ID | 62411 |
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Ahmed, Feroz
Graduate School of Natural Science and Technology, Department of Medical Bioengineering, Okayama University
Yoshida, Yuichi
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Department of Medical Bioengineering, Okayama University
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Wang, Jin
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Department of Medical Bioengineering, Okayama University
Sakai, Kenji
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Department of Medical Bioengineering, Okayama University
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Kiwa, Toshihiko
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Department of Medical Bioengineering, Okayama University
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Abstract | The internal fluidic parameters of microfluidic channels must be analyzed to solve fundamental microfluidic problems, including microscale transport problems involving thermal analysis, chemical reactivity, velocity, pressure drop, etc., for developing good-quality chemical and biological products. Therefore, the characterization and optimization of the interaction of chemical and biological solutions through microfluidic channels are vital for fluid flow design and engineering for quality assurance in microfluidic platforms. As the internal structures and kinetics of microfluidic channels are becoming increasingly complex, experiments involving optimal fluidic and transport designs are challenging to perform with high accuracy. However, highly integrated simulation tools can guide researchers without specialized computational fluid backgrounds to design numerical prototypes of highly integrated devices. In this study, a microfluidic chip with two inlet wells and one outlet well was fabricated from polydimethylsiloxane following which simulations were performed using an ANSYS Fluent tool influenced by computational fluid dynamics at a nearly identical scale. The pressure drop and velocity profiles of the interaction of two pH buffer solutions (pH 4 and 10) through the designed microfluidic chip were qualitatively estimated from experimental data analysis and validated with the simulation results obtained from the CFD-influenced ANSYS Fluent tool.
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Published Date | 2021-07-26
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Publication Title |
AIP Advances
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Volume | volume11
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Issue | issue7
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Publisher | AIP Publishing
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Start Page | 75224
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ISSN | 2158-3226
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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Copyright Holders | © 2021 Author(s).
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File Version | publisher
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DOI | |
Web of Science KeyUT | |
Related Url | isVersionOf https://doi.org/10.1063/5.0056597
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License | http://creativecommons.org/licenses/by/4.0/
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