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Author 岡山大学温泉研究所|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Oshima, Yoshio|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Seki, Masaji|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 大島 良雄|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 淸水 多栄|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Institute for Thermal Spring Research, Okayama University|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1954-03
Publication Title 岡山大学温泉研究所報告
Volume volume14
Content Type Others
JaLCDOI 10.18926/40332
Title Alternative MEDICAL STUDIES ON THE RURAL PEOPLE (II) A STUDY ON THE INCIDENCE OF STRUMA IN THE SOUTH-WESTERN RURAL DISTRICTS OF OKAYAMA PREFECTURE, JAPAN
FullText URL pitsr_014_051_056.pdf
Author Morinaga, Hiroshi|
Abstract The author investigated the thyroid glands of 1480 school children (aged from 6 to 14) living in the vicinity of Yakage, the south-western rural district of Okayama Prefecture, and 1516 out-patients of Yakage Hospital, in 1950. The incidence of struma among the school children was 4.6 per cent and among the out-patients 4.7% on an average, and the percentage of struma in the spring (7.8%) was higher than in the summer (2.98%). This result suggests that thyroid glands are in some way susceptible to seasonal influences, and it is therefore necessary to consider the effect of season during investigation. The white blood pictures of seven patients showed no specific findings.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 51
End Page 56
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002462907
JaLCDOI 10.18926/40331
Title Alternative MEDICAL STUDIES ON THE RURAL PEOPLE (I) CLINICAL AND STATISTICAL OBSERVATIONS ON HOOKWORM DISEASE IN RURAL DISTRICTS
FullText URL pitsr_014_045_050.pdf
Author Morinaga, Hiroshi|
Abstract The author studied statistically 160 cases of hookworm infection who had been admitted to Misasa Branch of Okayama University Hospital, Misasa Hot Springs in Tottori prefecture, during 1946~1949 and 162 cases of out-patients with anchylostomiasis in Yakage Hospital, Okayama Prefecture, during 1949~1950. The clinical findings were as follows: (1). Females showed a higher incidence than males and the incidence ratio of infected persons to total out-patients increased with age up to the 50~69 years group. (2). The most patients consulted our hospital for the first time in April~May and in August, and 62 per cent of cases came within 3 months scince they had noticed disorders in some way, but 22% remained at home without medical cure more than a year. (3). Chief subjective complaints were palpitation of heart (35.3%), lassitude of legs (31.2%), pains in the abdomen (22.9%), feeling of dizziness (21.6%) and so on. (4). Laboratory findings: The total number of erythrocytes was between 1.23 and 5.54 millions per cubic millimeter and a moderate anemia almost always developed in the hookworm disease (77.9% of all cases). The number of white cells was normal or slightly increased. Relative or absolute eosinophilia was recognized in 83.5% of all patients. Wassermann's test was positive in 20%, and Takata's reaction positive in 53% of the cases. The acidity of the gastric juice was lower than normal. Hypo- and anacidity were verified in 58%. Both albumen and urobilinogen test in urine were positive in 5.4% of 61 cases. Sugar in none. (5). Treatment: Thymol, tetrachlorethylene and oil of chenopodium were used alternately to remove the worms. The eggs in stool became negative after 3-4 times of the administration of anthelmintics in 76 per cent of 151 cases. As mentioned above, the patients infected with hookworm had various functional disorders of bodies, but they consulted the hospital only when the farmer's busy season began and their trouble became unbearable. And then the recovery of anemia took a month or two. Prof. Kitayama reported that the cold environment under 9°C. in the winter had perished the larva of hookworm in the soil. From these viewpoints, the author proposed that examination and cure of hookworms should be carried out in the winter, the slack season for farming, to prevent the fall of working ability due to anchylostomiasis during the busy farming seasons.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 45
End Page 50
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40330
language Japanese
File Version publisher
NAID 120002462906
Author 岡山大学温泉研究所|
Published Date 1954-03
Publication Title 岡山大学温泉研究所報告
Volume volume14
