| ID | 13822 |
| Eprint ID | 13822
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| FullText URL | |
| Title Alternative | Studies on alveolar lymphocyte proliferation induced by Propionibacterium acnes in sarcoidosis Part 1. Specificity of alveolar lymphocyte response to Propionibacterium acnes in sarcoidosis
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| Author |
Maeta, Tsuyoshi
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| Abstract | The fact that alveolar lymphocytes in patients with active sarcoidosis are sensitized by Propionibacterium acnes (P. acnes) was previously reported by our group. Therefore, the responses of alveolar lymphocytes induced by Nocardia rubra and Streptococcus pyogenes were investigated and compared to those of P. acnes. The mean response rate of alveolar lymphocytes to P. acnes was significantly enhanced (1.89±1.45) in 12 untreated sarcoidosis patients compared with the response rates to Nocardia rubra (0.87±0.47) and Streptococcus pyogenes (0.64±0.30). Peripheral lymphocytes did not respond to any cell wall components of these organisms. Our findings indicate that alveolar lymphocytes in sarcoidosis are specifically sensitized by P. acnes, and suggest that P.acnes plays an important role in the induction of alveolar lymphocytes in sarcoidosis.
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| Keywords | sarcoidosis
alveolar lymphocyte
blastogenesis
P. acnes
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| Note | 原著
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| Published Date | 1993-08
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| Publication Title |
岡山医学会雑誌
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| Publication Title Alternative | Journal of Okayama Medical Association
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| Volume | volume105
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| Issue | issue7-8
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| Publisher | 岡山医学会
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| Publisher Alternative | Okayama Medical Association
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| Start Page | 657
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| End Page | 663
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| ISSN | 0030-1558
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| NCID | AN00032489
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| Content Type |
Journal Article
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| Official Url | https://www.jstage.jst.go.jp/article/joma1947/105/7-8/105_7-8_657/_article/-char/ja/
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| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
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| language |
Japanese
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| Copyright Holders | 岡山医学会
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| File Version | publisher
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| Refereed |
True
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| Eprints Journal Name | joma
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