ID | 66665 |
JaLCDOI | |
FullText URL | |
Author |
Akagi, Naoki
Department of Urology, Hyogo Medical University
Kanematsu, Akihiro
Department of Urology, Hyogo Medical University
Shigesaka, Koji
Department of Urology, Hyogo Medical University
Shimatani, Kimihiro
Department of Urology, Hyogo Medical University
Yamamoto, Shingo
Department of Urology, Hyogo Medical University
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Abstract | Bacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer frequently causes an intraprostatic BCG granuloma. We investigated the optimal timing for a prostate biopsy after BCG treatment by retrospectively analyzing the cases of 22 patients with non-muscle-invasive bladder cancer who underwent a prostate biopsy after BCG treatment at our institute (2013-2017). Biopsies were indicated for a rising prostate-specific antigen (PSA) level, positive digital rectal examination findings, or the appearance of de novo low apparent diffusion coefficient lesions on MRI. The control group was comprised of 28 age- and PSA-matched patients. The relationships among the cancer detection rate and the patients’ PSA levels and MRI findings were analyzed. Prostate cancer was detected by biopsy in only 13.9% (3/22) of the patients in the BCG group but in 78.5% (22/28) of the control patients (p=0.0001). The three patients in the BCG group in whom prostate cancer was detected had all undergone the biopsy > 1 year after their BCG treatment. The remaining biopsies were performed within 1 year after BCG treatment and resulted in no diagnoses of prostate cancer. We suggest that performing a prostate biopsy early after BCG treatment is not informative or useful.
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Keywords | bacillus Calmette-Guérin
prostate granuloma
prostate cancer
bladder cancer
prostate biopsy
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Amo Type | Original Article
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Publication Title |
Acta Medica Okayama
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Published Date | 2024-02
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Volume | volume78
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Issue | issue1
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Publisher | Okayama University Medical School
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Start Page | 9
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End Page | 13
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School
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File Version | publisher
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Refereed |
True
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PubMed ID |