Content Type Others
JaLCDOI 10.18926/40329
Title Alternative DIE ERFAHRUNGEN VON GYNEKOLOGISCHEN BALNEOTHERAPIE (5) DER EINFLUSS VON ORALEN ANWENDUNG VON THERMALWASSER AUF DIE LEBERFUNKTION VON SCHWANGEREN FRAU
FullText URL 014_038_044.pdf
Author Hasegawa, Yasumasa|
Abstract Nach oraler Anwendung vom kochsalzhaitigen schwach radioaktiven Thermalwasser von MISASA 500 ccm bei 20 schwangeren Frauen (meistens S. S. IIM. bis S. S. IVM.) wurden die folgneden Untersuchungen über Leberfunktionen angestellt und mit dem Resultat nach oralen Anwendung von Süsswasser verglichen. 1) Das Thermalwasser steigerte die Zusammensetzungsfähigkeit von Hippursäure d. h· Entgiftungsfähigkeit von Leber. 2) Nach Asorbin S Methode erwies sich keine Veränderung. 3) Die Aussheidungsfähigkeit von Bromsulfalein wurde schwach. 4) 4 stundige Harnmenge nach den oralen Anwendung war weniger bei dem Thermalwasser als bei Süsswasser, und NaCl Menge in beiden Harn war gleich. In Rücksicht auf oben genannten Untersuchungen, trotz des speziellen Einflusses auf die Leberfunktion, wegen antidiuretischer Wirkung darf orale Anwendung des Thermalwassers von MISASA bei schwangeren Frau nur mit einer gewissen Vorsicht gemacht werden.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 38
End Page 44
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532463
JaLCDOI 10.18926/40328
Title Alternative KLINISCHE UND EXPERIMENTELLE UNTERSUCHUENGN ÜBER DIE WIRKUNG VON THERMALBÄDERN AUF DIE SEXUALFUNKTION VON FRAUEN (6) KONSCHE SILBERREAKTION VON HYPOPHYSEN-HYPOPHYSEN VORDERLAPPEN, OVARIUM UND NEBENNIERE VON RATTE UND DAS THERMALBAD
FullText URL pitsr_014_033_037.pdf
Author Tanaka, Yosinori| Hasegawa, Yasumasa|
Abstract Konsche Siberreaktion (Kon : Silberreaktion der Zellen - Gustav Fischer) ist eine histochemische methode für den Nachweis der Reduktionskraft der Zellen, die von Professor Kon erfunden wurde und im Zusammenhang mit Vitalität der Zellen besonders der endokrinen Organe steht. Also bedeutet die starke Offenbarung dieser Reaktion die gesteigerte Funktion der Gewebe. Um zu forschen ob die geschlechtsfunktion durch Thermalbad beeinflusst wurde, wurde diese Reaktion auf die Hypophysenvorderlappen, Ovarium und Nebenniere der Ratte nach Thermalbad (schwach radioaktive Therme und H2S Therme, 42°C, 5 Minuten lang) angewandt. Sofort nach einmaligem Bad handelte es sich kein Unterschied zwischen Badgruppe und Komtrollgruppe. Nach eimal täglich 50 tägigen Btidern verstaerkte sich die Reaktion von Hypophysenvorderlappen und Corpus luteum von Ovarium (besonders bei H(2)S Therme) aber in anderer Gewebe befand keine Veraenderung sich. Also ist es klar, dass Funktion von Hypophysenvorderlappen und Ovarium nach wiederholten Thermalbaedern sich steigert.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 33
End Page 37
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002462905
JaLCDOI 10.18926/40327
Title Alternative THE EFFECT OF THERMAL BATHS UPON THE ETHER-EJACULATION IN ALBINO RATS
FullText URL pitsr_014_030_032.pdf
Author Okada, Toshio|
Abstract The rate of ejaculation induced by ether narcosis in adult male albino rats increased after the serial thermal baths of Misasa (at 42°C for 5 minutes) during 3 weeks. No remarkable difference was shown concerning the above-mentioned actions between the weakly and the strongly radioactive spring.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 30
End Page 32
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002462904
JaLCDOI 10.18926/40326
Title Alternative ASOZU (WEAK COMMON SALT SPRING), HAMAMURA (SULPHATED BITTER SPRING), KAlKE (CALCIUM CHLORIDE CONTAINING SALINE SPRING) AND FUJINO (ACID ALUM VITRIOL SPRING) SPRING WATERS AND THE ALIMENTARY HYPERGLYCEMIA
FullText URL pitsr_014_022_029.pdf
Author Morinaga, Hiroshi|
Abstract There are many experimental reports and clinical observations about the internal use of thermal waters on carbohydrate metabolism, and alkaline springs, alkaline common salt springs and sulphur springs are used for the balneological therapy of diabetic patients. The author reported that the internal use of the radon springs of Japan, such as Misasa, Ikeda and Masutomi thermal waters promoted the action of insuline and inhibited the experimental hyperglycemia in rabbits, and he suggested that these radioactive waters also would be able to utilize for the diabetic treatment. On the other hand, trace elements such as Cu, Zn and Mn have protective effects against disturbed carbohydrate metabolism of diabetic body. Some thermal