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Author Fithroni, Abdul Basith| Kobayashi, Kazuko| Uji, Hirotaka| Ishimoto, Manabu| Akehi, Masaru| Ohtsuki, Takashi| Matsuura, Eiji|
Keywords boron neutron capture therapy (BNCT) biologically self-degradable amphipathic polymer (Lactosome) hydrophobic boron cluster carborane isomers or o-carborane alkylated derivatives molecular glue effect
Published Date 2022-10-21
Publication Title CELLS
Volume volume11
Issue issue20
Publisher MDPI
Start Page 3307
ISSN 2073-4409
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36291173
DOI 10.3390/cells11203307
Web of Science KeyUT 000872497500001
Related Url isVersionOf https://doi.org/10.3390/cells11203307
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Author Tabuchi, Masako| Inoue, Katsumi| Usui-Kataoka, Hitomi| Kobayashi, Kazuko| Teramoto, Misako| Takasugi, Koji| Shikata, Kenichi| Yamamura, Masahiro| Ando, Kenji| Nishida, Keiichiro| Kasahara, Junko| Kume, Noriaki| Lopez, Luis R.| Mitsudo, Kazuaki| Nobuyoshi, Masakiyo| Yasuda, Tatsuji| Kita, Toru| Makino, Hirofumi| Matsuura, Eiji|
Keywords beta 2-glycoprotein I oxidized LDL/beta 2-glycoprotein I complexes diabetes mellitus oxidized LDL
Published Date 2007-04
Publication Title Journal Of Lipid Research
Volume volume48
Issue issue4
Publisher ELSEVIER
Start Page 768
End Page 781
ISSN 0022-2275
NCID AA00701215
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2007 by the American Society for Biochemistry and Molecular Biology, Inc.
File Version publisher
PubMed ID 17261875
DOI 10.1194/jlr.M600414-JLR200
Web of Science KeyUT 000245627100003
Related Url isVersionOf https://doi.org/10.1194/jlr.M600414-JLR200
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Author Kobayashi, Kazuko| Kishi, Makoto| Atsumi, Tatsuya| Bertolaccini, Maria L.| Makino, Hirofumi| Sakairi, Nobuo| Yamamoto, Itaru| Yasuda, Tatsuji| Khamashta, Munther A.| Hughes, Graham R. V.| Koike, Takao| Voelker, Dennis R.| Matsuura, Eiji|
Keywords antiphospholipid syndrome arterial thrombosis autoantibody
Published Date 2003-04
Publication Title Journal Of Lipid Research
Volume volume44
Issue issue4
Publisher Elsevier
Start Page 716
End Page 726
ISSN 0022-2275
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2003 by Lipid Research, Inc.
File Version publisher
PubMed ID 12562869
DOI 10.1194/jlr.M200329-JLR200
Web of Science KeyUT 000182214500007
Related Url isVersionOf https://doi.org/10.1194/jlr.M200329-JLR200
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Author Liu, Qingping| Kobayashi, Kazuko| Furukawa, Jun-ichi| Inagaki, Junko| Sakairi, Nobuo| Iwado, Akimasa| Yasuda, Tatsuji| Koike, Takao| Voelker, Dennis R.| Matsuura, Eiji|
Keywords antiphospholipid syndrome atherosclerosis autoantibody beta(2)-glycoprotein I oxidized LDL omega-oxidation
Published Date 2002-09
Publication Title Journal Of Lipid Research
Volume volume43
Issue issue9
Publisher Elsevier
Start Page 1486
End Page 1495
ISSN 0022-2275
NCID AA00701215
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2002 by Lipid Research, Inc.
