ID | 56681 |
FullText URL | |
Author |
Elgaml, Abdelaziz
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Miyoshi, Shin-ichi
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Abstract | Vibrio vulnificus is a halophilic estuarine bacterium, but this species causes fatal septicemia in humans. V. vulnificus may encounter many kinds of stresses either in the natural environment or in the human body. One of the striking stresses is the exposure to the reactive oxygen species including nitric oxide (NO). The present study revealed that NO could participate in the regulation of the V. vulnificus community behavior. When the bacterium was cultivated in the presence of sub-lethal doses of an NO donor, the expression of the genes encoding NO-detoxifying enzymes was significantly increased. The NO donor was also found to cause significant increase in production of a metalloprotease, a putative virulence factor, by the bacterium.
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Keywords | Vibrio vulnificus
Nitric oxide
Oxidative stress
Detoxification
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Note | Note
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Published Date | 2015
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Publication Title |
Biocontrol Science
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Volume | volume20
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Issue | issue3
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Publisher | The Society for Antibacterial and Antifungal Agents
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Start Page | 199
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End Page | 203
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ISSN | 13424815
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NCID | AA11169621
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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File Version | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
Related Url | isVersionOf https://doi.org/10.4265/bio.20.199
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Project |
Collaborative Research of Okayama University for Infectious Diseases in India
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