waters contain these trace elements in various degrees, and Oshima & Ashizawa observed that after the drinking of Fujino mineral water the iron, copper, nickel and cobalt content in blood rose temporarily. In this report, the author investigated the influence of the drinking of Asozu (weak common salt spring), Hamamura (sulphated bitter spring), Kaike (calcium chloride containing saline spring) and Fujino (acid alum vitriol spring) Spring waters upon the alimentary hyperglycemia in rabbits. Thirty ml. of 10% glucose solution in thermal water (Fujino Water was diluted twice with plain water) or in plain water per kg. of bodyweight was administered to the rabbit by stomach tube and blood sugar level was determined before, 1/2, 1, 2, 3 and 4 hours after the administration. The results were as follows: 1. The drinking of Asozu Spring water inhibited the alimentary hyperglycemia compared with the plain water as a control. 2. Hamamura Spring had a tendency to decrease the blood sugar level. 3. Kaike Spring water had no inhibitory a.ction upon the alimentary hyperglycemia. 4. In spite of the existence of trace elements, Fujino mineral water had no significant effect. The author supposed that this was due to its high acidity.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 22
End Page 29
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002462903
JaLCDOI 10.18926/40325
Title Alternative EFFECT OF WATER LEVEL OF RIVER ON MINERAL SPRING
FullText URL pitsr_014_015_021.pdf
Author Umemoto, Shunji|
Abstract From June 1953 to January 1954, the water temperature and amount of flow of a spring called IITanaka-no-Yu", Misasa Hot Springs, Tottori Prefecture, were observed continuously. It issues 10 metres north of the riverside of the River Misasa and a stream runs 3 metres south of it. The water level of the River and the stream were also observed. The water level of the stream have close connection with the water volume of rice-field which surround that spring, because it is a watercourse of irrigation to rice-field. It was found that when the amount of flow increased, the water temperature rose, namely there was a positive correlation between them, and the correlation coefficient was 0.952 (highly significant). The analysis of variance showed that the amount of flow would be affected by the water level of the River but would not be severely affected by that of the stream. The correlation between the amount of flow and the water level of the River was also positive and the correlation coefficient was 0.731 (highly significant). As a result of the analysis of variance, the computation of confidence limit and the analysis of covariance, in summer the averages of the amount of flow and the water temperature would be higher than those in autumn and winter. This difference was seemed to be induced by the water level of the stream. The end of the observation, a dam had been constructed 20 metres down (west) the River and she rised, but the effect of it must be observed after this.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 15
End Page 21
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002462902
JaLCDOI 10.18926/40324
Title Alternative RADON CONTENT OF HOT SPRINGS IN TOTTORI PREFECTURE, JAPAN
FullText URL 014_001_014.pdf
Author Oshima, Yoshio| Yamada, Naoharu| Mifune, Masaaki|
Abstract 1. Radon content of 166 thermal waters in IWAI, TOTTORI YOSHIOKA, HAMAMURA, TOGO, SEKIGANE, MISASA, and KAlKE Hot Springs was measured by I. M. Fontactoscope in the years 1950-1951. Of which 66 samples showed a radon content over 30×10(-10) curie units per liter. Namely, 50 springs in Misasa, 6 in Sekigane, 9 in Hamamura, and one in Togo belonged to the radioactive spring in the definition by Ministry of Social Welfare. The highest Radon content (1150×10(10) curie units per liter) was recorded in Hisuino-Yu in Misasa, where five springs had a radon content over 360×10(-10) curie units per liter. 2. No marked difference was proved between the results obtained this time and the data in the former reports concerning the radon content of these thermal springs. 3. Radon content proved higher in the springs which issue from granite than in the springs of other districts. No definite relation was proved between the radon content and water temperature. The radon content was generally high in simple thermals or in weak sodium chloride springs, low in sulfated springs and in saline springs which had a comparatively high sulfate content.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 1