File Version publisher
PubMed ID 12235181
DOI 10.1194/jlr.M20063-JLR200
Web of Science KeyUT 000178252900016
Related Url isVersionOf https://doi.org/10.1194/jlr.M20063-JLR200
FullText URL fulltext20210421_2.pdf
Author Lim, Melissa Siaw Han| Nishiyama, Yuki| Ohtsuki, Takashi| Watanabe, Kazunori| Kobuchi, Hirotsugu| Kobayashi, Kazuko| Matsuura, Eiji|
Keywords Lactosome ABCG2 siRNA Cancer siRNA delivery Photodynamic therapy Polymeric micelle Photosensitizer Photochemical internalization
Note ©2021 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.xphs.2021.01.026] . |
Published Date 2021-04-30
Publication Title Journal of Pharmaceutical Sciences
Volume volume110
Publisher Elsevier
Start Page 1788
End Page 1798
ISSN 00223549
NCID AA00704450
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 33529684
DOI 10.1016/j.xphs.2021.01.026
Web of Science KeyUT 000631863100036
Related Url isVersionOf https://doi.org/10.1016/j.xphs.2021.01.026
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Author Lim, Melissa Siaw Han| Ohtsuki, Takashi| Takenaka, Fumiaki| Kobayashi, Kazuko| Akehi, Masaru| Uji, Hirotaka| Kobuchi, Hirotsugu| Sasaki, Takanori| Ozeki, Eiichi| Matsuura, Eiji|
Keywords theranostics single chain variable fragment of IgG (scFv) drug delivery system (DDS) photodynamic therapy (PDT) PET imaging accelerated blood clearance (ABC) cell penetrating peptide (CPP) siRNA ATP-binding cassette subfamily G member 2 (ABCG2)
Published Date 2021-02-18
Publication Title Life
Volume volume11
Issue issue2
Publisher MDPI
Start Page 158
ISSN 2075-1729
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 33670777
DOI 10.3390/life11020158
Web of Science KeyUT 000622756700001
Related Url isVersionOf https://doi.org/10.3390/life11020158
Author Xian, Wen Tan| Kobayashi, Kazuko| Lianhua, Shen| Inagaki, Junko| Ide, Masahiro| Hwang, Siaw San| Matsuura, Eiji|
Keywords Food science Food analysis Rice bran extract (RBE) Functional food Phytochemicals Atherosclerosis Oxidative stress Inflammation Antioxidant Anti-inflammation Oxidized lipoprotein (oxLDL)
Published Date 2020-12
Publication Title Heliyon
Volume volume6
Issue issue12
Publisher Elsevier
Start Page e05743
ISSN 2405-8440
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
DOI 10.1016/j.heliyon.2020.e05743
Related Url isVersionOf https://doi.org/10.1016/j.heliyon.2020.e05743
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Author Tan, Xian Wen| Takenaka, Fumiaki| Takekawa, Hironori| Matsuura, Eiji|
Keywords Biological sciences Antibody Biochemistry Lipid peroxidation Health sciences Oxidized LDL (oxLDL) β2-glycoprotein I (β2GPI) OxLDL-β2GPI Lateral flow immunoassay (LFIA) Enzyme-linked immunosorbent assay (ELISA) Point-of-care
Published Date 2020-06-08
Publication Title Heliyon
Volume volume6
Issue issue6
Publisher Elsevier
Start Page e04114
ISSN 2405-8440
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors
File Version publisher
PubMed ID 32551380
DOI 10.1016/j.heliyon.2020.e04114
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Author Shen, Lianhua| Yamamoto, Takushi| Tan, Xian Wen| Ogata, Koretsugu| Ando, Eiji| Ozeki, Eiichi| Matsuura, Eiji|
Keywords Atherosclerosis Low-density lipoprotein (LDL) Oxidized LDL (oxLDL) Oxidized lipids; Imaging mass microscopy (iMScope) Mass spectroscopy (MS)
Published Date 2020-08-28
Publication Title Atherosclerosis
Volume volume311
Publisher Elsevier
Start Page 1
End Page 12
ISSN 00219150
NCID AA00553457
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 32911376
DOI 10.1016/j.atherosclerosis.2020.08.001
Related Url isVersionOf https://doi.org/10.1016/j.atherosclerosis.2020.08.001
JaLCDOI 10.18926/AMO/53999
FullText URL 70_1_13.pdf
Author Arum Tri Wahyuningsih| Shen, Lianhua| Kobayashi, Kazuko| Sasaki, Takanori| Takenaka, Fumiaki| Hanada, Takahisa| Akehi, Masaru| Akahoshi, Akiya| Ozeki, Eiichi| Ando, Eiji| Matsuura, Eiji|
