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ID 31004
JaLCDOI
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Author
Ichiyasu, Akira
Makino, Hirofumi
Abstract

Isolated rat glomerular basement membrane was treated with elastase and observed by transmission electron microscopy. The treatment with elastase revealed the fundamental structure of the glomerular basement membrane quite clearly, and enabled the observation of a sieve structure within the glomerular basement membrane. This sieve structure may play a major role in the filtration of blood as well as in the production of urine. Treatment with antibody showed that the sieve was mainly constituted of type IV collagen.

Keywords
glomerular basement membrane
enzymatic digestion
meshwork structure
type IV collagen
elastase
Amo Type
Article
Publication Title
Acta Medica Okayama
Published Date
1988-12
Volume
volume42
Issue
issue6
Publisher
Okayama University Medical School
Start Page
317
End Page
325
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT