FullText URL fulltext.pdf
Author Imoto, Ryoji| Otani, Yoshihiro| Fujii, Kentaro| Ishida, Joji| Hirano, Shuichiro| Kemmotsu, Naoya| Suruga, Yasuki| Mizuta, Ryo| Kegoya, Yasuhito| Inoue, Yohei| Umeda, Tsuyoshi| Hokama, Madoka| Washio, Kana| Yanai, Hiroyuki| Tanaka, Shota| Satomi, Kaishi| Ichimura, Koichi| Date, Isao|
Keywords Tectal glioma Lower grade glioma KRAS H3 K27M Molecular analysis
Note The version of record of this article, first published in Brain Tumor Pathology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10014-024-00494-9|
Published Date 2024-10-21
Publication Title Brain Tumor Pathology
Publisher Springer Science and Business Media LLC
ISSN 1433-7398
NCID AA11203151
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39432011
DOI 10.1007/s10014-024-00494-9
Web of Science KeyUT 001339711100001
Related Url isVersionOf https://doi.org/10.1007/s10014-024-00494-9
FullText URL fulltext.pdf
Author Fujiwara, Tomohiro| Kunisada, Toshiyuki| Nakata, Eiji| Nishida, Kenji| Yanai, Hiroyuki| Nakamura, Tomoki| Tanaka, Kazuhiro| Ozaki, Toshifumi|
Keywords alveolar soft part sarcoma surgery chemotherapy targeted therapy immunotherapy
Published Date 2023-08-25
Publication Title Japanese Journal of Clinical Oncology
Volume volume53
Issue issue11
Publisher Oxford University Press (OUP)
Start Page 1009
End Page 1018
ISSN 1465-3621
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37626447
DOI 10.1093/jjco/hyad102
Web of Science KeyUT 001080372000001
Related Url isVersionOf https://doi.org/10.1093/jjco/hyad102
JaLCDOI 10.18926/AMO/66676
FullText URL 78_1_089.pdf
Author Toshima, Kei| Shien, Tadahiko| Nishimura, Midori Filiz| Suzuki, Yoko| Nakamoto, Shogo| Uno, Maya| Yoshioka, Ryo| Tsukioki, Takahiro| Takahashi, Yuko| Iwamoto, Takayuki| Iwatani, Tsuguo| Yanai, Hiroyuki|
Abstract We report our experience with the diagnosis and treatment of an ectopic breast cancer arising within an axillary lymph node. The patient was a 65-year-old woman diagnosed breast cancer and axillary lymph node metastasis. We performed a partial mastectomy and axillary lymph node dissection. Postoperative pathology revealed no malignant lesions in the breast; however, a nodule in one of axillary lymph nodes had mixed benign and malignant components, leading to a diagnosis of invasive ductal carcinoma derived from ectopic mammary tissue. This case represents a very rare form of breast cancer, and the malignancy was difficult to distinguish from metastasis.
Keywords breast cancer ectopic breast cancer axillary lymph node
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-02
Volume volume78
Issue issue1
Publisher Okayama University Medical School
Start Page 89
End Page 93
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38419320
Web of Science KeyUT 001204421300001
JaLCDOI 10.18926/AMO/65502
FullText URL 77_3_323.pdf
Author Makino, Keigo| Otani, Yoshihiro| Fujii, Kentaro| Ishida, Joji| Hirano, Shuichiro | Suruga, Yasuki| Washio, Kana| Nishida, Kenji| Yanai, Hiroyuki| Tomida, Shuta| Ennishi, Daisuke| Date, Isao|
Abstract In the current World Health Organization classification of central nervous system tumors, comprehensive genetic and epigenetic analyses are considered essential for precise diagnosis. A 14-year-old male patient who presented with a cerebellar tumor was initially diagnosed with glioblastoma and treated with radiation and concomitant temozolomide chemotherapy after resection. During maintenance temozolomide therapy, a new contrast-enhanced lesion developed in the bottom of the cavity formed by the resection. A second surgery was performed, but the histological findings in specimens from the second surgery were different from those of the first surgery. Although genome-wide DNA methylation profiling was conducted using frozen tissue for a precise diagnosis, the proportion of tumor cells was insufficient and only normal cerebellum was observed. We then performed comprehensive genetic analysis using formalin-fixed paraffin-embedded sections, which revealed MYCN amplification without alteration of IDH1, IDH2, or Histone H3. Finally, the patient was diagnosed with pediatric-type diffuse high-grade glioma, H3-wildtype and IDH-wildtype. In conclusion, comprehensive genetic and epigenetic analysis should be considered in pediatric brain tumor cases.
