| FullText URL | fulltext.pdf |
|---|---|
| Author | Fujihara, Miwa| Shien, Tadahiko| Shien, Kazuhiko| Suzawa, Ken| Takeda, Tatsuaki| Zhu, Yidan| Mamori, Tomoka| Otani, Yusuke| Yoshioka, Ryo| Uno, Maya| Suzuki, Yoko| Abe, Yuko| Hatono, Minami| Tsukioki, Takahiro| Takahashi, Yuko| Kochi, Mariko| Iwamoto, Takayuki| Taira, Naruto| Doihara, Hiroyoshi| Toyooka, Shinichi| |
| Keywords | breast cancer YES1 T-DM1 dasatinib drug resistance |
| Published Date | 2021-11-26 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume22 |
| Issue | issue23 |
| Publisher | MDPI |
| Start Page | 12809 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34884609 |
| DOI | 10.3390/ijms222312809 |
| Web of Science KeyUT | 000735641400001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms222312809 |
| JaLCDOI | 10.18926/AMO/60799 |
|---|---|
| FullText URL | 74_5_401.pdf |
| Author | Tsukioki, Takahiro| Shien, Tadahiko| Ohtani, Yusuke| Fujihara, Miwa| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi| |
| Abstract | Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC. |
| Keywords | differentiated thyroid carcinoma juvenile children |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-10 |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 401 |
| End Page | 406 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106695 |
| Web of Science KeyUT | 000581970100004 |
| NAID | 120006892925 |
| FullText URL | CCP_fulltext.pdf |
|---|---|
| Author | Tsukioki, Takahiro| Shien, Tadahiko| Tanaka, Takehiro| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi| Toyooka, Shinichi| |
| Keywords | Breast cancer Metformin Preoperative Tils CD8 PD-L1 |
| Published Date | 2020-06-12 |
| Publication Title | Cancer Chemotherapy and Pharmacology |
| Volume | volume86 volume86 |
| Issue | issue1 issue1 |
| Publisher | Springer |
| Start Page | 55 55 |
| End Page | 63 63 |
| ISSN | 0344-5704 |
| NCID | AA00598397 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©Author(s) |
| File Version | publisher |
| PubMed ID | 32533334 |
| DOI | 10.1007/s00280-020-04092-2 |
| Web of Science KeyUT | 000539841500002 |
| Related Url | isVersionOf https://doi.org/10.1007/s00280-020-04092-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Suzuki, Yoko| Taniguchi, Kohei| Hatono, Minami| Kajiwara, Yukiko| Abe, Yuko| Kawada, Kengo| Tsukioki, Takahiro| Kochi, Mariko| Nishiyama, Keiko| Iwamoto, Takayuki| Ikeda, Hirokuni| Shien, Tadahiko| Taira, Naruto| Tabata, Masahiro| Yanai, Hiroyuki| Doihara, Hiroyoshi| |
| Keywords | Radiation-induced angiosarcoma Radiotherapy Breast-conserving surgery Breast cancer Paclitaxel therapy Adjuvant therapy of angiosarcoma |
| Published Date | 2020-01-16 |
| Publication Title | Surgical Case Reports |
| Volume | volume6 |
| Issue | issue1 |
| Publisher | SpringerOpen |
| Start Page | 25 |
| ISSN | 2198-7793 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2020 |
| File Version | publisher |
| PubMed ID | 31950295 |
| DOI | 10.1186/s40792-020-0790-7 |
| Web of Science KeyUT | 000513920900001 |
| Related Url | isVersionOf https://doi.org/10.1186/s40792-020-0790-7 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takahashi, Yuko| Iwamoto, Takayuki| Suzuki, Yoko| Kajiwara, Yukiko| Hatono, Minami| Tsukioki, Takahiro| Kawada, Kengo| Kochi, Mariko| Ikeda, Hirokuni| Shien, Tadahiko| Taira, Naruto| Matsuoka, Junji| Doihara, Hiroyoshi| Toyooka, Shinichi| |
| Keywords | Gene expression Hormone receptor positive Residual tumor burden Targeted therapy Triple negative |
| Published Date | 2020-04 |
| Publication Title | Clinical Breast Cancer |
| Volume | volume20 |
| Issue | issue2 |
| Publisher | Elsevier |
| Start Page | 117 |
| End Page | 124 |
| ISSN | 1526-8209 |
| NCID | AA11694891 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31570267 |
| DOI | 10.1016/j.clbc.2019.07.001 |
| Web of Science KeyUT | 000529805200021 |
| Related Url | isVersionOf https://doi.org/10.1016/j.clbc.2019.07.001 |
