashibara Prize and Yamada Prize)
Author Ishino, Takamasa|
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 45
End Page 47
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.45
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.45
FullText URL fulltext20240822-01.pdf
Author Kawase, Tomoka| Miura, Fumi| Debnath, Anusuya| Imakura, Kinuyo| Miyoshi, Shin-ichi|
Keywords Vibrio vulnificus Protease Propeptide Domain Cell-free translational system
Note © 2018 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/|
Published Date 2018-09
Publication Title Protein Expression and Purification
Volume volume149
Publisher Elsevier BV
Start Page 13
End Page 16
ISSN 1046-5928
NCID AA10814149
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2018 Elsevier Inc.
File Version author
PubMed ID 29635038
DOI 10.1016/j.pep.2018.04.004
Web of Science KeyUT 000434003700003
Related Url isVersionOf https://doi.org/10.1016/j.pep.2018.04.004
FullText URL fulltext.pdf
Author Sumi, Tomonari| Harada, Kouji|
Keywords post-acute sequelae of SARS-CoV-2 infection PASC long Covid persistent viruses vaccine antiviral drug mathematical model immune response
Published Date 2024-08-09
Publication Title Frontiers in Immunology
Volume volume15
Publisher Frontiers Media
Start Page 1329162
ISSN 1664-3224
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Sumi and Harada.
File Version publisher
PubMed ID 39185419
DOI 10.3389/fimmu.2024.1329162
Web of Science KeyUT 001295899400001
Related Url isVersionOf https://doi.org/10.3389/fimmu.2024.1329162
FullText URL fulltext.pdf
Author Fukao, Takashi| Fujiwara, Masaki| Yamada, Yuto| Sakamoto, Shinji| Matsumoto, Yosuke| Takaki, Manabu|
Keywords anti-seizure medications attention-deficit/hyperactivity disorder electroencephalography transient epileptic amnesia
Published Date 2024-08-22
Publication Title Psychiatry and Clinical Neurosciences Reports
Volume volume3
Issue issue3
Publisher Wiley
Start Page e70003
ISSN 2769-2558
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The authors.
File Version publisher
PubMed ID 39184058
DOI 10.1002/pcn5.70003
Web of Science KeyUT 001295703300001
Related Url isVersionOf https://doi.org/10.1002/pcn5.70003
FullText URL fulltext.pdf
Author Ueda, Masataka| Tetsunaga, Tomoko| Tetsunaga, Tomonori| Nishida, Keiichiro| Takatori, Ryo| Shitozawa, Hisakazu| Uotani, Koji| Shinohara, Kennsuke| Oda, Yoshiaki| Ozaki, Toshifumi|
Keywords AIS cognitive-behavioral therapy EQ5D HADS insomnia pain-liaison outpatient clinic sleep disorders
Published Date 2024-08-09
Publication Title Medicine
Volume volume103
Issue issue32
Publisher Lippincott, Williams & Wilkins
Start Page e39113
ISSN 0025-7974
NCID AA00728867
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 the Author(s).
File Version publisher
PubMed ID 39121265
DOI 10.1097/MD.0000000000039113
Web of Science KeyUT 001287977800045
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000039113
JaLCDOI 10.18926/AMO/67554
FullText URL 78_4_349.pdf
Author Tominaga, Yuichiro| Sugaya, Akiko| Kariya, Shin| Shimizu, Aiko| Kataoka, Yuko| Ando, Mizuo|
Abstract Middle-ear salivary gland choristoma (SGCh) is a rare, benign tumor that causes conductive hearing loss owing to middle-ear morphological abnormalities. Early diagnosis is challenging, and surgical resection is indispensable for a definitive diagnosis. We report the case of a 3-year-old boy diagnosed with middle-ear SGCh during the follow-up period for left-sided hearing loss discovered at newborn hearing screening (NHS). Long-term follow-up after the NHS result, subsequent computed tomography/magnetic resonance imaging, and surgical resection led to its relatively early diagnosis and treatment.
Keywords middle-ear salivary gland choristoma middle-ear morphological abnormalities newborn hearing screening unilateral hearing loss surgical resection
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 349
End Page 355
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198990
Web of Science KeyUT 001310557400004
JaLCDOI 10.18926/AMO/67553
FullText URL 78_4_345.pdf
Author Kato, Gentaro| Narumiya, Yuto| Okuyama, Michihiro| Shimizu, Shuji| Sangawa, Kenji| Yamamoto, Shu|
Abstract The presence of an intraperitoneal source of infection, e.g., a liver abscess, can be an obstacle to performing an abdominal aortic surgery with a midline laparotomy because graft infection is one of the most critical complications of aortic surgery. We report the successful Y-grafting of a pararenal abdominal aortic aneurysm through a retroperitoneal approach in a 67-year-old male undergoing liver abscess drainage. The retroperitoneal approach to the abdominal aorta may be useful for abdominal aortic surgery in patients with a localized intraperitoneal infection.
