Rhenium-Catalyzed Cyclization via 1,2-Iodine and 1,5-Hydrogen Migration for the Synthesis of 2-Iodo-1H-indenes

ID	58546
FullText URL	Org_Lett_21_17_6756_6760.pdf 671 KB
Author	Murai, Masahito Graduate School of Natural Science and Technology, Okayama University ORCID Kaken ID publons researchmap Takai, Kazuhiko Graduate School of Natural Science and Technology, Okayama University ORCID Kaken ID publons researchmap
Abstract	A rhenium complex catalyzed the formation of 2-iodo-1H-indene derivatives through iodine and hydrogen migration of 3-iodopropargyl ethers. The reaction proceeded via generation of 1-iodoalkenylrhenium carbene species by sequential 1,2-iodine and 1,5-hydrogen shifts with readily available precursors under neutral conditions. The reaction mechanism and the reactivity of the generated alkenylcarbene species were also investigated.
Keywords	anti-markovnikov addition silyl enol ethers terminal alkynes metal vinylidenes cycloisomerization ruthenium complexes derivatives carbene functionalization
Published Date	2019-08-08
Publication Title	Organic Letters
Volume	volume21
Issue	issue17
Publisher	American Chemical Society
Start Page	6756
End Page	6760
ISSN	15237060
NCID	AA11347843
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	31393739
DOI	10.1021/acs.orglett.9b02380
Web of Science KeyUT	000485089300035
Related Url	isVersionOf https://doi.org/10.1021/acs.orglett.9b02380
Funder Name	Ministry of Education, Culture, Sports, Science and Technology
助成番号	18H03911 19H02719