result 22850 件
JaLCDOI | 10.18926/AMO/68360 |
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FullText URL | 79_1_039.pdf |
Author | Takao, Shinichiro| Uotani, Koji| Misawa, Haruo| Tetsunaga, Tomoko| Shinohara, Kensuke| Yamane, Kentaro| Oda, Yoshiaki| Tsuji, Hironori| Kajiki, Yuya| Ozaki, Toshifumi| |
Abstract | Evaluating vertebral bone mass and quality in the elderly poses challenges due to degenerative changes. This study aims to elucidate the usefulness of the trabecular bone score (TBS) by examining the relationship between bone mineral density (BMD), TBS, and Hounsfield unit (HU) values. A retrospective analysis of 599 vertebrae from 152 patients (mean age 69.0 years; range 44-89; 74 males and 78 females) undergoing dual-energy X-ray absorptiometry (DXA) and CT scans was conducted. Vertebrae were categorized into three grades based on the degree of degeneration. The TBS was calculated from DXA images, and the HU value was measured by placing a region of interest on an axial image of the vertebral mid-body. One-way analysis of variance and Pearson’s correlation tests were employed to investigate the relationship between BMD and TBS or HU values. While lumbar BMD significantly increased (p<0.01) with degenerative changes, TBS and HU values showed no significant differences. The correlations between lumbar BMD and TBS values, and between BMD and HU values, were stronger without degenerative changes than with degenerative changes. Significantly different HU values were observed between the right and left sides of severely degenerated vertebrae. Severe degenerative changes, particularly those associated with sclerosis, may impact HU values. TBS exhibits greater potential than HU values as a complementary tool. |
Keywords | trabecular bone score computed tomography Hounsfield unit lumbar degenerative change radiodensity |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-02 |
Volume | volume79 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 39 |
End Page | 45 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 40012158 |
Web of Science KeyUT | 001440463800005 |
FullText URL | fulltext.pdf |
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Author | Ueda, Ayaka| Shinoda-Ito, Yuki| Takeuchi-Hatanaka, Kazu| Ito, Takashi| Ono, Shintaro| Hirai, Kimito| Omori, Kazuhiro| Yamamoto, Tadashi| Takashiba, Shogo| |
Keywords | Dental education Infection control Fluorescent dye Adenosine triphosphate Lactobacillus |
Published Date | 2025-02-08 |
Publication Title | BMC Oral Health |
Volume | volume25 |
Issue | issue1 |
Publisher | BMC |
Start Page | 199 |
ISSN | 1472-6831 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025. |
File Version | publisher |
PubMed ID | 39923078 |
DOI | 10.1186/s12903-025-05584-4 |
Web of Science KeyUT | 001416641300005 |
Related Url | isVersionOf https://doi.org/10.1186/s12903-025-05584-4 |
FullText URL | fulltext.pdf |
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Author | Ooba, Hikaru| Maki, Jota| Masuyama, Hisashi| |
Keywords | Perinatal mental disorders Voice analysis Machine learning Screening Pregnant women |
Published Date | 2025-02-08 |
Publication Title | Discover Mental Health |
Volume | volume5 |
Issue | issue1 |
Publisher | Springer Nature |
Start Page | 12 |
ISSN | 2731-4383 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025 |
File Version | publisher |
PubMed ID | 39920468 |
DOI | 10.1007/s44192-025-00138-0 |
Web of Science KeyUT | 001415532800001 |
Related Url | isVersionOf https://doi.org/10.1007/s44192-025-00138-0 |
FullText URL | fulltext.pdf |
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Author | Yagi, Tomohiko| Kagawa, Shunsuke| Nogi, Shohei| Taniguchi, Atsuki| Yoshimoto, Masashi| Suemori, Kanto| Nagai, Yasuo| Fujita, Shuto| Kuroda, Shinji| Kikuchi, Satoru| Kakiuchi, Yoshihiko| Teraishi, Fuminori| Takagi, Kosei| Ohara, Toshiaki| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
Keywords | Cancer-associated fibroblasts Neutrophil Anti-fibrotic agent Pirfenidone |
Published Date | 2025-02-04 |
Publication Title | Cancer Immunology, Immunotherapy |
Volume | volume74 |
Issue | issue3 |
Publisher | Springer |
Start Page | 96 |
ISSN | 0340-7004 |
NCID | AA00598499 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025 |
