result 13412 件
| JaLCDOI | 10.18926/bgeou/63237 |
|---|---|
| Title Alternative | Study of the Literary Education Curriculum - Australian Curriculum Consideration Based on “Literature” in English - |
| FullText URL | bgeou_179_037_043.pdf |
| Author | Ukida, Mayumi| |
| Abstract | 本研究の目的は日本の文学教育をカリキュラムの側面から検討することである。日本の学習指導要領の文学・物語に関する指導事項や言語活動例とオーストラリアン・カリキュラム中の「文学」の指導事項を比較する。これまで文学作品の「何をどのように教えるか」に関して考察されてきたが，カリキュラムの側面から考察されることは少なかった。本稿では，文学を読むこととともに，文学・物語の読むこと―書くことをカリキュラムの側面から検討した。その結果，オーストラリアン・カリキュラムから日本のカリキュラムに参考にできる点は①すべての学年で順序性・系統性をもって学習内容を配列すること，②読むこと―書くことの関連指導を行うこと，③修辞技法や文芸批評理論を適切に学習内容に取り入れることである。 |
| Keywords | 学習指導要領 オーストラリアン・カリキュラム 文学教育 |
| Publication Title | Bulletin of Graduate School of Education, Okayama University |
| Published Date | 2022-02-24 |
| Volume | volume179 |
| Start Page | 37 |
| End Page | 43 |
| ISSN | 1883-2423 |
| language | Japanese |
| File Version | publisher |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ueno, Sayaka| Sudo, Tamotsu| Hirasawa, Akira| |
| Keywords | hereditary tumors ATM DNA damage redox homeostasis tumor profiling precision therapy |
| Published Date | 2022-01-04 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | MDPI |
| Start Page | 523 |
| ISSN | 1422-0067 |
| NCID | AA12038549 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35008949 |
| DOI | 10.3390/ijms23010523 |
| Web of Science KeyUT | 000758551600001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms23010523 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Toda, Yuichiro| Wada, Akimasa| Miyase, Hikari| Ozasa, Koki| Matsuno, Takayuki| Minami, Mamoru| |
| Keywords | 3D space perception growing neural gas topological structure learning method |
| Published Date | 2022-02-07 |
| Publication Title | Applied Sciences-Basel |
| Volume | volume12 |
| Issue | issue3 |
| Publisher | MDPI |
| Start Page | 1705 |
| ISSN | 2076-3417 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| DOI | 10.3390/app12031705 |
| Web of Science KeyUT | 000759097000001 |
| Related Url | isVersionOf https://doi.org/10.3390/app12031705 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takeuchi, Noriko| Sawada, Nanami| Ekuni, Daisuke| Morita, Manabu| |
| Keywords | frailty oral diadochokinesis prospective cohort study |
| Published Date | 2022-01-20 |
| Publication Title | International Journal Of Environmental Research and Public Health |
| Volume | volume19 |
| Issue | issue3 |
| Publisher | MDPI |
| Start Page | 1145 |
| ISSN | 1660-4601 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35162167 |
| DOI | 10.3390/ijerph19031145 |
| Web of Science KeyUT | 000760060800001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijerph19031145 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mizuno, Tomofumi| Nishii, Nobuhiro| Morita, Hiroshi| Ito, Hiroshi| |
| Keywords | Transvenous pacemaker Fontan operation Sinus node dysfunction Atrial tachycardia Case report |
| Published Date | 2022-01-13 |
| Publication Title | European Heart Journal-Case Reports |
| Volume | volume6 |
| Issue | issue1 |
| Publisher | Oxford Univ Press |
| Start Page | ytac003 |
| ISSN | 2514-2119 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022. |
| File Version | publisher |
| PubMed ID | 35059560 |
| DOI | 10.1093/ehjcr/ytac003 |
| Web of Science KeyUT | 000753349900033 |
| Related Url | isVersionOf https://doi.org/10.1093/ehjcr/ytac003 |
| FullText URL | fulltext20220302-1.pdf |
|---|---|
| Author | Miyoshi, Shin-ichi| Okubo, Naomi| Mitsumori, Satoko| |
| Keywords | Surfactant Washing detergent Linear alkylbenzene sulfonate Soil bacteria |
| Note | This is the peer reviewed version of the following article: [Miyoshi, S, Okubo, N, Mitsumori, S. Isolation and identification of soil bacteria resistant to surfactants in washing detergents. J Surfact Deterg. 2022; 1– 5. https://doi.org/10.1002/jsde.12587], which has been published in final form at [https://doi.org/10.1002/jsde.12587]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2022-02-11 |
| Publication Title | Journal of Surfactants and Detergents |
| Volume | volume25 |
| Publisher | Wiley |
| Start Page | 521 |
| End Page | 525 |
| ISSN | 1097-3958 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 AOCS. |
