Anticoagulant substance released from human lung mast cells by stimulation with anti-IgE or Ca-ionophore A23187.

Hayashi, Hisatomo; Tsuda, Takashi; Tsurumi, Naokazu; Takai, Yutaka; Maeda, Masanori; Takahashi, Kiyoshi; Kimura, Ikuro

ID	31744
JaLCDOI	10.18926/AMO/31744
FullText URL	fulltext.pdf 352 KB
Author	Hayashi, Hisatomo Tsuda, Takashi Tsurumi, Naokazu Takai, Yutaka Maeda, Masanori Takahashi, Kiyoshi Kimura, Ikuro
Abstract	A significant amount of anticoagulant substance was released along with histamine, when human lung mast cells were stimulated with anti-IgE and Ca-ionophore A23187. Its activity was lost by heparinase, not by chondroitin-ABC lyase or chondroitin-AC lyase, and also inhibited by Polybrene, suggesting it would be heparin.
Keywords	human lung mast cells heparin anticoagulant activity anti-IgE Ca-ionophore
Amo Type	Article
Publication Title	Acta Medica Okayama
Published Date	1987-04
Volume	volume41
Issue	issue2
Publisher	Okayama University Medical School
Start Page	85
End Page	87
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
File Version	publisher
Refereed	True
PubMed ID	2438904
Web of Science KeyUT	A1987H040200006