Gastric Mucosa-associated Lymphoid Tissue Lymphoma That Relapsed after 11 Years Subsequent to Achieving Complete Remission

Inoo, Shoko; Iwamuro, Masaya; Tanaka, Takehiro; Kawahara, Yoshiro; Ootuka, Motoyuki

doi:10.2169/internalmedicine.2642-23

Permalink : https://ousar.lib.okayama-u.ac.jp/69186

ID	69186
FullText URL	fulltext.pdf 1.9 MB
Author	Inoo, Shoko Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Iwamuro, Masaya Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences ORCID Kaken ID publons researchmap Tanaka, Takehiro Department of Pathology, Okayama University Hospital ORCID Kaken ID publons Kawahara, Yoshiro Department of Practical Gastrointestinal Endoscopy, Okayama University Hospital Kaken ID researchmap Ootuka, Motoyuki Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
Abstract	A 38-year-old Japanese man was diagnosed with extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue in the stomach (gastric MALT lymphoma). Fluorescence in situ hybridization analysis revealed the absence of t (11;18) (q21;q21) translocation but the presence of extra copies of MALT1, indicating tetrasomy 18. Helicobacter pylori eradication led to complete remission (CR). However, the gastric MALT lymphoma relapsed after 11 years old. This case underscores the need for long-term observation (>10 years) of patients with gastric MALT lymphoma. Further investigation is warranted to elucidate the correlation between trisomy/tetrasomy 18 and the recurrence propensity.
Keywords	gastric MALT lymphoma H. pylori relapse
Published Date	2024-06-15
Publication Title	Internal Medicine
Volume	volume63
Issue	issue12
Publisher	Japanese Society of Internal Medicine
Start Page	1697
End Page	1702
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	37926540
DOI	10.2169/internalmedicine.2642-23
CRID	1390582008203472512
Web of Science KeyUT	001274076200004
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.2642-23
License	https://creativecommons.org/licenses/by-nc-nd/4.0/