ID | 44361 |
FullText URL | |
Author |
Baba, Hiroki
Yamamoto, Hiroshi
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Abstract | A novel glycosyl donor, 4,6-di-O-acetyl-2,3-di-O-(4-methoxy-benzyl)-α-D-glucopyranosy bromide (15) was efficiently prepared from D-glucose in 8 steps. The first synthesis of 2’-O-(α-D-glucopyranosyl)biopterin (2) was achieved by treatment of the key precursor, N(2)-(N,N-dimethylamino- methylene)-1’-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (6) with 15 in the presence of silver triflate and tetramethylurea, followed by removal of the protecting groups.
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Keywords | Pterine Glycoside
Biopterin D-Glucoside
Pteridine
Selective α-Glycosylation
Protecting Group
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Published Date | 2009-02-01
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Publication Title |
Heterocycles
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Volume | volume77
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Issue | issue2
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Publisher | The Japan Institute of Heterocyclic Chemistry
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Start Page | 747
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End Page | 753
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ISSN | 1881-0942
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Content Type |
Journal Article
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Official Url | http://dx.doi.org/10.3987/COM-08-S(F)60
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language |
English
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Copyright Holders | © The Japan Institute of Heterocyclic Chemistry
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File Version | author
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Refereed |
True
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DOI | |
Web of Science KeyUT |