FullText URL | fulltext.pdf |
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Author | Nakamura, Keiichiro| Matsuoka, Hirofumi| Kubo, Kotaro| Shirakawa, Shinsuke| Ida, Naoyuki| Haraga, Junko| Ogawa, Chikako| Okamoto, Kazuhiro| Nagao, Shoji| Masuyama, Hisashi| |
Keywords | returning to the same workplace gynecologic neoplasms sick leave |
Published Date | 2023-11-23 |
Publication Title | Japanese Journal of Clinical Oncology |
Volume | volume54 |
Issue | issue3 |
Publisher | Oxford University Press (OUP) |
Start Page | 292 |
End Page | 296 |
ISSN | 1465-3621 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2023. |
File Version | publisher |
PubMed ID | 37995280 |
DOI | 10.1093/jjco/hyad159 |
Web of Science KeyUT | 001108594700001 |
Related Url | isVersionOf https://doi.org/10.1093/jjco/hyad159 |
FullText URL | fulltext.pdf |
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Author | Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Ogawa, Chikako| Masuyama, Hisashi| Tabuchi, Takahiro| |
Keywords | cervical cancer screening social inequality screening hesitation internet survey |
Published Date | 2024-02-13 |
Publication Title | International Journal of General Medicine |
Volume | volume17 |
Publisher | Dove Press |
Start Page | 541 |
End Page | 551 |
ISSN | 1178-7074 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 Mitoma et al. |
File Version | publisher |
PubMed ID | 38371520 |
DOI | 10.2147/IJGM.S453675 |
Web of Science KeyUT | 001162765400001 |
Related Url | isVersionOf https://doi.org/10.2147/IJGM.S453675 |
JaLCDOI | 10.18926/AMO/63406 |
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FullText URL | 76_2_129.pdf |
Author | Kubo, Kotaro| Nakamura, Keiichiro| Okamoto, Kazuhiro| Matsuoka, Hirofumi| Ida, Naoyuki| Haruma, Tomoko| Ogawa, Chikako| Masuyama, Hisashi| |
Abstract | Cancer patients have increased risk of venous thromboembolism (VTE) that must be assessed before treatment. This study aimed to determine effective VTE biomarkers in gynecologic cancer (GC). We investigated the correlation between D-dimer levels, Khorana risk score (KRS), Glasgow prognostic score (GPS), and VTE in 1499 GC patients (583 cervical cancer (CC), 621 endometrial cancer (EC), and 295 ovarian cancer (OC) patients) treated at our institution between January 2008 and December 2019. χ2 and Mann–Whitney U-tests were used to determine statistical significance. We used receiver operating characteristic-curve analysis to evaluate the discriminatory ability of each parameter. D-dimer levels were significantly correlated with KRS and GPS in patients with GC. VTE was diagnosed in 11 CC (1.9%), 27 EC (4.3%), and 39 OC patients (13.2%). Optimal D-dimer cut-off values for VTE were 3.1, 3.2, and 3.9 μg/ml in CC, EC and OC patients, respectively. D-dimer could significantly predict VTE in all GC patients. Furthermore, D-dimer combined with GPS was more accurate in predicting VTE than other VTE biomarkers in stage IIIC and IVA OC (AUC: 0.846; p<0.001). This study demonstrates that combined D-dimer and GPS are useful in predicting VTE in patients with OC. |
Keywords | D-dimer gynecologic cancer venous thromboembolism |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2022-04 |
Volume | volume76 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 129 |
End Page | 135 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 35503440 |
Web of Science KeyUT | 000792374900004 |
JaLCDOI | 10.18926/AMO/62816 |
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FullText URL | 75_6_745.pdf |
Author | Hayata, Kei| Mishima, Sakurako| Ohira, Akiko| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Ogawa, Chikako| Masuyama, Hisashi| |
