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Eto, Eriko Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ORCID Kaken ID researchmap
Kato, Masakazu Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kirino, Satoe
Kuriyama, Chiaki Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Sakata, Syujiro Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Nakato, Hikari Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Mishima, Sakurako Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Ohira, Akiko Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Masuyama, Hisashi Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID publons researchmap
Abstract
Aims/Introduction: Maternal hyperglycemia is associated with heavy for date (HFD) infants. Considering the association between body composition and hyperglycemia, we investigated the changes in maternal body composition and their relationship with HFD infants in pregnant women with diabetes.
Materials and Methods: Body composition was measured during pregnancy using a bioelectrical impedance analysis system. This retrospective study included 151 pregnant women; 27 women had type 1 diabetes mellitus (DM), 21 had type 2 DM, 101 were diagnosed with gestational DM, and 2 had overt DM. The number of HFD infants was 40.
Results: In the non-type 1 DM group, change in fat mass (ΔFM) (P < 0.01) and pre-pregnancy BMI (P < 0.05) were risk factors for HFD. In the insulin group, ΔFM, pre-pregnancy BMI, and age (all P < 0.05) were risk factors for HFD. The area under the curve was 0.813 for the predictive model combined with ΔFM and pre-pregnancy BMI in the non-type 1 DM group and 0.818 for the model combined with ΔFM, pre-pregnancy BMI, and age in the insulin group.
Conclusions: The combination of body composition parameters and clinical data may predict HFD in pregnant women with diabetes.
Keywords
Fat mass gain
Heavy for date
Maternal body composition
Published Date
2025-07-26
Publication Title
Journal of Diabetes Investigation
Publisher
Wiley
ISSN
2040-1116
NCID
AA12488319
Content Type
Journal Article
language
English
OAI-PMH Set
岡山大学
Copyright Holders
© 2025 The Author(s).
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isVersionOf https://doi.org/10.1111/jdi.70131
License
http://creativecommons.org/licenses/by-nc/4.0/
Citation
Eto, E., Kato, M., Kirino, S., Kuriyama, C., Sakata, S., Nakato, H., Mishima, S., Ohira, A. and Masuyama, H. (2025), Relationship between maternal body composition changes and heavy for date infants in pregnant women with diabetes. J Diabetes Investig. https://doi.org/10.1111/jdi.70131