ID | 57806 |
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Author |
Sugimoto, Seiichiro
Department of General Thoracic SurgeryOkayama University Hospital
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Kurosaki, Takeshi
Department of Organ Transplant CenterOkayama University Hospital
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Otani, Shinji
Department of Organ Transplant CenterOkayama University Hospital
Tanaka, Shin
Department of General Thoracic SurgeryOkayama University Hospital
Hikasa, Yukiko
Department of Anesthesiology and ResuscitologyOkayama University Hospital
Yamane, Masaomi
Department of General Thoracic SurgeryOkayama University Hospital
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Toyooka, Shinichi
Department of General Thoracic SurgeryOkayama University Hospital
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Abstract | PURPOSE:
When patients are mechanically ventilated for more than 5 days, they are usually declined as donors for lung transplantation (LTx); thus, the long-term outcomes of LTx from such donors remain unclear. We investigated the feasibility of LTx from donors that had been mechanically ventilated for prolonged periods. METHODS: The subjects of this retrospective comparative investigation were 31 recipients of LTx from donors who had been mechanically ventilated for < 5 days (short-term group) and 50 recipients of LTx from donors who had been mechanically ventilated for ≥ 5 days (long-term group). RESULTS: The median duration of donor mechanical ventilation was 3 days in the short-term group and 8.5 days in the long-term group. However, other than the difference in the duration of donor ventilation, there were no significant differences in the clinical characteristics of the donors or recipients between the groups. The overall survival rate after LTx was comparable between the long-term group and short-term group (5-year survival rate, 66.6% vs. 75.2%). CONCLUSION: The potential inclusion of donors who have been on mechanical ventilation for more than 5 days could be a feasible strategy to alleviate donor organ shortage. |
Keywords | Brain-dead donor
Extended-criteria donor
Lung transplantation
Marginal donor
Mechanical ventilation
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Published Date | 2018-10-27
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Publication Title |
Surgery Today
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Volume | volume49
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Issue | issue3
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Publisher | Springer
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Start Page | 254
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End Page | 260
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ISSN | 0941-1291
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NCID | AA10824685
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Content Type |
Journal Article
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language |
English
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OAI-PMH Set |
岡山大学
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File Version | author
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Related Url | isVersionOf https://doi.org/10.1007/s00595-018-1730-z
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License | https://creativecommons.org/licenses/by-nc-nd/4.0/
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