Keywords comprehensive genomic profiling pediatric brain tumor genome-wide DNA methylation MYCN
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-06
Volume volume77
Issue issue3
Publisher Okayama University Medical School
Start Page 323
End Page 330
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37357634
Web of Science KeyUT 001025850000001
FullText URL fulltext.pdf
Author Fujiwara, Tomohiro| Yanai, Hiroyuki| Hagiya, Hideharu|
Keywords manubrium sternal infection tuberculosis
Published Date 2023-05-01
Publication Title Clinical Case Reports
Volume volume11
Issue issue5
Publisher Wiley
Start Page e7119
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37143459
DOI 10.1002/ccr3.7119
Web of Science KeyUT 000978608200001
Related Url isVersionOf https://doi.org/10.1002/ccr3.7119
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Abe, Makoto| Sakae, Hiroyuki| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Tanaka, Takehiro| Kawano, Seiji| Otsuka, Fumio| Kawahara, Yoshiro| Yanai, Hiroyuki| Okada, Hiroyuki|
Keywords eradication flow cytometry Helicobacter pylori T lymphocytes
Published Date 2022-08-26
Publication Title Medicine
Volume volume101
Issue issue34
Publisher Lippincott Williams & Wilkins
Start Page e30241
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 36042652
DOI 10.1097/MD.0000000000030241
Web of Science KeyUT 000847532100050
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000030241
FullText URL fulltext.pdf
Author Egusa, Yuria| Nishimura, Midori Filiz| Baba, Satoko| Takeuchi, Kengo| Makino, Takuma| Tachibana, Tomoyasu| Nishikori, Asami| Fujita, Azusa| Yanai, Hiroyuki| Sato, Yasuharu|
Keywords secretory carcinoma salivary gland mammary analogue secretory carcinoma Giemsa staining cytopathology fine-needle aspiration ETV6-NTRK3 fusion
Published Date 2021-12-07
Publication Title Diagnostics
Volume volume11
Issue issue12
Publisher MDPI
Start Page 2284
ISSN 2075-4418
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34943521
DOI 10.3390/diagnostics11122284
Web of Science KeyUT 000737113900001
Related Url isVersionOf https://doi.org/10.3390/diagnostics11122284
FullText URL fulltext.pdf
Author Futagawa, Mashu| Yamamoto, Hideki| Kochi, Mariko| Urakawa, Yusaku| Sogawa, Reimi| Kato, Fumino| Okazawa-Sakai, Mika| Ennishi, Daisuke| Shinozaki, Katsunori| Inoue, Hirofumi| Yanai, Hiroyuki| Hirasawa, Akira|
Keywords RAD51D Splice variant Leiomyosarcoma Homologous recombination (HR) Cancer susceptibility Presumed germline pathogenic variant (PGPV)
Published Date 2021-11-27
Publication Title Hereditary Cancer In Clinical Practice
Volume volume19
Issue issue1
Publisher BMC
Start Page 48
ISSN 1731-2302
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s).
File Version publisher
PubMed ID 34838098
DOI 10.1186/s13053-021-00205-x
Web of Science KeyUT 000722986000001
Related Url isVersionOf https://doi.org/10.1186/s13053-021-00205-x
FullText URL fulltext.pdf
Author Ono, Sawako| Marunaka, Hidenori| Yanai, Hiroyuki| Kawai, Hotaka| Takabatake, Kiyofumi| Nishida, Kenji| Toji, Tomohiro| Nakano, Keisuke| Nagatsuka, Hitoshi| Yoshino, Tadashi|
Keywords Lymphoepithelial carcinoma oral cavity lateral tongue
Published Date 2021-08-12
Publication Title reports
Volume volume4
Issue issue3
Publisher MDPI
Start Page 24
ISSN 2571-841X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
DOI 10.3390/reports4030024
Web of Science KeyUT 000701728000001
Related Url isVersionOf https://doi.org/10.3390/reports4030024
FullText URL fulltext.pdf
Author Ono, Sawako| Makino, Takuma| Yanai, Hiroyuki| Kawai, Hotaka| Takabatake, Kiyofumi| Nakano, Keisuke| Nishida, Kenji| Taniguchi, Kohei| Toji, Tomohiro| Nagatsuka, Hitoshi| Yoshino, Tadashi|
Keywords spindle cell carcinoma oral mucosa tongue
Published Date 2021-02-22
Publication Title reports
Volume volume4
Issue issue1
Publisher MDPI
Start Page 5
ISSN 2571-841X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
DOI 10.3390/reports4010005
Web of Science KeyUT 000681709500001
