| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsutsumi, Koichiro| Otsuka, Motoyuki| |
| Keywords | biomarker early diagnosis high-grade PanIN IPMN liquid biopsy pancreatic ductal carcinoma pancreatic juice small extracellular vesicle treatment |
| Published Date | 2023-03-28 |
| Publication Title | Clinical and Translational Discovery |
| Volume | volume3 |
| Issue | issue2 |
| Publisher | Wiley |
| Start Page | e177 |
| ISSN | 2768-0622 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| DOI | 10.1002/ctd2.177 |
| Web of Science KeyUT | 001224381800004 |
| Related Url | isVersionOf https://doi.org/10.1002/ctd2.177 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Obata, Taisuke| Tsutsumi, Koichiro| Ueta, Eijiro| Oda, Takashi| Kikuchi, Tatsuya| Ako, Soichiro| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Kato, Hironari| Okada, Hiroyuki| Otsuka, Motoyuki| |
| Published Date | 2023-12-12 |
| Publication Title | Molecular Therapy Nucleic Acids |
| Volume | volume34 |
| Publisher | Cell Press |
| Start Page | 102054 |
| ISSN | 2162-2531 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Author(s). |
| File Version | publisher |
| PubMed ID | 38111913 |
| DOI | 10.1016/j.omtn.2023.102054 |
| Web of Science KeyUT | 001146413100001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.omtn.2023.102054 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Morimoto, Kosaku| Matsumoto, Kazuyuki| Obata, Taisuke| Oda, Takashi| Miyamoto, Kazuya| Matsumi, Akihiro| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari| Otsuka, Motoyuki| |
| Keywords | biliary obstruction chemotherapy CT volumetry endoscopic biliary drainage self-expandable metal stent |
| Published Date | 2023 |
| Publication Title | Therapeutic Advances in Gastroenterology |
| Volume | volume16 |
| Publisher | SAGE Publications |
| ISSN | 1756-283X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s), 2023. |
| File Version | publisher |
| PubMed ID | 37900006 |
| DOI | 10.1177/17562848231206980 |
| Web of Science KeyUT | 001097731700001 |
| Related Url | isVersionOf https://doi.org/10.1177/17562848231206980 |
| JaLCDOI | 10.18926/AMO/65974 |
|---|---|
| FullText URL | 77_5_517.pdf |
| Author | Horiguchi, Shigeru| Matsumoto, Kazuyuki| Morimoto, Kosaku| Matsumi, Akihiro| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Tsutsumi, Koichiro| Kato, Hironari| |
| Abstract | We investigated the effect of modified FOLFIRINOX (mFFX) in unresectable pancreatic cancer by retrospectively analyzing the cases of 43 patients who underwent BRCA testing (germline, n=11; somatic, n=26; both germline and somatic, n=6). The association between BRCA mutations and therapeutic effect was clarified. Six patients tested positive for germline pathogenic variants. Familial pancreatic cancer (33% vs. 3%, p=0.006) and peritoneal disseminated lesions (66% vs. 8%, p<0.001) were significantly more common in patients with germline pathogenic variants. The partial response (PR) rate was 100% in the germline BRCA-positive patients, and 27% in the germline BRCA-negative patients (p<0.001). The median progression-free survival (PFS) was not reached for any germline BRCA-positive patients but was 9.0 months for the germline BRCA-negative patients (p=0.042). Patients with stage IV BRCA-associated pancreatic cancer had better overall survival than those with non-BRCA-associated pancreatic cancer, although the difference was nonsignificant (not reached vs. 655 days, p=0.061). Our results demonstrate that a PR and prolonged PFS can be expected in germline BRCA-positive patients after treatment with mFFX. Our findings also suggest that germline BRCA pathogenic variants may be useful as biomarkers for the therapeutic effect of mFFX in patients with pancreatic cancer. |
| Keywords | BRCA FOLFIRINOX pancreatic cancer progression-free survival pathogenic variant |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 517 |
