| ID | 61442 |
| JaLCDOI | |
| FullText URL | |
| Author |
Minato, Keitaro
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences
Hirano, Toru
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences
Kawashima, Hiroyuki
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences
Yamagishi, Tetsuro
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences
Watanabe, Keigo
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences
Kaken ID
publons
researchmap
Ohashi, Masayuki
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences
Ogose, Akira
Department of Orthopedic Surgery, Uonuma Kikan Hospital
Endo, Naoto
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences
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| Abstract | A 21-year-old man consulted our hospital for treatment of a spinal giant cell tumor (GCT) of Enneking stage III. Lower lumbar-spine tumors and severe spinal canal stenosis are associated with high risk for surgical mor-bidity. Stability was temporarily secured with a percutaneous pedicle screw fixation in combination with deno-sumab, which shrank the tumor. Total en bloc spondylectomy was then performed 6 months after initiation of denosumab, and the patient was followed for 3 years. There was no local recurrence, and bony fusion was obtained. Minimally invasive surgery and denosumab allowed safer and easier treatment of a collapsing lower lumbar extra-compartmental GCT.
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| Keywords | spinal stabilization
denosumab
spondylectomy
giant cell tumor
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| Amo Type | Case Report
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| Publication Title |
Acta Medica Okayama
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| Published Date | 2021-02
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| Volume | volume75
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| Issue | issue1
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| Publisher | Okayama University Medical School
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| Start Page | 95
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| End Page | 101
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| ISSN | 0386-300X
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| NCID | AA00508441
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| Content Type |
Journal Article
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| language |
English
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| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School
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| File Version | publisher
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| Refereed |
True
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| PubMed ID |
