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ID 30530
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Author
Tanizaki, Yoshiro
Takahashi, Kiyoshi
Goda, Yoshinori
Sasaki, Yoshihede
Harada, Hiroshi
Kimura, Ikuro
Abstract

Sixty-four patients with confirmed bronchial asthma were treated with HC 20-511 (Ketotifen). HC20-511 was evaluated to be very effective in 6.3%, effective in 50.0% and slightly effective in 10.9% of these patients. The appearance of reactive basophils was inhibited by HC 20-511 in 5 out of 6 cases of reaction to house dust, in all three cases with buckwheat allergy to their allergen and in 7 out of 11 cases to anti-IgE. These results confirm that HC 20-511 inhibits type I allergic reactions induced by specific allergen and IgE.

Keywords
bronchial asthma
ketotifen
basophil reactivity
allergens
anti-IgE
Amo Type
Article
Publication Title
Acta Medica Okayama
Published Date
1980-12
Volume
volume34
Issue
issue6
Publisher
Okayama University Medical School
Start Page
383
End Page
388
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT