Susceptibility of Rous sarcoma virus-specific sequences integrated into SR-C3H/He mouse ascites sarcoma cell chromatin to DNase I and DNase II.

Tstsui, Kimiko; Tsutsui, Ken; Oda, Takuzo

ID	32389
JaLCDOI	10.18926/AMO/32389
FullText URL	fulltext.pdf 714 KB
Author	Tstsui, Kimiko Tsutsui, Ken Kaken ID publons researchmap Oda, Takuzo
Abstract	The susceptibility of Rous sarcoma virus (RSV) genomes integrated in mouse ascites sarcoma cells (SR-C3H/He cells) to DNase I and DNase II was investigated. Approximately half of the viral sequences were sensitive to DNase I and DNase II when 17% and 7.4% of the chromatin DNA was rendered acid soluble, respectively. The results suggest that newly acquired exogenous proviral sequences are integrated into both transcriptionally active and inactive regions of chromatin in cells lacking related endogenous viral sequences.
Keywords	proviral sequences mouse ascites sarcoma cells chromatin deoxyribonucleases
Amo Type	Article
Publication Title	Acta Medica Okayama
Published Date	1983-08
Volume	volume37
Issue	issue4
Publisher	Okayama University Medical School
Start Page	283
End Page	289
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
File Version	publisher
Refereed	True
PubMed ID	6312767
Web of Science KeyUT	A1983RE57600002