| ID | 62789 |
| FullText URL | |
| Author |
Hisano, Hiroshi
Institute of Plant Science and Resources, Okayama University
ORCID
Kaken ID
publons
researchmap
Abe, Fumitaka
Institute of Crop Science, National Agriculture and Food Research Organization
Hoffie, Robert E.
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)
Kumlehn, Jochen
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)
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| Abstract | The recent advent of customizable endonucleases has led to remarkable advances in genetic engineering, as these molecular scissors allow for the targeted introduction of mutations or even precisely predefined genetic modifications into virtually any genomic target site of choice. Thanks to its unprecedented precision, efficiency, and functional versatility, this technology, commonly referred to as genome editing, has become an effective force not only in basic research devoted to the elucidation of gene function, but also for knowledgebased improvement of crop traits. Among the different platforms currently available for site-directed genome modifications, RNA-guided clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) endonucleases have proven to be the most powerful. This review provides an application-oriented overview of the development of customizable endonucleases, current approaches to cereal crop breeding, and future opportunities in this field.
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| Keywords | barley
CRISPR
maize
rice
TALEN
wheat
zinc-finger nucleases
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| Note | 出典：Breeding Science 71(4) 405-416, 2021 https://doi.org/10.1270/jsbbs.21019
許可を得て出版社版を登録しています。
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| Published Date | 2021-10-01
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| Publication Title |
Breeding Science
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| Volume | volume71
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| Issue | issue4
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| Publisher | Japanese Society of Breeding
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| Start Page | 405
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| End Page | 416
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| ISSN | 1344-7610
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| Content Type |
Journal Article
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| language |
English
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| OAI-PMH Set |
岡山大学
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| Copyright Holders | (C) 2021 Japanese Society of Breeding
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| File Version | publisher
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| DOI | |
| Related Url | isVersionOf https://doi.org/10.1270/jsbbs.21019
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| Citation | Hiroshi Hisano, Fumitaka Abe, Robert E. Hoffie, Jochen Kumlehn, Targeted genome modifications in cereal crops, Breeding Science, 2021, Volume 71, Issue 4, Pages 405-416
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