| File Version | author |
| DOI | 10.1002/jsde.12587 |
| Web of Science KeyUT | 000754169600001 |
| Related Url | isVersionOf https://doi.org/10.1002/jsde.12587 |
| FullText URL | fulltext20220301-2.pdf |
|---|---|
| Author | Fox, Brian| |
| Keywords | John McGahern Irish literature Irish identity transatlantic literature America and Ireland |
| Note | This is an Accepted Manuscript of an article published by Taylor & Francis in Irish Studies Review on 2022-02-09, available online: http://www.tandfonline.com/10.1080/09670882.2022.2037269| This fulltext is available in Aug. 2023.| |
| Published Date | 2022-02-09 |
| Publication Title | Irish Studies Review |
| Volume | volume30 |
| Issue | issue1 |
| Publisher | Informa UK Limited |
| Start Page | 65 |
| End Page | 81 |
| ISSN | 0967-0882 |
| NCID | AA11862089 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Informa UK Limited |
| File Version | author |
| DOI | 10.1080/09670882.2022.2037269 |
| Web of Science KeyUT | 000753285700001 |
| Related Url | isVersionOf https://doi.org/10.1080/09670882.2022.2037269 |
| FullText URL | fulltext20220301-1.pdf |
|---|---|
| Author | Tokumasu, Miho| Nishida, Mikako| Kawaguchi, Takamasa| Kudo, Ikuru| Kotani, Tohru| Takeda, Kazuhiko| Yoshida, Takao| Udono, Heiichiro| |
| Note | This is a pre-copyedited, author-produced version of an article accepted for publication in International Immunology following peer review. The version of record [Miho Tokumasu, Mikako Nishida, Takamasa Kawaguchi, Ikuru Kudo, Tohru Kotani, Kazuhiko Takeda, Takao Yoshida, Heiichiro Udono, Blocking EP4 downregulates tumor metabolism and synergizes with anti-PD-1 therapy to activate natural killer cells in a lung adenocarcinoma model, International Immunology, 2022;, dxac004, https://doi.org/10.1093/intimm/dxac004] is available online at: https://doi.org/10.1093/intimm/dxac004| |
| Published Date | 2022-2-8 |
| Publication Title | International Immunology |
| Volume | volume34 |
| Issue | issue6 |
| Publisher | Oxford University Press (OUP) |
| Start Page | 293 |
| End Page | 302 |
| ISSN | 1460-2377 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022. Published by Oxford University Press on behalf of The Japanese Society for Immunology. |
| File Version | author |
| DOI | 10.1093/intimm/dxac004 |
| Web of Science KeyUT | 000784781800001 |
| Related Url | isVersionOf https://doi.org/10.1093/intimm/dxac004 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Liu, Yujia| Myojin, Takumi| Li, Kexin| Kurita, Ayuki| Seto, Masayuki| Motoyama, Ayano| Liu, Xiaoyang| Satoh, Ayano| Munemasa, Shintaro| Murata, Yoshiyuki| Nakamura, Toshiyuki| Nakamura, Yoshimasa| |
| Keywords | 3-hydroxyphenylacetic acid aldehyde dehydrogenase quercetin metabolites aryl hydrocarbon receptor acetaldehyde |
| Published Date | 2022-02-03 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume23 |
| Issue | issue3 |
| Publisher | MDPI |
| Start Page | 1762 |
| ISSN | 1422-0067 |
| NCID | AA12038549 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35163684 |
| DOI | 10.3390/ijms23031762 |
| Web of Science KeyUT | 000756270900001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms23031762 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ando, Eri| Nakasuka, Takamasa| Kubo, Toshio| Taniguchi, Akihiko| Ninomiya, Kiichiro| Kato, Yuka| Ichihara, Eiki| Ohashi, Kadoaki| Rai, Kammei| Hotta, Katsuyuki| Yamane, Masaomi| Miyahara, Nobuaki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki| |
| Keywords | pulmonary aspergilloma allergic bronchopulmonary aspergillosis disaster |
| Published Date | 2022-02-01 |
| Publication Title | Internal Medicine |
| Volume | volume61 |
| Issue | issue3 |
| Publisher | JAPAN SOC INTERNAL MEDICINE |
| Start Page | 379 |
| End Page | 383 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 34373373 |
| DOI | 10.2169/internalmedicine.7124-21 |
| Web of Science KeyUT | 000752787300015 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.7124-21 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ishida, Tomoharu| Hagiya, Hideharu| Honda, Hiroyuki| Nakano, Yasuhiro| Ogawa, Hiroko| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Hanayama, Yoshihisa| Otsuka, Fumio| |
