JaLCDOI 10.18926/AMO/30377
FullText URL fulltext.pdf
Author Furuno, Katsushi| Okazaki, Masatoshi| Eto, Kohei| Kawasaki, Hiromu| Gomita, Yutaka|
Abstract <p>The effects of acute exposure to cigarette smoke and systemic administration of nicotine on intestinal propulsion were investigated in rats. The propulsive activity was measured as migration of charcoal powder in the intestine. This activity was suppressed by acute exposure (10 min) to cigarette smoke and by nicotine (0.5 mg/kg x 2, s.c.) administration. This intestinal suppression was more marked in the rats given nicotine than in those exposed to cigarette smoke, whereas the plasma concentrations of nicotine in both rats were similar. These results suggest that acute exposure to cigarette smoke and nicotine administration delay gastric emptying and/or suppress intestinal propulsion, and that some components other than nicotine contained in cigarette smoke may attenuate the suppression of intestinal propulsion induced by nicotine.</p>
Keywords cigarette smoke nicotine intestinal propulsion
Amo Type Article
Published Date 1995-08
Publication Title Acta Medica Okayama
Volume volume49
Issue issue4
Publisher Okayama University Medical School
Start Page 201
End Page 204
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7502680
Web of Science KeyUT A1995RR97800004
Author Takatori, Shingo| Kawasaki, Hiromu| Mio, Mitsunobu|
Published Date 2006-12
Publication Title 岡山実験動物研究会報
Volume volume23
Content Type Journal Article