File Version | publisher |
PubMed ID | 39904796 |
DOI | 10.1007/s00262-025-03946-z |
Web of Science KeyUT | 001413348800005 |
Related Url | isVersionOf https://doi.org/10.1007/s00262-025-03946-z |
JaLCDOI | 10.18926/AMO/68356 |
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FullText URL | 79_1_031.pdf |
Author | Maeda, Shigeru| Pimkhaokham, Atiphan| Yoshida, Michihiro| Hosoi, Hiroki| Ohshima, Ayako| Kurisu, Ryoko| Utsumi, Nozomi| Higuchi, Hitoshi| Miyawaki, Takuya| |
Abstract | We retrospectively analyzed the safety of the use of articaine, an amide-type local anesthetic, in Japanese dental patients (n=300) treated in Thailand in 2015-2017. The dosage, adverse events (AEs) caused by local anesthesia, and treatment efficacy were examined. Articaine, which is safe for patients with liver impairments due to its unique metabolism, has not been thoroughly tested in Japan for doses above 5.1 mL. Eighty of the present patients had undergone root canal treatment (RCT), 71 underwent tooth extraction, and 149 underwent implant-related surgery. More than three articaine cartridges were used in 41 patients, and no AEs occurred in these cases. The only AE occurred in a 52-year-old woman who was treated with three cartridges and presented with what appeared to be hyperventilation syndrome; she later recovered and received her dental treatment as scheduled. Most treatments were completed with three or fewer cartridges, suggesting that this number is generally sufficient. Our findings, particularly the low AE risk even with doses exceeding three cartridges, support the potential applicability of the overseas recommended maximum dose of articaine (7 mg/kg) in Japanese patients. This conclusion is significant for advancing dental anesthetic practices and ensuring patient safety and treatment efficacy in Japan. |
Keywords | dental anesthesia local anesthesia drug-related side effect adverse reaction |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-02 |
Volume | volume79 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 31 |
End Page | 37 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 40012157 |
Web of Science KeyUT | 001440463800004 |
JaLCDOI | 10.18926/AMO/68355 |
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FullText URL | 79_1_021.pdf |
Author | Yamamoto, Yasuhiro| Haraguchi, Takafumi| Matsuda, Kaori| Okazaki, Yoshio| Kimoto, Shin| Tanji, Nozomu| Matsumoto, Atsushi| Kobayashi, Yasuyuki| Mimura, Hidefumi| Hiraki, Takao| |
Abstract | We developed a machine learning model for predicting prostate cancer (PCa) grades using radiomic features of magnetic resonance imaging. 112 patients diagnosed with PCa based on prostate biopsy between January 2014 and December 2021 were evaluated. Logistic regression was used to construct two prediction models, one using radiomic features and prostate-specific antigen (PSA) values (Radiomics model) and the other Prostate Imaging-Reporting and Data System (PI-RADS) scores and PSA values (PI-RADS model), to differentiate high-grade (Gleason score [GS] ≥ 8) from intermediate or low-grade (GS < 8) PCa. Five imaging features were selected for the Radiomics model using the Gini coefficient. Model performance was evaluated using AUC, sensitivity, and specificity. The models were compared by leave-one-out cross-validation with Ridge regularization. Furthermore, the Radiomics model was evaluated using the holdout method and represented by a nomogram. The AUC of the Radiomics and PI-RADS models differed significantly (0.799, 95% CI: 0.712-0.869; and 0.710, 95% CI: 0.617-0.792, respectively). Using holdout method, the Radiomics model yielded AUC of 0.778 (95% CI: 0.552-0.925), sensitivity of 0.769, and specificity of 0.778. It outperformed the PI-RADS model and could be useful in predicting PCa grades, potentially aiding in determining appropriate treatment approaches in PCa patients. |
Keywords | prostate cancer machine learning prostate Imaging-Reporting and Data System radiomics Gleason score |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-02 |
Volume | volume79 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 21 |
End Page | 30 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 40012156 |
Web of Science KeyUT | 001440463800003 |