| Published Date | 2021-11-12 |
| Publication Title | Plos One |
| Volume | volume16 |
| Issue | issue11 |
| Publisher | Public Library Science |
| Start Page | e0259633 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Ishida et al. |
| File Version | publisher |
| PubMed ID | 34767587 |
| DOI | 10.1371/journal.pone.0259633 |
| Web of Science KeyUT | 000755249300037 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0259633 |
| JaLCDOI | 10.18926/AMO/63222 |
|---|---|
| FullText URL | 53_3_141.pdf |
| Author | Nagata, Hiroshi| Ohta, Takeo| Aoyama, Hideyasu| |
| Abstract | Medical students (fourth-year: n = 67; fifth-year: n = 63) estimated inpatients' feelings of anxiety, self-esteem, purpose-in-life, and multidimensional health locus of control. Their ratings were compared both with the ratings given by the 121 inpatients themselves and with those given by nursing practitioners (nurses and nursing students). Findings showed that the medical students overestimated inpatients' anxiety, while they underestimated the inpatients' purpose-in-life and internal health locus of control. Hence they underestimated, as did the nursing practitioners, the inpatients' positive emotional states and their positive attitude toward their own lives. Fifth-year medical students, with clinical experience, rated the inpatients' score of chance health locus of control higher than did the fourth-year medical students, who had no clinical experience. These findings indicate that medical students, like nursing practitioners, are inclined to pay more attention to inpatients' weaknesses than to their strengths. |
| Keywords | inpatient's mental health anxiety self-esteem purpose-in-life health locus of control |
| Amo Type | Brief Note |
| Publication Title | Acta Medica Okayama |
| Published Date | 1999-06 |
| Volume | volume53 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 141 |
| End Page | 145 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 1999 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 10410792 |
| Web of Science KeyUT | 000081201100007 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Umebayashi, Ryoko| Uchida, Haruhito Adam| Matsuoka-Uchiyama, Natsumi| Sugiyama, Hitoshi| Wada, Jun| |
| Keywords | chronic kidney disease medical checkup risk factor |
| Published Date | 2022-01-12 |
| Publication Title | Journal Of Personalized Medicine |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | MDPI |
| Start Page | 97 |
| ISSN | 2075-4426 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35055412 |
| DOI | 10.3390/jpm12010097 |
| Web of Science KeyUT | 000757349900001 |
| Related Url | isVersionOf https://doi.org/10.3390/jpm12010097 |
| JaLCDOI | 10.18926/AMO/63219 |
|---|---|
| FullText URL | 76_1_99.pdf |
| Author | Naito, Yoichiro| Yoshikawa, Masaki| Nakamura, Kazufumi| Kubo, Motoki| Sugiyama, Hiroyasu| Suzuki, Hideyuki| Fujita, Shinpei| Arai, Yasunori| Takahashi, Sho| Kato, Yuichi| Yoshida, Yu| Akai, Hiroaki| Murakami, Shuhei| Ito, Hiroshi| |
| Abstract | Rapidly progressive in-stent restenosis (ISR) after stent deployment from the left main trunk (LMT) to the left anterior descending artery (LAD) without plaque at the LMT ostium has not been reported. A 60-year-old Japanese man with a history of scleroderma, pulmonary fibrosis, and type 2 diabetes developed acute myocardial infarction of the right coronary artery (RCA) and was treated by emergency percutaneous coronary intervention (PCI) for RCA. Nine days later he underwent PCI from the LMT to the LAD. Follow-up coronary angiography (CAG) at 9 and 21 months post-PCI did not reveal ISR in any lesion, but the patient experienced cardiac arrest at 25 months post-PCI. Emergency CAG after resuscitation revealed ISR of the LMT ostium; emergency PCI was conducted. The development of ISR at the ostium of the LMT although the patient was free of plaque 4 months before is extremely unusual. This rare ISR of the LMT ostium progressed rapidly after follow-up CAG revealed no ISR at 21 months post-stent implantation. |
| Keywords | left main trunk in-stent restenosis cardiopulmonary arrest |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 99 |