Related Url isVersionOf https://doi.org/10.3390/reports4010005
FullText URL fulltext.pdf
Author Obayashi, Yuka| Kawano, Seiji| Sakae, Hiroyuki| Abe, Makoto| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Iwamuro, Masaya| Kawahara, Yoshiro| Tanaka, Takehiro| Yanai, Hiroyuki| Okada, Hiroyuki|
Keywords background gastric mucosa gastric cancer inflammation Helicobacter pylori propensity score matching
Published Date 2021-04-01
Publication Title Internal Medicine
Volume volume60
Issue issue7
Publisher Japanese Society of Internal Medicine
Start Page 969
End Page 976
ISSN 0918-2918
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 33162475
NAID 130008014372
DOI 10.2169/internalmedicine.5486-20
Web of Science KeyUT 000637009100001
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.5486-20
FullText URL fulltext.pdf
Author Inoue, Hirofumi| Tomida, Shuta| Horiguchi, Shigeru| Kato, Hironari| Matsuoka, Hiromi| Sanehira, Etsuko| Matsuoka, Masashi| Yanai, Hiroyuki| Hirasawa, Akira| Toyooka, Shinichi|
Keywords cancer genomic profiling tests formalin‐fixed paraffin‐embedded (FFPE) tumor tissue genomic DNA extraction
Note This is the peer reviewed version of the following article: Hirofumi Inoue et. al. Best practices for the extraction of genomic DNA from formalin‐fixed paraffin‐embedded tumor tissue for cancer genomic profiling tests. Pathology International (2021), which has been published in final form at https://doi.org/10.1111/pin.13086. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
This fulltext is available in March 2022.|
Published Date 2021-03-03
Publication Title Pathology International
Volume volume71
Publisher Wiley
Start Page 360
End Page 364
ISSN 1320-5463
NCID AA10984364
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 33657250
DOI 10.1111/pin.13086
Web of Science KeyUT 000624843200001
Related Url isVersionOf https://doi.org/10.1111/pin.13086
FullText URL JOS_24_2_377.pdf
Author Omori, Toshinori| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Takeda, Ken| Hasei, Joe| Yoshida, Aki| Yanai, Hiroyuki| Ozaki, Toshifumi|
Published Date 2019-03
Publication Title Journal of Orthopaedic Science
Volume volume24
Issue issue2
Publisher Elsevier
Start Page 377
End Page 381
ISSN 0949-2658
NCID AA11627828
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2016 The Japanese Orthopaedic Association
File Version author
PubMed ID 28187993
DOI 10.1016/j.jos.2016.12.011
Web of Science KeyUT 000460662100033
Related Url isVersionOf https://doi.org/10.1016/j.jos.2016.12.011
Author Okada, Yoshiki| Abe, Nobuhiro| Hisamori, Noriyuki| Kaneeda, Toshiaki| Moriyama, Shigeaki| Ohmori, Hitoshi| Mizutani, Masayoshi| Yanai, Hiroyuki| Nakashima, Yoshio| Yokoyama, Yusuke| Ozaki, Toshifumi|
Published Date 2017-02
Publication Title Acta Medica Okayama
Volume volume71
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/AMO/54825
JaLCDOI 10.18926/AMO/54505
FullText URL 70_4_285.pdf
Author Tanaka, Takashi| Gobara, Hideo| Inai, Ryota| Iguchi, Toshihiro| Tada, Akihiro| Sato, Shuhei| Yanai, Hiroyuki| Kanazawa, Susumu|
Abstract We present a case of a 66-year-old man with esophageal carcinoma. 18Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for evaluating distant metastasis and staging revealed 18F-FDG uptake in the third lumbar vertebra and other vertebrae. Magnetic resonance imaging could not differentiate bone metastases from benign bone lesions. We considered the possibility of bone marrow reconversion. 111Indium chloride (111In-Cl3) scintigraphy with single-photon emission computed tomography/computed tomography (SPECT/CT) revealed erythroid bone marrow components in the bone lesions. The diagnosis of bone marrow reconversion was pathologically confirmed by a bone biopsy of the third lumbar vertebra. The patient underwent esophagectomy and has remained disease-free in the 2 years since. To the best of our knowledge, this is the first report to describe the usefulness of 111In-Cl3 with SPECT/CT for the diagnosis of bone marrow reconversion.
