FullText URL | fulltext.pdf |
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Author | Hayashi, Keigo| Sada, Ken-Ei| Asano, Yosuke| Hiramatsu Asano, Sumie| Yamamura, Yuriko| Ohashi, Keiji| Morishita, Michiko| Watanabe, Haruki| Narazaki, Mariko| Matsumoto, Yoshinori| Wada, Jun| |
Keywords | Nephrology Rheumatology |
Published Date | 2020-10-30 |
Publication Title | Scientific Reports |
Volume | volume10 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 18715 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | 英語 |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2020 |
File Version | publisher |
PubMed ID | 33127957 |
DOI | 10.1038/s41598-020-75655-9 |
Web of Science KeyUT | 000591916900014 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-020-75655-9 |
FullText URL | fulltext.pdf |
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Author | Katsuyama, Eri| Miyawaki, Yoshia| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Hiramatsu-Asano, Sumie| Morishita, Michiko| Ohashi, Keiji| Watanabe, Haruki| Katsuyama, Takayuki| Narazaki, Mariko| Matsumoto, Yoshinori| Wada, Jun| |
Keywords | Lupus nephritis Active lesions Chronic lesions Urinary protein Serum creatinine |
Published Date | 2020-06-01 |
Publication Title | BMC Nephrology |
Volume | volume21 |
Issue | issue1 |
Publisher | BMC |
Start Page | 208 |
ISSN | 1471-2369 |
Content Type | Journal Article |
language | 英語 |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2020 |
File Version | publisher |
PubMed ID | 32487161 |
DOI | 10.1186/s12882-020-01868-9 |
Web of Science KeyUT | 000538054600002 |
Related Url | isVersionOf https://doi.org/10.1186/s12882-020-01868-9 |
JaLCDOI | 10.18926/AMO/59949 |
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FullText URL | 74_3_191.pdf |
Author | Ohashi, Keiji| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Asano, Sumie Hiramatsu| Miyawaki, Yoshia| Morishita, Michiko| Katsuyama, Eri| Watanabe, Haruki| Tatebe, Noriko| Narazaki, Mariko| Matsumoto, Yoshinori| Sunahori-Watanabe, Katsue| Kawabata, Tomoko| Yajima, Nobuyuki| Wada, Jun| |
Abstract | Chronic damage accumulation affects not only mortality but also quality of life in patients with systemic lupus erythematosus (SLE). Risk factors for chronic damage were explored in SLE through different onset eras. Two hundred forty-five patients at Okayama University Hospital and Showa University Hospital were divided into three groups based on the onset era: a past-onset group (onset before 1995; n=83), middle-onset group (1996-2009; n=88), and recent-onset group (after 2010; n=74). The mean Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) score as an index of chronic damage was 1.93, 1.24, and 0.53 in the past-, middle-, and recent-onset groups, respectively. In the pastonset group, the total SDI score was significantly associated with glucocorticoid monotherapy by linear regression analysis (β-coefficient [β]=0.63; 95% confidence interval [CI], 0.21-1.05) and C-reactive protein levels (β=0.67; 95% CI, 0.27-1.07). In the middle-onset group, the total SDI score was significantly associated with the SLE Disease Activity Index at registration (β=0.09; 95% CI, 0.03-0.12). Reducing the accumulation of chronic damage in SLE patients might be possible with the concomitant use of immunosuppressants and tight control of disease activity. |
Keywords | systemic lupus erythematosus chronic damage glucocorticoids, disease activity disease duration |
Amo Type | Original Article |
Published Date | 2020-06 |
Publication Title | Acta Medica Okayama |
Volume | volume74 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 191 |
End Page | 198 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | 英語 |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32577016 |
Web of Science KeyUT | 000543363400002 |
NAID | 120006862791 |
FullText URL | JCR25_4_45.pdf Fig.pdf |
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Author | Motokura, Yumi| Watanabe, Haruki| Yamamura, Yuriko| Kano, Yuzuki| Matsumoto, Yoshinori| Kawabata, Tomoko| Sada, Ken-ei| Wada, Jun| |
Published Date | 2019-06 |
Publication Title | Journal of Clinical Rheumatology |
Volume | volume25 |
Issue | issue4 |
Publisher | Lippincott, Williams & Wilkins |
Start Page | 45 |
End Page | 47 |
ISSN | 1076-1608 |
NCID | AA11016642 |
Content Type | Journal Article |
language | 英語 |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 29470260 |
DOI | 10.1097/RHU.0000000000000723 |
Web of Science KeyUT | 000470908400007 |
Related Url | isVersionOf https://doi.org/10.1097/RHU.0000000000000723 |
FullText URL | SR9_1_3054.pdf |
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Author | Hiramatsu, Sumie| Watanabe, Katsue S.| Zeggar, Sonia| Asano, Yosuke| Miyawaki, Yoshia| Yamamura, Yuriko| Katsuyama, Eri| Katsuyama, Takayuki| Watanabe, Haruki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Kawabata, Tomoko| Sada, Ken-Ei| Wada, Jun| |
Published Date | 2019-2-28 |
Publication Title | Scientific Reports |
Volume | volume9 |
Publisher | Nature Publishing Group |
Start Page | 3054 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | 英語 |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2019 |
File Version | Publisher |
PubMed ID | 30816218 |
DOI | 10.1038/s41598-019-38809-y |
Web of Science KeyUT | 000459891700064 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-019-38809-y |