| End Page | 104 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237006 |
| Web of Science KeyUT | 000762933000003 |
| JaLCDOI | 10.18926/AMO/63218 |
|---|---|
| FullText URL | 76_1_93.pdf |
| Author | Ishi, Yukitomo| Yamaguchi, Shigeru| Hatanaka, Kanako C.| Takakuwa, Emi| Motegi, Hiroaki| Honda, Taishi| Kobayashi, Hiroyuki| Terasaka, Shunsuke| Homma, Akihiro| Fujimura, Miki| Houkin, Kiyohiro| |
| Abstract | A 66-year-old man underwent multimodal treatment for olfactory neuroblastoma (ONB). When he was 72 years old, a cystic intracranial lesion without accumulation on fluorine-18-fluorodeoxyglucose positron emission tomography was detected. Surgical resection was performed when the patient was 73 years old. The pathological examination revealed recurrence of ONB, and the patient underwent focal irradiation. At age 81, he presented with a second recurrence in the right occipital lobe with radiological and pathological findings similar to the prior recurrence. This case suggests that pathological confirmation should be considered in cases with atypical radiological findings following the treatment of ONB. |
| Keywords | cystic recurrence esthesioneuroblastoma fluorine-18-fluorodeoxyglucose positron emission tomography intracranial recurrence olfactory neuroblastoma |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 93 |
| End Page | 98 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237005 |
| Web of Science KeyUT | 000762933000002 |
| JaLCDOI | 10.18926/AMO/63217 |
|---|---|
| FullText URL | 76_1_89.pdf |
| Author | Ryuko, Tsuyoshi| Yamamoto, Hiromasa| Sugimoto, Seiichiro| Suzawa, Ken| Miyoshi, Kentaroh| Otani, Shinji| Okazaki, Mikio| Yamane, Masaomi| Toyooka, Shinichi| |
| Abstract | Congenital lobar emphysema (CLE) is defined as the hyperinflation of pulmonary lobes due to obstruction of the flow of air via a known or unknown etiology, which causes pressure symptoms in the adjacent organs. CLE is mainly diagnosed in the neonatal period, and very few adult cases have been reported. Here we report a 34-year-old male with muscular dystrophy who was diagnosed with CLE on examination. He underwent a right lower lobectomy via 3-portal completely video-assisted thoracoscopic surgery, and his symptoms improved. Thoracoscopic surgery helped preserve the respiratory muscles and led to the improvement of respiratory function in this patient. |
| Keywords | congenital lobar emphysema, adult, lobectomy, completely video-assisted thoracoscopic surgery, muscular dystrophy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 89 |
| End Page | 92 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237004 |
| Web of Science KeyUT | 000762933000001 |
| JaLCDOI | 10.18926/AMO/63216 |
|---|---|
| FullText URL | 76_1_85.pdf |
| Author | Omi, Hirotsugu| Tomita, Takashi| Ichinohe, Masayuki| Harada, Yoshifumi| Sato, Hideki| Ito, Junji| |
| Abstract | A 75-year-old woman underwent L4-L5 lateral interbody fusion for L4-5 foraminal stenosis with the use of percutaneous pedicle screws. On the day after the surgery, she was in shock. Emergency contrast-enhanced CT showed active extravasation from the 4th lumbar artery with a transverse process fracture. A radiologist performed a successful transarterial embolization, and the patient then began walking training on the 4th day post-surgery. Close attention should be paid to the insertion of a percutaneous pedicle screw, as it may cause a lumbar artery injury; in such a case, transarterial embolization is the preferred treatment. |
| Keywords | lumbar artery injury percutaneous pedicle screw transverse process fracture hematoma |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 85 |
| End Page | 88 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237003 |
| Web of Science KeyUT | 000762803800003 |
| JaLCDOI | 10.18926/AMO/63215 |
|---|---|
| FullText URL | 76_1_79.pdf |
| Author | Tokumoto, Kana| Mino, Takuya| Kurosaki, Yoko| Izumi, Koji| Maekawa, Kenji| Nakano, Tomohito| Sejima, Junichi| Ueda, Akihiro| Kimura-Ono, Aya| Hyung Kim, Tae| Kuboki, Takuo| |