End Page 14
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532457
Author 岡山大学温泉研究所|
Published Date 1954-03
Publication Title 岡山大学温泉研究所報告
Volume volume14
Content Type Others
JaLCDOI 10.18926/40322
Title Alternative THE CLINICAL STUDIES OF RHEUMATOID ARTHRITIS (I)
FullText URL 016_035_048.pdf
Author Morinaga, Hiroshi|
Abstract The value of spa treatment of rheumatic disease is an established feature of medical management based on experiences for many centuries. The author has been practising the balneotherapy of rheumatic diseases at Misasa Spa for several years, and has found this therapy efficacious in many cases in relieving the anemia that accompanies rheumatoid arthritis. For this reason, the author is investigating the metabolism of iron in rheumatic anemia, which is expected to occur in the course of the spa treatment. In this report, the results of clinical examinations of 24 patients with rheumatoid arthritis, of the type (2. 2. 2.) Polyarthritis systemica chronica (in Prof. Kodama's classification of arthritis), are described. I. Some observations of anemia in rheumatoid arthritis 1. The peripheral blood The number of erythrocytes is 266×10(4)~455×10(4)/c. mm. (average: (381±32)×10(4)/c. mm.), Hb-content : 55~90% (average : 76±5.8%), and the color index is about 1.0. The anemia of rheumatic disease treated is mostly normochromic. The white blood count is between 3240 and 13300/c. mm. (average: 6421±955/c. mm. ), and the number of the leucocytes in 80% of the cases ranges within the normal limits. Eosinophilia is observed in 15% of the cases. 2. Anemia-producing substance in the serum of rheumatoid arthritis When serum from rheumatoid arthritis patients was injected into rabbits, the number of erythrocytes and the hemoglobin -content of the rabbits was found to decrease markedly for 2~6hours after the injection. But no such effect was observed when the serum of healthy subjects was injected. From this, the author presumes the presence of an anemia-producing substance in the serum of rheumatoid arthritis. The nature of this substance in now under investigation. II. Clinical-biochemical studies 3. Gastric acidity of rheumatic patients Of 7 cases examined, anacidity of gastric juice was observed in 2 cases, subacidity in other 2 cases and normacidity in the remaining 3 cases. Thus, a decrease in the gastric acidity was found to occur in 57% of the cases. 4. Takata-serum-test and sedimentation rate It is said that the sedimentation rate and the Weltmann-reaction are very sensitive indicators of the extent of the activity of rheumatic disease. The Takata-serum-test was applied in 18 cases and was found to give positive results in 10 cases (55%). The sedimentation rate was found to increase in 17 of 20 cases (85%). 5. Blood uric acid As is well known, the concentration of uric acid is abnormally high in the blood of patients with gout; while, according to the literature, the blood uric acid levels of patients with rheumatoid arthritis range within the normal limits. The author, using the method of Benedict, obtained the following results for blood uric acid in 14 normal subjects in fasting state: Range - 2.30~3.47mg./dl. , 5% rejection limit -- 1.97~3.68mg./dl. In 5 of 7 cases of rheumatoid arthritis, the blood uric acid levels were shown to be above the upper limit of the normal range, but the concentrations of blood uric acid of non-rheumatic joint diseases and neuralgias were mostly within the normal range. 6. Blood sugar The fasting blood sugar levels of rheumatoid patients ranged from 82 to 1l0mg./dl. (average : 100mg./dl.), higher than the levels of healthy subjects (78~108mg./dl., average : 90mg./dl.). The intravenously injected glucose load test was applied to 8 rheumatoid patients. A solution of 40 ml. of 20% glucose was injected into a fasting subject for 2 minutes. Blood samples were taken before the injection, 3 minutes after the injection, and at each subsequent 10 minute-interval for 70 minutes. The glucose tolerance curves in 5 of these cases were found to be out of the normal range. It is to be noticed that the average blood sugar for rheumatoid arthritis is similar to the curve for liver disease. 7. Serum alkaline phosphatase activity and serum phosphorus The method of Taussky-Shorr was used for the determination of the level of alkaline phosphatase activity and inorganic phosphate in the serum. The alkaline phosphatase activity of 11 normal individuals ranged from 1.4 to 6.4 Shinowara-Jones-Rheinhart units/dl. (5% rejection limit), while in 4 of 8 cases of rheumatoid arthritis, it was of abnormally high levels. The concentration of inorganic phosphate in the serum of 12 normal subjects ranged from 2.9 to 5.0mg. /dl. (5% rejection limit), while in 3 cases of rheumatoid patients, it showed higher levels than normal. 