| End Page | 525 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899263 |
| Web of Science KeyUT | 001108661600009 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Miyamoto, Kazuya| Matsumoto, Kazuyuki| Obata, Taisuke| Sato, Ryosuke| Matsumi, Akihiro| Morimoto, Kosaku| Ogawa, Taiji| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari| Otsuka, Motoyuki| |
| Keywords | Balloon-assisted endoscopy Propofol Diazepam Sedation |
| Note | The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-023-02936-8| |
| Published Date | 2023-09-04 |
| Publication Title | BMC Gastroenterology |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 296 |
| ISSN | 1471-230X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37667224 |
| DOI | 10.1186/s12876-023-02936-8 |
| Web of Science KeyUT | 001063014700002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12876-023-02936-8 |
| JaLCDOI | 10.18926/AMO/65494 |
|---|---|
| FullText URL | 77_3_291.pdf |
| Author | Himei, Hitomi| Kato, Hironari| Saragai, Yosuke| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Abstract | We investigated the efficacy and safety of endoscopic plastic stent (PS) placement for hilar benign biliary strictures (BBSs) and compared cases with PS placement above (inside stent, IS) and across (usual stent, US) the sphincter of Oddi. Patients who underwent initial endoscopic PS placement for hilar BBSs between August 2012 and December 2021 were retrospectively analyzed. Hilar BBSs in 88 patients were investigated. Clinical success was achieved in 81 of these cases (92.0%), including 38 patients in the IS group and 43 patients in the US group. Unexpected stent exchange (uSE) before the first scheduled PS exchange occurred in 18 cases (22.2%). The median time from first stent placement to uSE was 35 days. There was no significant difference in the rate and median time to uSE between the two groups. The rates of adverse events such as pancreatitis or cholangitis in the two groups did not significantly differ. However, the rate of difficult stent removal in the IS group (15.8%) was significantly higher than that in the US group (0%) (p=0.0019). US placement is preferable to IS placement for scheduled stent exchange, as it offers the same effectiveness and risk of adverse events with easier stent removal. |
| Keywords | benign biliary stricture inside stent plastic stent |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357630 |
| Web of Science KeyUT | 001026279600007 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fujii, Yuki| Matsumoto, Kazuyuki| Miyamoto, Kazuya| Matsumi, Akihiro| Morimoto, Kosaku| Terasawa, Hiroyuki| Yamazaki, Tatsuhiro| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari| |
| Keywords | biliary stent endoscope migration perforation |
| Published Date | 2022-12-02 |
| Publication Title | MEDICINE |
| Volume | volume101 |
| Issue | issue48 |
| Publisher | LIPPINCOTT WILLIAMS & WILKINS |
| Start Page | e31868 |
| ISSN | 0025-7974 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 the Author(s). |
| File Version | publisher |
| PubMed ID | 36482637 |
| DOI | 10.1097/MD.0000000000031868 |
| Web of Science KeyUT | 000895502600121 |
| Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000031868 |
| FullText URL | fulltext20221130-3.pdf |
|---|---|
| Author | Sato, Ryosuke| Matsumoto, Kazuyuki| Kanzaki, Hiromitsu| Matsumi, Akihiro| Miyamoto, Kazuya| Morimoto, Kosaku| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Tsutsumi, Koichiro| Horiguchi, Shigeru| Kato, Hironari| |
| Keywords | Endoscopic ultrasound-guided fine needle aspiration Linitis plastica Autoimmune pancreatitis Paraneoplastic syndromes Case report |
