Palladium-Catalyzed Regio- and Stereoselective Carbothiolation of Terminal Alkynes with Azolyl Sulfides

Iwasaki, Masayuki; Topolovčan, Nikola; Hu, Hao; Nishimura, Yugo; Gagnot, Glwadys; nakorn, Rungsaeng Na; Yuvacharaskul, Ramida; Nakajima, Kiyohiko; Nishihara, Yasushi

doi:10.1021/acs.orglett.6b00503

Permalink : http://escholarship.lib.okayama-u.ac.jp/55377

ID	55377
FullText URL	Org_Lett_18_7_1642.pdf 220 KB
Author	Iwasaki, Masayuki Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University ORCID Kaken ID publons researchmap Topolovčan, Nikola Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University Hu, Hao Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University Nishimura, Yugo Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University Gagnot, Glwadys Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University nakorn, Rungsaeng Na Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University Yuvacharaskul, Ramida Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University Nakajima, Kiyohiko Department of Chemistry, Aichi University of Education Nishihara, Yasushi Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology, Okayama University ORCID Kaken ID publons researchmap
Abstract	Palladium-catalyzed carbothiolation of terminal alkynes with azolyl sulfides affords various 2-(azolyl)alkenyl sulfides with perfect regio- and stereoselectivities. The present addition reaction proceeded through a direct cleavage of carbon-sulfur bonds in azolyl sulfides. The resulting adducts that are useful intermediates in organic synthesis are further transformed to multisubstituted olefins containing azolyl moieties.
Note	This is an Accepted Manuscript of an article published by American Chemical Society
Published Date	2016-03-21
Publication Title	Organic Letters
Volume	volume18
Issue	issue7
Publisher	American Chemical Society
Start Page	1642
End Page	1645
ISSN	1523-7060
NCID	AA11347843
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version	author
PubMed ID	26998829
DOI	10.1021/acs.orglett.6b00503
Web of Science KeyUT	000373519600037
Related Url	https://doi.org/10.1021/acs.orglett.6b00503