JaLCDOI | 10.18926/AMO/68354 |
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FullText URL | 79_1_009.pdf |
Author | Ikeya, Nanami| Okita, Atsushi| Hashida, Shinsuke| Yamamoto, Sumiharu| Ikeda, Hirokuni| Tsukuda, Kazunori| Toyooka, Shinichi| |
Abstract | Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy. |
Keywords | sarcopenia skeletal muscle gastric cancer gastrectomy erector spinae muscle |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-02 |
Volume | volume79 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 9 |
End Page | 19 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 40012155 |
Web of Science KeyUT | 001440463800002 |
JaLCDOI | 10.18926/AMO/68353 |
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FullText URL | 79_1_001.pdf |
Author | Thiha, Moe| Hikita, Takao| Nakayama, Masanori| |
Abstract | Endothelial cell polarity is fundamental to the organization and function of blood vessels, influencing processes such as angiogenesis, vascular stability, and response to shear stress. This review elaborates on the molecular mechanisms that regulate endothelial cell polarity, focusing on key players like the PAR polarity complex and Rho family GTPases. These pathways coordinate the front–rear, apical–basal and planar polarity of endothelial cells, which are essential for the proper formation and maintenance of vascular structures. In health, endothelial polarity ensures not only the orderly development of blood vessels, with tip cells adopting distinct polarities during angiogenesis, but also ensures proper vascular integrity and function. In disease states, however, disruptions in polarity contribute to pathologies such as coronary artery disease, where altered planar polarity exacerbates atherosclerosis, and cancer, where disrupted polarity in tumor vasculature leads to abnormal vessel growth and function. Understanding cell polarity and its disruption is fundamental not only to comprehending how cells interact with their microenvironment and organize themselves into complex, organ-specific tissues but also to developing novel, targeted, and therapeutic strategies for a range of diseases, from cardiovascular disorders to malignancies, ultimately improving patient outcomes. |
Keywords | blood vessel endothelial cell cell polarity atherosclerosis cancer |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2025-02 |
Volume | volume79 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 1 |
End Page | 7 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 40012154 |
Web of Science KeyUT | 001440463800001 |
FullText URL | fulltext.pdf |
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Author | Kono, Reika| Hamasaki, Ichiro| Kishimoto, Fumiko| Shibata, Kiyo| Morisawa, Shin| Morizane, Yuki| |
Keywords | Orbital pulley Sagging eye syndrome Distance esotropia Cyclovertical strabismus Aging |
Note | The version of record of this article, first published in Japanese Journal of Ophthalmology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10384-024-01141-8| |
Published Date | 2025-02-04 |
Publication Title | Japanese Journal of Ophthalmology |
Volume | volume69 |
Issue | issue1 |
Publisher | Springer Science and Business Media LLC |
Start Page | 1 |
End Page | 9 |
ISSN | 0021-5155 |
NCID | AA00691177 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024 |
File Version | publisher |
PubMed ID | 39903417 |
DOI | 10.1007/s10384-024-01141-8 |
Web of Science KeyUT | 001412688900001 |
Related Url | isVersionOf https://doi.org/10.1007/s10384-024-01141-8 |
FullText URL | fulltext.pdf |
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Author | Mukunoki, Hiroshi| Okoshi, Hirofumi| |
Keywords | free trade agreements managerial incentives rules of origin transfer pricing |
Published Date | 2025-01-28 |
Publication Title | Review of International Economics |
Publisher | Wiley |
ISSN | 0965-7576 |
NCID | AA10959196 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
DOI | 10.1111/roie.12790 |
Web of Science KeyUT | 001406893100001 |
Related Url | isVersionOf https://doi.org/10.1111/roie.12790 |
FullText URL | fulltext20250213-02.pdf suppl20250213-02.pdf |