| Note | Sato R, Matsumoto K, Kanzaki H, Matsumi A, Miyamoto K, Morimoto K, Terasawa H, Fujii Y, Yamazaki T, Uchida D, Tsutsumi K, Horiguchi S, Kato H. Gastric linitis plastica with autoimmune pancreatitis diagnosed by an endoscopic ultrasonography-guided fine-needle biopsy: A case report. World J Clin Cases 2022; 10(31): 11607-11616 [PMID: 36387831 DOI: 10.12998/wjcc.v10.i31.11607]| |
| Published Date | 2022-11-6 |
| Publication Title | World Journal of Clinical Cases |
| Volume | volume10 |
| Issue | issue31 |
| Publisher | Baishideng Publishing Group Inc. |
| Start Page | 11607 |
| End Page | 11616 |
| ISSN | 2307-8960 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 36387831 |
| DOI | 10.12998/wjcc.v10.i31.11607 |
| Web of Science KeyUT | 000885256200043 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tanaka, Emi| Ogawa, Tsuneyoshi| Tsutsumi, Koichiro| Kobayashi, Sayo| Nawa, Toru| Ueki, Toru| Okada, Hiroyuki| |
| Keywords | intraductal papillary mucinous carcinoma intraductal papillary mucinous neoplasm pancreatic exocrine insufficiency pancreatic cancer leg edema pancrelipase |
| Published Date | 2022-07-01 |
| Publication Title | Internal Medicine |
| Volume | volume61 |
| Issue | issue13 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 1963 |
| End Page | 1967 |
| ISSN | 0918-2918 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 34840231 |
| DOI | 10.2169/internalmedicine.8611-21 |
| Web of Science KeyUT | 000823068800001 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.8611-21 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamazaki, Tatsuhiro| Tomoda, Takeshi| Kato, Hironari| Miyamoto, Kazuya| Matsumi, Akihiro| Ueta, Eijiro| Fujii, Yuki| Saragai, Yosuke| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Keywords | surveillance prognosis factor intraductal papillary mucinous neoplasm pancreatic cancer |
| Published Date | 2021-10-15 |
| Publication Title | Internal Medicine |
| Volume | volume60 |
| Issue | issue20 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 3205 |
| End Page | 3211 |
| ISSN | 0918-2918 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 33967138 |
| DOI | 10.2169/internalmedicine.7168-21 |
| Web of Science KeyUT | 000709798800002 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.7168-21 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Obata, Taisuke| Tsutsumi, Koichiro| Kato, Hironari| Ueki, Toru| Miyamoto, Kazuya| Yamazaki, Tatsuhiro| Matsumi, Akihiro| Fujii, Yuki| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Yasugi, Kengo| Ogawa, Tsuneyoshi| Takenaka, Ryuta| Okada, Hiroyuki| |
| Keywords | bile duct stone endoscopic retrograde cholangiography Roux-en-Y anastomosis short-type balloon enteroscopy complete stone removal gastrectomy |
| Published Date | 2021-07-27 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume10 |
| Issue | issue15 |
| Publisher | MDPI |
| Start Page | 3314 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34362098 |
| DOI | 10.3390/jcm10153314 |
| Web of Science KeyUT | 000682079900001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm10153314 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ueta, Eijiro| Tsutsumi, Koichiro| Kato, Hironari| Matsushita, Hiroshi| Shiraha, Hidenori| Fujii, Masakuni| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Published Date | 2021-06-10 |
| Publication Title | Scientific Reports |
| Volume | volume11 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 12298 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021 |
| File Version | publisher |
| PubMed ID | 34112884 |
| DOI | 10.1038/s41598-021-91804-0 |
| Web of Science KeyUT | 000663785600048 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-021-91804-0 |
| FullText URL | fulltext20210602-5.pdf Supplemental_Tables20210602-5.pdf figures_all.pdf |
|---|---|
| Author | Fujii, Yuki| Matsumoto, Kazuyuki| Kato, Hironari| Yamazaki, Tatsuhiro| Tomoda, Takeshi| Horiguchi, Shigeru| Tsutsumi, Koichiro| Nishida, Kenji| Tanaka, Takehiro| Hanada, Keiji| Okada, Hiroyuki| |
