ID | 62339 |
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Author |
Tsuchida-Nishiwaki, Mariko
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
Uchida, Haruhito A.
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
Takeuchi, Hidemi
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
Nishiwaki, Noriyuki
Department of Gastroenterological Surgery Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
Maeshima, Yohei
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
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Saito, Chie
Department of Nephrology, Faculty of Medicine, University of Tsukuba
Sugiyama, Hitoshi
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
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Wada, Jun
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science
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Narita, Ichiei
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science
Watanabe, Tsuyoshi
Tokyo-Kita Medical Center
Matsuo, Seiichi
Nagoya University
Hishida, Akira
Yaizu City Hospital
Yamagata, Kunihiro
Department of Nephrology, Faculty of Medicine, University of Tsukuba
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Abstract | It is well-known that hypertension exacerbates chronic kidney disease (CKD) progression, however, the optimal target blood pressure (BP) level in patients with CKD remains unclear. This study aimed to assess the optimal BP level for preventing CKD progression. The risk of renal outcome among different BP categories at baseline as well as 1 year after, were evaluated using individual CKD patient data aged between 40 and 74 years from FROM-J [Frontier of Renal Outcome Modifications in Japan] study. The renal outcome was defined as >= 40% reduction in estimated glomerular filtration rate to<60 mL/min/1.73 m(2), or a diagnosis of end stage renal disease. Regarding baseline BP, the group of systolic BP (SBP) 120-129 mmHg had the lowest risk of the renal outcome, which increased more than 60% in SBP
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Published Date | 2021-07-22
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Publication Title |
Scientific Reports
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Volume | volume11
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Issue | issue1
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Publisher | Nature Portfolio
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Start Page | 14990
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ISSN | 2045-2322
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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Copyright Holders | © The Author(s) 2021
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File Version | publisher
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Related Url | isVersionOf https://doi.org/10.1038/s41598-021-94467-z
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License | http://creativecommons.org/licenses/by/4.0/
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