Keywords blunt liver trauma liver abscess abdominal aortic aneurysm Y-grafting retroperitoneal approach
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 345
End Page 347
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198989
Web of Science KeyUT 001310557400003
JaLCDOI 10.18926/AMO/67550
FullText URL 78_4_337.pdf
Author Makihara, Seiichiro| Otani, Yoshihiro| Uraguchi, Kensuke| Ono, Sawako| Shimizu, Aiko| Ikemachi, Ryosuke| Okazaki, Yosuke| Ota, Tomoyuki| Matsumoto, Hiroshi| Miyamoto, Shotaro| Tsumura, Munechika| Hayashi, Seiya| Umakoshi, Michiari| Hirashita, Koji| Ando, Mizuo|
Abstract Here, we describe the unique case of a pneumocephalus originating from an inverted papilloma (IP) in the frontoethmoidal sinus. A 71-year-old man with diabetes presented with headaches and altered consciousness. Imaging revealed the pneumocephalus together with bone destruction in the left frontal sinus. He underwent simultaneous endoscopic endonasal and transcranial surgery using an ORBEYE exoscope. Pathological diagnosis of the tumor confirmed IP. Post-surgery, the pneumocephalus was significantly resolved and the squamous cell carcinoma antigen level, which had been elevated, decreased. This case underscores the importance of a multidisciplinary approach and innovative surgical methods in treating complex sinonasal pathologies.
Keywords pneumocephalus inverted papilloma frontoethmoidal sinus endoscopic endonasal and transcranial surgery
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 337
End Page 343
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198988
Web of Science KeyUT 001310557400002
JaLCDOI 10.18926/AMO/67549
FullText URL 78_4_331.pdf
Author Furukawa, Chieko| Tachibana, Tomoyasu| Nobuhisa, Tetsuji| Kanie, Yuichiro| Wani, Yoji| Matsumoto, Jun-Ya| Kariya, Akifumi| Sato, Asuka| Ishikawa, Iichiro| Naoi, Yuto| Ando, Mizuo|
Abstract No previous study has published magnetic resonance imaging (MRI) findings for a subglottic pleomorphic adenoma. Here, we describe the case of a 62-year-old man with a subglottic pleomorphic adenoma. Endoscopic findings revealed a smooth-surfaced tumor arising from the subglottic posterior wall. MRI revealed the lesion as an isointense region on T1-weighted images, which was homogeneously enhanced. This lesion showed a heterogeneously hyperintense region on T2-weighted images. Diffusion-weighted imaging (DWI) showed slightly high intensity in the same area, with a normal or only slightly high apparent diffusion coefficient (ADC). Laryngomicrosurgery was performed for transoral excision of the subglottic tumor, resulting in a postsurgical diagnosis of pleomorphic adenoma.
Keywords subglottis pleomorphic adenoma MRI transoral surgery
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 331
End Page 335
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198987
Web of Science KeyUT 001310557400001
JaLCDOI 10.18926/AMO/67548
FullText URL 78_4_323.pdf
Author Katayama, Akira| Kimura, Satoshi| Matsusaki, Takashi| Morimatsu, Hiroshi|
Abstract It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications.
Keywords pediatric liver transplantation postoperative severe complications Graft-to-Recipient Weight Ratio
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 323
End Page 330
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198986
Web of Science KeyUT 001310576400003
JaLCDOI 10.18926/AMO/67547
FullText URL 78_4_313.pdf
Author Eto, Eriko| Maki, Jota| Yamashita, Noriyuki| Hasegawa, Toru| Suemori, Ayano| Nakato, Hikari| Oba, Hikaru| Mitoma, Tomohiro| Mishima, Sakurako| Kirino, Satoe| Ohira, Akiko| Masuyama, Hisashi|
Abstract During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku–Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered “satisfied” or “very satisfied” with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable.
Keywords remote simulator education perinatal simulator information and communication technology high-flexibility education
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 313
End Page 322
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198985
Web of Science KeyUT 001310576400002
JaLCDOI 10.18926/AMO/67546
FullText URL 78_4_307.pdf
Author Sugihara, Naoya| Hashine, Katsuyoshi| Yamashita, Natsumi| Sakamoto, Miki| Terashita, Masato| Funaki, Keisuke| Saiki, Kaori| Sawada, Takatora| Kakuda, Toshio| Nishimura, Kenichi| Fukumoto, Tetsuya| Miura, Noriyosi| Miyauchi, Yuki| Kikugawa, Tadahiko| Saika, Takashi|
Abstract The Briganti nomogram (cut-off value 5%) is commonly used to determine the indications for pelvic lymph node dissection (PLND) in patients with prostate cancer. We retrospectively analyzed the potential oncological benefit of PLND based on the 5% cut-off value on the Briganti nomogram. We obtained the data from the Medical Investigation Cancer Network (MICAN) Study, which included 3,463 patients who underwent a radical prostatectomy (RP) at nine institutions in Japan between 2010 and 2020. We included patients with Briganti scores ≥ 5% and a follow-up period ≥6 months and excluded patients categorized in the very high-risk group (based on NCCN categories); a final total of the cases of 1,068 patients were analyzed. The biochemical recurrence (BCR)-free survival was significantly worse in the patients who underwent PLND compared to those who did not (p=0.019). A multivariate analysis showed that high prostate-specific antigen (PSA) levels (p<0.001) and an advanced T-stage (p=0.018) were significant prognostic factors for BCR, whereas PLND had no effect on BCR (p=0.059). Thus, PLND in patients with prostate cancer whose Briganti score was 5% did not provide any oncological benefit. Further research is necessary to determine the indication criteria for conducting PLND.
Keywords Briganti nomogram pelvic lymph node dissection prostate cancer radical prostatectomy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 307
End Page 312
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198984
Web of Science KeyUT 001310576400001