| Abstract | We introduce a new digital workflow to fabricate a fixed partial denture (FPD) utilizing the three-dimensional surface morphology of provisional restoration (PR) and abutment teeth. Scanned images of the full maxilla with abutment teeth, full maxilla with PR, and PR alone were superimposed. The surfaces of the final FPD were designed based on the entire morphology of the PR and abutment teeth surfaces. The inner and outer surfaces converged at the margin lines of the abutment teeth. Fine modifications to the final FPD design were performed manually, and the final FPD was fabricated and successfully installed in the patient. |
| Keywords | prosthodontics computer-aided design digital dentistry fixed partial denture dental restoration |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 79 |
| End Page | 84 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237002 |
| Web of Science KeyUT | 000762803800002 |
| JaLCDOI | 10.18926/AMO/63214 |
|---|---|
| FullText URL | 76_1_71.pdf |
| Author | Tanaka, Masato| Sonawane, Sumeet| Fujiwara, Yoshihiro| Uotani, Koji| Arataki, Shinya| Yamauchi, Taro| Ye, Youchen| Misawa, Haruo| |
| Abstract | The surgical treatment of pediatric atlantoaxial subluxation (AAS) in Down syndrome (DS) remains technically challenging due to radiation exposure and complications such as vertebral artery injury and nonunion. The established treatment is fixation with a C1 lateral mass screw and C2 pedicle screw (modified Goel technique). However, this technique requires fluoroscopy for C1 screw insertion. To avoid exposing the operating team to radiation we present here a new C-arm free O-arm navigated surgical procedure for pediatric AAS in DS. A 5-year-old male DS patient had neck pain and unsteady gait. Radiograms showed AAS with an atlantodental interval of 10 mm, and irreducible subluxation on extension. CT scan showed Os odontoideum and AAS. MRI demonstrated spinal cord compression between the C1 posterior arch and odontoid process. We performed a C-arm free O-arm navigated modified Goel procedure with postoperative halo-vest immobilization. At oneyear follow-up, good neurological recovery and solid bone fusion were observed. The patient had no complications such as epidural hematoma, infection, or nerve or vessel injury. This novel procedure is a useful and safe technique that protects surgeons and staff from radiation risk. |
| Keywords | atlantoaxial fixation Down syndrome C-arm free O-arm navigation surgery modified Goel technique |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 71 |
| End Page | 78 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237001 |
| Web of Science KeyUT | 000762803800001 |
| JaLCDOI | 10.18926/AMO/63213 |
|---|---|
| FullText URL | 76_1_63.pdf |
| Author | Zhang, Bei| Pei, Zhixin| Wang, Hongxia| Wu, Huimin| Wang, Junjie| Bai, Junjun| Song, Qinglin| |
| Abstract | We analyzed the treatment effects of chidamide and decitabine in combination with a HAG (homoharringtonine, cytarabine, G-CSF) priming regimen (CDHAG) in acute myeloid leukemia (AML) patients with TP53 mutation. Seven TP53 mutated AML patients were treated with CDHAG. The treatment effects were assessed using hemogram detection and bone marrow aspirate. The possible side effects were evaluated based on both hematological and non-hematological toxicity. Four of the seven patients were classified as having achieved complete remission after CDHAG treatment; one patient was considered to have achieved partial remission, and the remaining two patients were considered in non-remission. The overall response rate (ORR) to CDHAG was 71.4%. Regarding the side effects, the hematological toxicity level of the seven patients ranged from level III to level IV, and infections that occurred at lung, blood, and skin were recorded. Nausea, vomiting, liver injury, and kidney injury were also detected. However, all side effects were attenuated by proper management. The CDHAG regimen clearly improved the ORR (71.4%) of TP53-mutated AML patients, with no severe side effects. |
| Keywords | acute myeloid leukemia chidamide decitabine HAG TP53 mutation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 63 |
| End Page | 70 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237000 |
| Web of Science KeyUT | 000762812700009 |