Keywords 111Indium chloride scintigraphy SPECT/CT bone marrow reconversion 18F-FDG PET/CT bone metastasis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2016-08
Volume volume70
Issue issue4
Publisher Okayama University Medical School
Start Page 285
End Page 289
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 27549674
Web of Science KeyUT 000384748600009
JaLCDOI 10.18926/AMO/54423
FullText URL 70_3_223.pdf
Author Ebara, Shin| Kobayashi, Yasuyuki| Sasaki, Katsumi| Araki, Motoo| Sugimoto, Morito| Wada, Koichirou| Fujio, Kei| Takamoto, Atsushi| Watanabe, Toyohiko| Yanai, Hiroyuki| Nasu, Yasutomo|
Abstract The present case report describes a case of recurrent and advanced urachal carcinoma including neuroendocrine features with iliac bone metastasis after partial cystectomy and adjuvant chemotherapy consisting of irinotecan and cisplatin in a 32-year-old man. He received gemcitabine/cisplatin/ paclitaxel (GCP) combination chemotherapy, consisting of gemcitabin (1,000mg/m2) on day 1, 8, cisplatin (70mg/m2) on day 1, and paclitaxel (80mg/m2) on day 1 and 8. After three cycles of chemotherapy, PET-CT showed complete regression of the disease. So the patient underwent total cystourethrectomy, and histological examination showed an almost complete pathological response. External beam radiation therapy was also given to the ileac bone metastasis regions. However, PET-CT taken 17 months after the external beam radiation showed multiple lung metastases. He received GCP chemotherapy again, which resulted in a complete response again after three cycles of chemotherapy. This is the first report on GCP chemotherapy used not only as a salvage chemotherapy but also as a rechallenge regimen for metastatic urachal cancer including a neuroendocrine component.
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2016-06
Volume volume70
Issue issue3
Publisher Okayama University Medical School
Start Page 223
End Page 227
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 27339213
Web of Science KeyUT 000379406100011
JaLCDOI 10.18926/AMO/53341
FullText URL 69_2_119.pdf
Author Terasaka, Tomohiro| Hagiya, Hideharu| Kimura, Kosuke| Nada, Takahiro| Nakamura, Eri| Hanayama, Yoshihisa| Sugiyama, Hitoshi| Kobayashi, Yasuyuki| Yanai, Hiroyuki| Otsuka, Fumio|
Abstract We report the case of a 46-year-old hypertensive Japanese female with renal insufficiency related to unilateral renal hypoplasia. The patient was found to have developed paraganglioma in the retroperitoneal space over a 5-year period. Catecholamine-producing tumors are not usually recognized as conditions associated with renal hypoplasia. Our long-term observation of the patient eventually led us to the diagnosis of paraganglioma. In hypertensive patients with chronic kidney disease, not only the renin-angiotensin-aldosterone system but also catecholamine activity may be involved, particularly in the patients whose cases are complicated with unilateral renal hypoplasia.
Keywords catecholamine paraganglioma renal hypoplasia renovascular hypertension secondary hypertension
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2015-04
Volume volume69
Issue issue2
Publisher Okayama University Medical School
Start Page 119
End Page 122
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25899634
Web of Science KeyUT 000353181700007
Author Yanai, Hiroyuki|
Published Date 2013-08-01
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue2
Content Type Journal Article
Author Tanabe, Shunsuke| Shirakawa, Yasuhiro| Maeda, Naoaki| Ohara, Toshiaki| Noma, Kazuhiro| Sakurama, Kazufumi| Yanai, Hiroyuki| Yamatsuji, Tomoki| Naomoto, Yoshio| Fujiwara, Toshiyoshi|
Published Date 2012-08-01
Publication Title 岡山医学会雑誌
Volume volume124
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/AMO/45273
FullText URL 65_2_135.pdf
Author Matsuo, Toshihiko| Himei, Kengo| Ishii, Keita| Ichimura, Kouichi| Yanai, Hiroyuki| Nose, Soichiro| Mimura, Tetsushige|
Abstract An 18-year-old woman with a 2-year history of hypertension and headache was diagnosed with noradrenalin-secreting bilateral adrenal pheochromocytomas with paragangliomas in the background of von Hippel-Lindau disease with family histories and a missense mutation, 712C to T (Arg167Trp) in the VHL gene. She had optic disc hemangioma in the left eye which gradually enlarged and caused serous retinal detachment on the macula in one year. Low-dose external beam radiation (20 Gy) was administered to the left eye using a lens-sparing single lateral technique. She underwent craniotomy for cerebellar hemangioblastoma at the age of 22 years and total pancreatectomy for multiple neuroendocrine tumors at the age of 24 years. In the 6-year follow-up period after the radiotherapy, the optic disc hemangioma gradually reduced in size and its activity remained low, allowing good central vision to be maintained. External beam radiation is recommended as a treatment option for the initial therapy for optic disc hemangioma.
Keywords retinal (papillary, optic disc) hemangioma von Hippel-Lindau disease pheochromocytoma pancreatic neuroendocrine tumor external beam radiation (radiotherapy)
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 135
End Page 141
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519372
Web of Science KeyUT 000289818800010