ID | 13178 |
Eprint ID | 13178
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FullText URL | |
Title Alternative | Effects of oral morphine for pain relief of peripheral arterial disease
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Author |
Matsusaki, Takashi
Miyake, Asako
Kaku, Ryuji
Sato, Kenji
Matsumi, Masaki
Kiyoshi, Morita
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Abstract | Peripheral arterial disease often causes ischemic ulcers due to impaired blood flow and consequentially induces intractable pain. For these patients, we have recently begun to administer morphine orally. In this study, we retrospectively examined the effects of oral morphine for the relief of pain caused by peripheral arterial disease.
Oral morphine was administered to 17 cases of peripheral arterial disease between January, 2004 and February, 2006. The initial dosage was 5 mg or 10 mg, started on an as-needed basis. After the daily dosage of morphine became constant, we divided the dosage into four or six times a day and administered it regularly. With the exception of one case, a small amount of oral morphine, from 20 mg to 70 mg a day, could alleviate patient's pain. Eight cases had side effects such as nausea, constipation or drowsiness.
Oral morphine is effective for pain relief of peripheral arterial disease patients. However, now in Japan, oral morphine, which we can prescribe for those patients with insurance, has a shorter duration of action, so we need to administer slow-release morphine. Oral morphine must be administered carefully because many peripheral arterial disease patients have cardiac disease or renal dysfunction as complications.
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Keywords | 末梢血行障害 (peripheral arterial disease)
モルヒネ (oral morphine)
疼痛管理 (pain management)
虚血性潰瘍 (ischemic ulcer)
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Note | 原著
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Published Date | 2007-05-01
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Publication Title |
岡山医学会雑誌
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Publication Title Alternative | Journal of Okayama Medical Association
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Volume | volume119
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Issue | issue1
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Publisher | 岡山医学会
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Publisher Alternative | Okayama Medical Association
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Start Page | 57
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End Page | 60
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ISSN | 00301558
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NCID | AN00032489
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Content Type |
Journal Article
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language |
Japanese
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Copyright Holders | 岡山医学会
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File Version | publisher
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Refereed |
True
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DOI | |
Eprints Journal Name | joma
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