Abstract Intact β2-glycoprotein I (iβ2GPI) is a glycoprotein that regulates coagulation and fibrinolysis. Nicked β2GPI (nβ2GPI) possesses an angiogenic property at a relatively low concentration, and an antiangiogenic property at a high concentration. Here we investigated the functions of βi 2GPI and nβ2GPI in vascular endothelial growth factor (VEGF)-A-induced endothelial cell proliferation and tube formation. We used noninvasive PET imaging to analyze the in vivo distribution of intravenously injected β2GPI variants in tumor lesions in mice. iβ2GPI was incubated with plasmin to obtain nβ2GPI, and its N-terminal sequence was analyzed. nβ2GPI had at least one other cleavage site upstream of the β2GPIʼs domain V, whereas the former plasmin-cleavage site locates between K317 and T318. Both of intact and nicked β2GPI significantly inhibited the VEGF-A-induced cell proliferation and the tube formation of human umbilical vein endothelial cells (HUVECs). PET imaging visualized considerably distributed intensities of all tested β2GPI variants in tumor lesions of pancreatic tumor cell-xenografts. These results indicate that β2GPI may be physiologically and pathophysiologically important in the regulation of not only coagulation and fibrinolysis, but also angiogenesis.
Keywords β2-glycoprotein I (β2GPI) angiogenesis vascular endothelial growth factor-A (VEGF-A) positron emission tomography (PET) imaging
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2016-02
Volume volume70
Issue issue1
Publisher Okayama University Medical School
Start Page 13
End Page 24
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 26899605
Web of Science KeyUT 000371288700002
Author Matsuura, Eiji|
Published Date 2013-04-01
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue1
Content Type Journal Article
Author Matsuura, Eiji| Igarashi, Yoshiko| Yasuda, Tatsuji| Triplett, Douglas A.| Koike, Takao|
Published Date 1994-02-01
Publication Title Journal of Experimental Medicine
Volume volume179
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/AMO/32848
FullText URL fulltext.pdf
Author Huang, Zhenyu| Liu, Qingping| Li, Wenzhe| Wang, Renjun| Wang, Dan| Zhang, Yingbiao| Zhang, Fan| Chi, Yan| Liu, Zhe| Matsuura, Eiji| Liu, Zibo| Zhang, Qiming|
Abstract

We investigated the molecular mechanisms responsible for the induction of apoptosis in mouse monocytic macrophage cell line J774A.1 stimulated by 7-ketocholesterol (7-KC). Cell apoptosis was detected by Annexin V-propidium iodide (PI) staining. The DNA-binding activity of nuclear factor kappa B (NF-kappaB) was assessed by electrophoretic mobility shift assay (EMSA). Results showed that 7-KC-stimulation in J774A.1 cells activated NF-kappaB, which is involved in cell apoptosis, in a time- and dose-dependent manners. 7-KC was also found to increase the binding activity of NF-kappaB to specific DNA binding sites, a possible mechanism for the induction of the cell apoptosis. Moreover, these effects were partially inhibited by pyrrolidine dithiocarbamate (PDTC), an NF-kappaB inhibitor. Taken together, 7-KC may be an important factor in atherosclerosis due to the ability of 7-KC to induce cell apoptosis, which is at least partially mediated through the activation of NF-kappaB.

Keywords 7-KC NF-?B apoptosis atherosclerosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-04
Volume volume64
Issue issue2
Publisher Okayama University Medical School
Start Page 85
End Page 93
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 20424663
Web of Science KeyUT 000276996900002
Author 松浦 栄次|
Published Date 2002-05-30
Publication Title 岡山医学会雑誌
Volume volume114
Issue issue1
Content Type Journal Article
Author Matsuura, Eiji|
Published Date 1994-03-25
Publication Title
Content Type Thesis or Dissertation