Abstract | NIPT is non-definitive testing to estimate the possibility that fetuses have trisomy 21, trisomy 18, or trisomy 13. However, in NIPT-positive and indeterminate cases, rare chromosomal disease may become apparent, requiring advanced genetic considerations and counseling skills. We experienced two such cases, a trisomy 21 mosaicism case triggered by NIPT-positive status and 18q deletion syndrome triggered by NIPT-indeterminate status. These cases have two clinical implications for NIPT. First, it was revealed that trisomy mosaicism might be found in NIPT-positive cases that have lower Z-Scores than those inferred from the fraction of fetal cfDNA in the case of standard trisomy. Second, it is possible that microdeletion syndrome could be the reason for an indeterminate NIPT result. Today’s genetic counseling requires more expertise in ethics and communication as well as genetic science because NIPT can lead to totally unexpected results. |
Keywords | NIPT massively parallel sequencing trisomy 21 mosaicism 18q-deletion syndrome genetic counseling |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2021-12 |
Volume | volume75 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 745 |
End Page | 750 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34955544 |
Web of Science KeyUT | 000735319800002 |
NAID | 120007180276 |
FullText URL | fulltext.pdf |
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Author | Okamoto, Kazuhiro| Nakamura, Keiichiro| Matsuoka, Hirofumi| Matsubara, Yuko| Haraga, Junko| Ogawa, Chikako| Masuyama, Hisashi| |
Keywords | gynecological cancer chronic diseases occurrence risk factors |
Published Date | 2020-01-29 |
Publication Title | Molecular and Clinical Oncology |
Volume | volume12 |
Issue | issue4 |
Publisher | Spandidos Publications |
Start Page | 336 |
End Page | 342 |
ISSN | 2049-9450 |
NCID | AA12610944 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Okamoto et al. |
File Version | publisher |
PubMed ID | 32190316 |
DOI | 10.3892/mco.2020.1989 |
Web of Science KeyUT | 000523727300007 |
Related Url | isVersionOf https://doi.org/10.3892/mco.2020.1989 |
JaLCDOI | 10.18926/AMO/58268 |
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FullText URL | 74_2_109.pdf |
Author | Ogawa, Chikako| Nakamura, Keiichiro| Matsuoka, Hirofumi| Matsubara, Yuko| Haraga, Junko| Masuyama, Hisashi| |
Abstract | This study aimed to determine whether the risk conferred by gynecologic cancer (GC) as second primary cancer (SPC) differs from that associated with GC as first primary cancer (FPC). We investigated the correlations between FPC/SPC and the characteristics and prognoses of 1,645 GC patients (701 with cervical cancer [CC], 641 with endometrial cancer [EM], and 303 with ovarian cancer [OV]). The χ2 test and the Kaplan–Meier method were used to determine whether FPC/SPC and the characteristics and prognoses of GC patients. Of the SPC patients, 26 (3.7%) had CC, 53 (8.3%) had EM, and 31 (10.2%) had OV. The most common previous cancer type in SPC of GC patients was breast cancer, which was observed in 13 patients (50.0%) with CC, 23 (43.4%) with EM, and 16 (51.6%) with OV. In all patients with CC, EM, and OV as SPC, the stage was significantly associated with recurrence. There were no significant differences in the morbidity or mortality of CC, EM, or OV patients between those with FPC and those with SPC. The risk of SPC development in GC patients varied, ranging from 3.5% (CC) to 10.3% (OV) of patients. |
Keywords | second primary cancer gynecologic cancer prognosis |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-04 |
Volume | volume74 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 109 |
End Page | 114 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32341584 |
Web of Science KeyUT | 000528278500003 |
NAID | 120006839447 |
Title Alternative | A preoperative SUVmax greater than the ADCmin of the primary tumour : A predictor of disease recurrence and survival in patients with endometrial cancer |
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FullText URL | 126_11.pdf |
Author | Nakamura, Keiichiro| Joja, Ikuo| Fukushima, Chikako| Haruma, Tomoko| Hayashi, Chiaki| Kusumoto, Tomoyuki| Seki, Noriko| Hongo, Atsushi| Hiramatsu, Yuji| |
Keywords | endometrial cancer SUVmax PET/CT predictor of poor prognosis |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-04-01 |
Volume | volume126 |
Issue | issue1 |
Start Page | 11 |
End Page | 15 |
ISSN | 0030-1558 |
Related Url | http://www.okayama-u.ac.jp/user/oma/ |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.11 |