| Keywords | Endoscopic ultrasound Subtype Intraductal papillary mucinous neoplasm |
| Note | © 2021 IAP and EPC. Published by Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.pan.2021.01.026] . | |
| Published Date | 2021-4 |
| Publication Title | Pancreatology |
| Volume | volume21 |
| Issue | issue3 |
| Publisher | Elsevier BV |
| Start Page | 622 |
| End Page | 629 |
| ISSN | 1424-3903 |
| NCID | AA11583711 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 33640249 |
| DOI | 10.1016/j.pan.2021.01.026 |
| Web of Science KeyUT | 000641072700016 |
| Related Url | isVersionOf https://doi.org/10.1016/j.pan.2021.01.026 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsutsumi, Koichiro| Ueki, Toru| Noma, Yasuhiro| Omonishi, Kunihiro| Ohno, Kyotaro| Kawahara, Soichiro| Oda, Takashi| Kato, Hironari| Okada, Hiroyuki| |
| Keywords | EUS-FNB ICDC Sample area Good-quality tissue |
| Published Date | 2021-01-07 |
| Publication Title | BMC Gastroenterology |
| Volume | volume21 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 21 |
| ISSN | 1471-230X |
| NCID | AA12034934 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021. |
| File Version | publisher |
| PubMed ID | 33413133 |
| DOI | 10.1186/s12876-020-01590-8 |
| Web of Science KeyUT | 000608240100002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12876-020-01590-8 |
| FullText URL | fulltext.pdf Fig_1-4.pdf |
|---|---|
| Author | Ishihara, Yuki| Matsumoto, Kazuyuki| Kato, Hironari| Tsutsumi, Koichiro| Tomoda, Takeshi| Matsumi, Akihiro| Miyamoto, Kazuya| Yamazaki, Tatsuhiro| Saragai, Yosuke| Fujii, Yuki| Uchida, Daisuke| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Keywords | Peroral direct cholangioscopy Hepatolithiasis Altered gastrointestinal anatomy Double-balloon endoscopy |
| Note | This is an Accepted Manuscript of an article published by Springer.| |
| Published Date | 2020-11-02 |
| Publication Title | Surgical Endoscopy |
| Volume | volume35 |
| Publisher | Springer |
| Start Page | 1895 |
| End Page | 1902 |
| ISSN | 0930-2794 |
| NCID | AA10750363 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 33140150 |
| DOI | 10.1007/s00464-020-08139-6 |
| Web of Science KeyUT | 000584333800003 |
| Related Url | isVersionOf https://doi.org/10.1007/s00464-020-08139-6 |
| FullText URL | fulltext.pdf Figure.tif |
|---|---|
| Author | Tomoda, Takeshi| Kato, Hironari| Miyamoto, Kazuya| Matsumi, Akihiro| Ueta, Eijiro| Fujii, Yuuki| Saragai, Yousuke| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Keywords | diclofenac low dose post‐ERCP pancreatitis |
| Note | This is the peer reviewed version of the following article: Takeshi Tomoda et. al. Efficacy of low dose rectal diclofenac for preventing post‐endoscopic retrograde cholangiopancreatography pancreatitis: Propensity score‐matched analysis. Digestive Endoscopy, which has been published in final form at https://doi.org/10.1111/den.13828. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.| |
| Published Date | 2020-09-02 |
| Publication Title | Digestive Endoscopy |
| Volume | volume33 |
| Publisher | Wiley |
| Start Page | 656 |
| End Page | 662 |
| ISSN | 0915-5635 |
| NCID | AA10907137 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 32881078 |
| DOI | 10.1111/den.13828 |
| Web of Science KeyUT | 000577757600001 |
| Related Url | isVersionOf https://doi.org/10.1111/den.13828 |
| FullText URL | text_correction.pdf table3_correction.pdf |
|---|---|
| Author | Tomoda, Takeshi | Kato, Hironari| Miyamoto, Kazuya| Matsumi, Akihiro| Ueta, Eijiro| Fujii, Yuuki| Saragai, Yousuke| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Note | Correction to: Surgical Endoscopy https://doi.org/10.1007/s00464-020-07385-y| |
| Published Date | 2020-02-06 |
| Publication Title | Surgical Endoscopy |
| Volume | volume35 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 239 |
| End Page | 240 |
