ID | 53340 |
JaLCDOI | |
FullText URL | |
Author |
Inada, Ryo
Toshima, Toshiaki
Mori, Yoshiko
Kishimoto, Hiroyuki
Kaken ID
Oshiro, Taihei
Kanemitsu, Yukihide
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Abstract | A case of advanced rectal cancer treated by aggressive local and systemic treatment who has survived more than 7 years from initial recurrence is presented. A 55-year-old woman was diagnosed with advanced lower rectal cancer and underwent a low anterior resection with complete removal of all regional lymph nodes and total mesorectal excision. The tumor was diagnosed as a moderately differentiated adenocarcinoma, pStage IIIB (T3, N2a, M0). Twenty-six months after the initial surgery, local recurrence in the pelvis was detected by computed tomography, and total pelvic exenteration with distal sacrectomy (TPES) was performed after systemic chemotherapy with a molecular-targeted drug. Six months after the TPES, multiple lung metastases were detected. Consequently, the patient underwent radiofrequency ablation (RFA) and chemotherapy. The disease has since been controlled for 38 months. As volume control is essential for cancer treatment, it may be important to combine appropriate local therapy with systemic therapy to metastatic or recurrent sites in order to achieve much longer disease control.
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Keywords | colorectal cancer
recurrence
total pelvic exenteration
radiofrequency ablation
systemic chemotherapy
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Amo Type | Case Report
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Publication Title |
Acta Medica Okayama
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Published Date | 2015-04
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Volume | volume69
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Issue | issue2
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Publisher | Okayama University Medical School
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Start Page | 113
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End Page | 118
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School
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File Version | publisher
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Refereed |
True
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PubMed ID | |
Web of Science KeyUT |