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ID 47696
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Abstract
Anterior pituitary cells produce growth factors plus cytokines and their receptors. Although some of these pituitary growth factors and cytokines are known to be involved in the control of cell differentiation, proliferation and hormone production in the pituitary gland, their physiological roles remain unknown. Lots of evidence indicates that they are involved in the regulation of prolactin-secreting mammotroph cell proliferation. The regulation of mammotroph functions is a suitable system for understanding the intrapituitary regulatory system operated by growth factors and cytokines, since mammotrophs are the most actively proliferating cells in female pituitary glands. This review discusses the possible intrapituitary regulation of mammotroph differentiation and proliferation in rat and mouse pituitaries.
Keywords
pituitary
mammotroph
proliferation
rat
mouse
Published Date
2004-06
Publication Title
Zoological Science
Volume
volume21
Issue
issue6
Publisher
Zoological Society of Japan
Publisher Alternative
日本動物学会
Start Page
601
End Page
611
ISSN
0289-0003
NCID
AA10545874
Content Type
Journal Article
language
英語
Copyright Holders
© 2004 Zoological Society of Japan
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publisher
Refereed
True
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