Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype Presenting as Chorea During Treatment: A Case Report and Literature Review

Kitamura, Wataru; Ennishi, Daisuke; Yukawa, Ryoya; Sasaki, Ryo; Yoshida, Chikamasa; Takasuka, Hiroki; Fujiwara, Hideaki; Asada, Noboru; Nishimori, Hisakazu; Fujii, Keiko; Fujii, Nobuharu; Matsuoka, Ken-Ichi; Abe, Koji; Yoshino, Tadashi; Maeda, Yoshinobu

doi:10.2169/internalmedicine.7180-21

Permalink : http://escholarship.lib.okayama-u.ac.jp/62784

ID	62784
FullText URL	fulltext.pdf 2.56 MB
Author	Kitamura, Wataru Department of Hematology and Oncology, Okayama University Hospital Ennishi, Daisuke Center for Comprehensive Genomic Medicine, Okayama University Hospital Yukawa, Ryoya Department of Hematology and Oncology, Okayama University Hospital Sasaki, Ryo Department of Neurology, Okayama University Hospital Yoshida, Chikamasa Department of Hematology, Okayama City Hospital Takasuka, Hiroki Department of Hematology and Oncology, Okayama University Hospital Fujiwara, Hideaki Department of Hematology and Oncology, Okayama University Hospital Asada, Noboru Department of Hematology and Oncology, Okayama University Hospital Kaken ID researchmap Nishimori, Hisakazu Department of Hematology and Oncology, Okayama University Hospital Kaken ID researchmap Fujii, Keiko Division of Clinical Laboratory, Okayama University Hospital Fujii, Nobuharu Division of Blood Transfusion, Okayama University Hospital Kaken ID publons researchmap Matsuoka, Ken-Ichi Department of Hematology and Oncology, Okayama University Hospital Abe, Koji Department of Neurology, Okayama University Hospital Kaken ID publons researchmap Yoshino, Tadashi Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Kaken ID publons researchmap Maeda, Yoshinobu Department of Hematology and Oncology, Okayama University Hospital Kaken ID researchmap
Abstract	A 72-year-old man presented with chorea while undergoing treatment for recurrence of nodal peripheral T-cell lymphoma with T follicular helper (TFH) phenotype. An examination by brain N-isopropyl-p-iodoamphetamine (I-123-IMP)-single photon emission computed tomography (SPECT) revealed no abnormalities other than a decreased cerebral blood flow (CBF) in the left striatum. After four courses of salvage chemotherapy, his clinical symptoms and asymmetric cerebral perfusion improved, suggesting that the decreased CBF had caused chorea. The significance of brain SPECT has not been fully clarified in patients with chorea-associated malignant lymphoma, warranting further investigations. Brain SPECT is an alternative approach to identify abnormalities in such patients.
Keywords	peripheral T-cell lymphoma chorea single photon-emission computed tomography
Published Date	2021-10-01
Publication Title	Internal Medicine
Volume	volume60
Issue	issue19
Publisher	The Japanese Society of Internal Medicine
Start Page	3155
End Page	3160
ISSN	0918-2918
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	33814503
DOI	10.2169/internalmedicine.7180-21
Web of Science KeyUT	000706487700015
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.7180-21
License	https://creativecommons.org/licenses/by-nc-nd/4.0/
Citation	Wataru Kitamura, Daisuke Ennishi, Ryoya Yukawa, Ryo Sasaki, Chikamasa Yoshida, Hiroki Takasuka, Hideaki Fujiwara, Noboru Asada, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Ken-ichi Matsuoka, Koji Abe, Tadashi Yoshino, Yoshinobu Maeda, Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype Presenting as Chorea During Treatment: A Case Report and Literature Review, Internal Medicine, 2021, Volume 60, Issue 19, Pages 3155-3160