ID | 31293 |
JaLCDOI | |
FullText URL | |
Author |
Hashimoto, Kozo
Ohno, Norihito
Aoki, Yoshiyuki
Kageyama, Jingo
Kaken ID
researchmap
Takahara, Jiro
Ofuji, Tadashi
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Abstract | The distribution of corticotropin releasing factor (CRF) and arginine vasopressin (AVP) in hypothalamic nuclei were examined in control and estrogen-treated female rats. CRF activity was measured using monolayer cultured rat anterior pituitary cells and AVP by radioimmunoassay. Hypothalamic nuclei were punched out according to the method of Palkovits. The distribution of CRF activity in 5 different hypothalamic nuclei was similar to that of AVP in intact female rats. CRF activity in hypothalamic nuclei, pituitary ACTH content and plasma ACTH levels in estrogen-treated rats were not significantly different from those in control rats. However, significant elevation of AVP content was observed in the supraoptic and paraventricular nuclei of estrogen-treated rats. These results indicate that CRF and AVP are distributed in similar hypothalamic nuclei, but that they are not identical. |
Keywords | corticotropin releasing factor (CRF)
arginine vasopressin (AVP)
hypothalamic nucler.
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Amo Type | Article
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Publication Title |
Acta Medica Okayama
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Published Date | 1981-02
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Volume | volume35
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Issue | issue1
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Publisher | Okayama University Medical School
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Start Page | 37
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End Page | 43
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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File Version | publisher
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Refereed |
True
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PubMed ID | |
Web of Science KeyUT |