| ISSN | 09302794 |
| NCID | AA10750363 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 32030547 |
| DOI | 10.1007/s00464-020-07399-6 |
| Web of Science KeyUT | 000515963500002 |
| Related Url | isVersionOf https://doi.org/10.1007/s00464-020-07399-6 |
| JaLCDOI | 10.18926/AMO/54605 |
|---|---|
| FullText URL | 70_5_417.pdf |
| Author | Mizukawa, Sho| Kato, Hironari| Muro, Shinichiro| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Matsumoto, Kazuyuki| Yamamoto, Naoki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| Inoue, Hirofumi| Tanaka, Noriyuki| |
| Abstract | Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is a standard procedure for precise histological diagnosis of pancreas tumors, but it is sometimes difficult to obtain adequate specimens. EUS Sonopsy CY® is a newly designed needle with original features. This randomized study will compare the tissue collection rate of EUS Sonopsy CY® to that of a conventional needle in EUS-FNA. The major eligibility criteria are as follows: Patients with a pancreatic mass referred for EUSFNA; age ≥20 years, and performance status＜4. The primary outcome is the tissue collection rate. This study will elucidate the efficacy of EUS Sonopsy CY®. |
| Keywords | endoscopic ultrasound-guided fine needle aspiration pancreatic cancer Menghini type needle tip |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-10 |
| Volume | volume70 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 417 |
| End Page | 420 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27777439 |
| Web of Science KeyUT | 000388098700016 |
| JaLCDOI | 10.18926/AMO/54513 |
|---|---|
| FullText URL | 70_4_323.pdf |
| Author | Yamamoto, Naoki| Kato, Hironari| Mizukawa, Sho| Muro, Shinichiro| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Abstract | Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) with contrast agent enabled us to assess the hemodynamics closely, despite limited data in pancreatic tumors. We have initiated a prospective, single arm, and non-randomized study to clarify the accuracy and safety of CH-EUS with Sonazoid and time-intensity curve (TIC) analysis for diagnosing benign or malignant pancreatic tumors. A total of 200 patients will undergo CH-EUS and TIC analysis. Receiver operating characteristic (ROC) analysis will be used to determine the optimal parameter cutoff values for TIC analysis. This will clarify whether CH-EUS and TIC can further improve the diagnosis of pancreatic tumors over conventional EUS. |
| Keywords | CH-EUS pancreatic tumor TIC |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 323 |
| End Page | 325 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549682 |
| Web of Science KeyUT | 000384748600017 |
| JaLCDOI | 10.18926/AMO/54511 |
|---|---|
| FullText URL | 70_4_313.pdf |
| Author | Matsumoto, Kazuyuki| Kato, Hironari| Tsutsumi, Koichiro| Mizukawa, Sho| Yabe, Syuntaro| Seki, Hiroyuki| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Yamamoto, Naoki| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Abstract | Recently, endoscopic ultrasonography (EUS)-guided ethanol ablation for small pancreatic neuroendocrine tumors (p-NETs) has been reported. However, the efficacy and safety of the technique remain unclear. We have launched a prospective pilot study of EUS-guided ethanol ablation for p-NETs. The major eligibility criteria are the presence of a pathologically diagnosed grade (G) 1 or G2 p-NET, a tumor size of 2cm, and being a poor candidate for surgery. A total of 5 patients will be treated. The primary endpoint will be the complete ablation rate at 1 month after treatment. |
| Keywords | pancreatic neuroendocrine tumor ethanol ablation EUS-guided |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 313 |
| End Page | 316 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549680 |
| Web of Science KeyUT | 000384748600015 |
