| ID | 15921 |
| Eprint ID | 15921
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| FullText URL | |
| Title Alternative | Studies on heparin in allergic reactions 1. Action of heparin on immediate hypersensitivity
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| Author |
Ono, Hatsuko
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| Abstract | The action of heparin on allergic reactions was examined in skin and bronchial reactions to chemical mediators, in the rat PCA reaction and antigen-induced degranulation of rat peritoneal mast cells. Heparin inhibited the histamine-induced skin reaction in rats. Bronchoconstriction caused by histamine and acetylcholine was also inhibited by pre-treatment with heparin. The skin reaction due to reaginic antibody (PCA), but not that due to precipitated antibody, in rats was inhibited by heparin administration. Heparin moderately inhibited the degranulation of rat peritoneal mast cells elicited by reaginic antibody, but the inhibitory action was not as strong as that of prednisolone or disodiumcromoglycate.
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| Keywords | heparin
reagin様抗体
皮内反応
化学伝達物質
肥満細胞
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| Published Date | 1987-06-30
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| Publication Title |
岡山医学会雑誌
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| Publication Title Alternative | Journal of Okayama Medical Association
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| Volume | volume99
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| Issue | issue5-6
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| Publisher | 岡山医学会
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| Publisher Alternative | Okayama Medical Association
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| Start Page | 537
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| End Page | 546
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| ISSN | 0030-1558
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| NCID | AN00032489
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| Content Type |
Journal Article
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| Official Url | https://www.jstage.jst.go.jp/article/joma1947/99/5-6/99_5-6_537/_article/-char/ja/
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| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
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| language |
Japanese
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| Copyright Holders | 岡山医学会
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| File Version | publisher
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| Refereed |
True
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| Eprints Journal Name | joma
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