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Author | Mukohara, Fumiaki| Iwata, Kazuma| Ishino, Takamasa| Inozume, Takashi| Nagasaki, Joji| Ueda, Youki| Suzawa, Ken| Ueno, Toshihide| Ikeda, Hideki| Kawase, Katsushige| Saeki, Yuka| Kawashima, Shusuke| Yamashita, Kazuo| Kawahara, Yu| Nakamura, Yasuhiro| Honobe-Tabuchi, Akiko| Watanabe, Hiroko| Dansako, Hiromichi| Kawamura, Tatsuyoshi| Suzuki, Yutaka| Honda, Hiroaki| Mano, Hiroyuki| Toyooka, Shinichi| Kawazu, Masahito| Togashi, Yosuke| |
Keywords | cancer immunology somatic mutation T cell tumor-infiltrating lymphocytes |
Note | This is an Accepted Manuscript of an article published by Proceedings of the National Academy of Sciences.| This fulltext file will be available in Feb. 2025.| |
Published Date | 2024-08-21 |
Publication Title | Proceedings of the National Academy of Sciences |
Volume | volume121 |
Issue | issue35 |
Publisher | Proceedings of the National Academy of Sciences |
Start Page | e2320189121 |
ISSN | 0027-8424 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 the Author(s). |
File Version | author |
PubMed ID | 39167601 |
DOI | 10.1073/pnas.2320189121 |
Web of Science KeyUT | 001408603100001 |
Related Url | isVersionOf https://doi.org/10.1073/pnas.2320189121 |
Author | Arakawa, Jinta| Yabuki, Ryo| Uemori, Takeshi| Ito, Masato| Yaguchi, Kenichi| |
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Keywords | Small fatigue crack Crystal orientation CP-FEM EBSD |
Note | © 2025 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2027.| |
Published Date | 2025-03-15 |
Publication Title | Engineering Failure Analysis |
Volume | volume170 |
Publisher | Elsevier BV |
Start Page | 109242 |
ISSN | 1350-6307 |
NCID | AA11028313 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 Elsevier Ltd. |
File Version | author |
DOI | 10.1016/j.engfailanal.2024.109242 |
Web of Science KeyUT | 001405677600001 |
Related Url | isVersionOf https://doi.org/10.1016/j.engfailanal.2024.109242 |
FullText URL | fulltext.pdf |
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Author | Kobayashi, Yasuyuki| Sano, Shunji| Narumiya, Yuto| Kimura, Ayari| Suzuki, Etsuji| Kasahara, Shingo| Kotani, Yasuhiro| |
Keywords | Truncus arteriosus Staged repair Primary repair Pulmonary artery banding Risk stratification |
Note | The version of record of this article, first published in Pediatric Cardiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00246-025-03790-z| |
Published Date | 2025-01-30 |
Publication Title | Pediatric Cardiology |
Publisher | Springer Science and Business Media LLC |
ISSN | 0172-0643 |
NCID | AA00361536 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025 |
File Version | publisher |
PubMed ID | 39883183 |
DOI | 10.1007/s00246-025-03790-z |
Web of Science KeyUT | 001409350800001 |
Related Url | isVersionOf https://doi.org/10.1007/s00246-025-03790-z |
FullText URL | fulltext.pdf |
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Author | Matsumoto, Naomi| Mitsui, Takashi| Tamai, Kei| Hirota, Tomoya| Masuyama, Hisashi| Yorifuji, Takashi| |
Keywords | Cesarean delivery Delivery methods Long-term outcome Child development Outcome-wide approach |
Published Date | 2025-01-20 |
Publication Title | Scientific Reports |
Volume | volume15 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 2485 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025 |
File Version | publisher |
PubMed ID | 39833288 |
DOI | 10.1038/s41598-025-87043-2 |
Web of Science KeyUT | 001402008500024 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-025-87043-2 |
FullText URL | fulltext.pdf |
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Author | Morita, Satoru| Otsuka, Yuki| Masuda, Yohei| Soejima, Yoshiaki| Otsuka, Fumio| |
Keywords | calcium pyrophosphate crystal deposition disease crowned dens syndrome dental treatment fever neck pain |
Published Date | 2025-02-02 |
Publication Title | Clinical Case Reports |
Volume | volume13 |
Issue | issue2 |
Publisher | Wiley |
Start Page | e70168 |
ISSN | 2050-0904 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 39902195 |
DOI | 10.1002/ccr3.70168 |
Web of Science KeyUT | 001410822700001 |
Related Url | isVersionOf https://doi.org/10.1002/ccr3.70168 |
FullText URL | fulltext.pdf |
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Author | Yamada, Yuto| Fujiwara, Masaki| Nakaya, Naoki| Otsuki, Koji| Shimazu, Taichi| Fujimori, Maiko| Hinotsu, Shiro| Nagoshi, Kiwamu| Uchitomi, Yosuke| Inagaki, Masatoshi| |