8. Total cholesterol in serum The total cholesterol in the serum of fasting normal individuals was measured by Bloor's method, and the concentration was found to range from 124 to 188mg./dl. (rejection limit of 5% level of significance), and the total cholesterol in the serum of rheumatoid arthritis to be abnormally high in concentration in 6 of 7 cases. The liver function was evaluated by the Takata-serum-test, the test of fasting blood sugar levels, the glucose load test, and the test of serum alkaline phosphatase activity; and from this the hepatic dysfunction was found to occur in rheumatoid arthritis patients in about 50% of the cases examined. Disturbances in the protein, fat, and carbohydrate metabolism were also found to occur. The above-mentioned findings indicate that rheumatoid arthritis is not only a disease of the joints, but also a general and systemic illness. Attention must accordingly be given to the general condition of the patient in the treatment of rheumatic disease.
Publication Title 岡山大学温泉研究所報告
Published Date 1956-01
Volume volume16
Start Page 35
End Page 48
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40318
language Japanese
File Version publisher
NAID 40017532470
JaLCDOI 10.18926/40321
Title Alternative SEASONAL VARIATION OF GASTRIC ACIDITY
FullText URL pitsr_016_031_034.pdf
Author Morinaga, Hiroshi|
Abstract Since, in Japan situated in the temperate zone, climatic change through the four seasons of a year is regular, it is expected that there the physiological reactions of the human body may vary regularly in accordance with the climatic change. In fact, we experience that the attacks of diseases and their conditions are in close connection with the changes of the seasons. The author investigated the effect of the seasons upon the human gastric acidity, by means of the coffein-test, in 580 cases with gastrointestinal disorders, at the Misasa Branch Hospital of Okayama University, Misasa Spa in Tottori Prefecture, in 1946~1946. Hyperacidity was verified in 194 (33%) of 580 cases, normacidity in 134 (23%), anacidity in 138 (24%) and hypacidity in 114 (20%). The percentage of hyperacidity increases in winter (41%), decreases in spring (32%) and in summer (28%), and increases again in autumn (34%). The cases of anacidity decrease in winter and spring, but increase in summer. In chi-square test, the season and the acidity of gastric juice were taken as factors of variation. The chi-square was computed with the result: Pr {X(3)=14.013<16.919} =5%, so it cannot be asserted that the seasonal changes effect the acidity of gastric juice. But if Comparison is made between summer and winter with respect to the anacidity-hypacidity vs. the hyperacidity, the author: obtains Pr {X(2)=6.06> 5.412} =2%. It is thus verified that the cases of hyperacidity predominate over those of anacidity-hypacidity in winter, while the relation is reverse in summer. As was mentioned above, the tendency is obvious that the acidity of gastric juice decreases in summer and increases in winter. It was found that there is a regular seasonal variation in gastric acidity.
Publication Title 岡山大学温泉研究所報告
Published Date 1956-01
Volume volume16
Start Page 31
End Page 34
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40318
language Japanese
File Version publisher
NAID 120002462901
JaLCDOI 10.18926/40320
Title Alternative ANEMIA-PRODUCING SUBSTANCE IN RHEUMATOID ARTHRITIS
FullText URL pitsr_016_019_030.pdf
Author Kishida, Senzo|
Abstract The anemia that usually accompanies rheumatoid arthritis has been thought to be caused by an infection of unknown etiology. The author found from his experiment that a temporary anemia is caused in rabbits by the injection of the serum of patients with rheumatoid arthritis into them, but no such effect by the injection of the serum of healthy subjects. The author presumes the existance of an anemia-producing substance in the serum of the rheumatoid arthritis. The nature of this substance is now under investigation.
Publication Title 岡山大学温泉研究所報告
Published Date 1956-01
Volume volume16
Start Page 19
End Page 30
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40318
language Japanese
File Version publisher
NAID 120002462900