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ID 65707
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Sugitate, Kazuma Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Yamashiro, Toshiki Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Takahashi, Ibuki Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-tobetsu, Hokkaido 0610293, Japan
Yamada, Koji Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido
Abe, Takumi Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University ORCID Kaken ID researchmap
Abstract
The previously reported structures of oxytrofalcatins B and C possess a benzoyl indole core. However, following synthesis and NMR comparison of both the proposed structure and the synthesized oxazole, we have revised the structure of oxytrofalcatins B and C as oxazoles. The synthetic route developed herein can further our understanding of the biosynthetic pathways that govern the production of natural 2,5-diaryloxazoles.
Note
This document is the unedited Author's version of a Submitted Work that was subsequently accepted for publication in The Journal of Organic Chemistry, copyright © 2023 American Chemical Society after peer review. To access the final edited and published work see https://doi.org/10.1021/acs.joc.3c00691.
This fulltext file will be available in Jul. 2024.
Published Date
2023-07-11
Publication Title
The Journal of Organic Chemistry
Volume
volume88
Issue
issue14
Publisher
American Chemical Society (ACS)
Start Page
9920
End Page
9926
ISSN
0022-3263
NCID
AA00704100
Content Type
Journal Article
language
English
OAI-PMH Set
岡山大学
Copyright Holders
© 2023 American Chemical Society
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DOI
Web of Science KeyUT
Related Url
isVersionOf https://doi.org/10.1021/acs.joc.3c00691
Funder Name
Japan Society for the Promotion of Science
Japan Science and Technology Agency
助成番号
22K06503
JPMJSP2126