Keywords | bipolar disorder cancer screening COVID-19 healthcare disparities schizophrenia |
Published Date | 2025-02-02 |
Publication Title | Psychiatry and Clinical Neurosciences Reports |
Volume | volume4 |
Issue | issue1 |
Publisher | Wiley |
Start Page | e70062 |
ISSN | 2769-2558 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 39902101 |
DOI | 10.1002/pcn5.70062 |
Web of Science KeyUT | 001410823100001 |
Related Url | isVersionOf https://doi.org/10.1002/pcn5.70062 |
FullText URL | fulltext.pdf |
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Author | Kato, Koji| Nakajima, Yoshiki| Xing, Jian| Kumazawa, Minoru| Ogawa, Haruya| Shen, Jian-Ren| Ifuku, Kentaro| Nagao, Ryo| |
Published Date | 2024-10-31 |
Publication Title | eLife |
Volume | volume13 |
Publisher | eLife Sciences Publications |
Start Page | RP99858 |
ISSN | 2050-084X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Kato, Nakajima, Xing et al. |
File Version | publisher |
PubMed ID | 39480899 |
DOI | 10.7554/eLife.99858 |
Web of Science KeyUT | 001394525300001 |
Related Url | isVersionOf https://doi.org/10.7554/eLife.99858 |
FullText URL | fulltext.pdf |
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Author | Matsumoto, Kazuyuki| Uchida, Daisuke| Takeuchi, Yasuto| Kato, Hironari| Fujii, Yuki| Harada, Kei| Hattori, Nao| Sato, Ryosuke| Obata, Taisuke| Matsumi, Akihiro| Miyamoto, Kazuya| Horiguchi, Shigeru| Tsutsumi, Koichiro| Yasui, Kazuya| Harada, Ryo| Fujii, Masakuni| Otsuka, Motoyuki| |
Keywords | ablation techniques endosonography neuroendocrine tumors pancreatic neoplasms pilot projects |
Published Date | 2025-01-29 |
Publication Title | DEN Open |
Volume | volume5 |
Issue | issue1 |
Publisher | Wiley |
Start Page | e70073 |
ISSN | 2692-4609 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 39885893 |
DOI | 10.1002/deo2.70073 |
Web of Science KeyUT | 001408662000001 |
Related Url | isVersionOf https://doi.org/10.1002/deo2.70073 |
Title Alternative | The List of Published by Members of the Faculty From January to December 2024. |
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FullText URL | srfa_114_027_038.pdf |
Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
Published Date | 2025-02-01 |
Volume | volume114 |
Start Page | 27 |
End Page | 38 |
ISSN | 2186-7755 |
language | Japanese |
File Version | publisher |
Title Alternative | Elucidation of plant-bacterial pathogen interactions for the control of bacterial blight on cruciferous crops |
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FullText URL | srfa_114_021_025.pdf |
Author | Sakata, Nanami| |
Abstract | Pseudomonas cannabina pv. alisalensis (Pcal), the causative agent of bacterial blight on cruciferous crops, is an economically important pathogen worldwide. We have conducted several studies on the interactions between plants and pathogenic bacteria to develop effective control strategies for this disease. Using forward and reverse genetics, we identified several virulence factors, including the type III secretion system, membrane transporters, transcriptional factors, and amino acid metabolism. Additionally, we emphasized the role of coronatine, a toxin produced by Pcal, which promotes stomatal reopening and suppresses salicylic acid accumulation in plants. We also examined plant defense mechanisms activated by one of the plant defense activators, acibenzolar-S-methyl (ASM). ASM enhanced stomatal-based defense, resulting in reduction of bacterial entry and disease development. Moreover, we explored innovative control strategies for bacterial disease and demonstrated that amino acids and cellulose nanofiber are efficient and environmentally friendly control strategies. These studies advance our understanding of plant-pathogen dynamics and offer promising, sustainable approaches for managing bacterial blight disease in cruciferous crops. |
Keywords | Plant pathogenic bacteria Pseudomonas Cruciferous Plant protection Stomata |
Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
Published Date | 2025-02-01 |
Volume | volume114 |
Start Page | 21 |
End Page | 25 |
ISSN | 2186-7755 |
language | Japanese |
File Version | publisher |