| ID | 48397 |
| FullText URL | |
| Title Alternative | Usefulness of ICR mice as genetic resources
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| Author |
Yamamoto, Yoshie
Uchio-Yamada, Kozue
Takano, Kaoru
Ogura, Atsuo
Asano, Toshihiko
Nakagawa, Masarou
|
| Abstract | ICR(Yok:ICR)mice were introduced into the National Instltute of Infectious Diseases in 1965,and have been bred and produced there.Two inbred mutant mouse strains,MPS and ICGN,were created using(originated from)Yok:ICR mice in 1986.The MPS and ICGN mouse strains have served as the
animal disease models of mycoplasma infectious disease and congenital nephritic syndrome,respectively.
Genetic variations were detected by the genetic monitoring of Yok:ICR mice using biochemical markers.However, no difference was detected in gene expression profiles between the MPS and ICGN mouse strains.ICR mice may harbor genes that are spontaneously mutated,thereby allowing the creation of
new pathological models through the segregation and/or selection(screening)of mutant genes.
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| Note | 寄稿 (Contributions)
|
| Published Date | 2012-04
|
| Publication Title |
岡山実験動物研究会報
|
| Publication Title Alternative | Proceedings of Okayama Association for Laboratory Animal Science
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| Volume | volume28
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| Publisher | 岡山実験動物研究会
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| Publisher Alternative | Okayama Association for Laboratory Animal Science
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| Start Page | 59
|
| End Page | 62
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| Content Type |
Journal Article
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| language |
Japanese
|
| File Version | publisher
|
| Refereed |
False
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| Eprints Journal Name | poalas
|
