FullText URL fulltext.pdf
Author Inai, Ryota| Nakahara, Ryuichi| Morimitsu, Yusuke| Akagi, Noriaki| Marukawa, Youhei| Matsushita, Toshi| Tanaka, Takashi| Tada, Akihiro| Hiraki, Takao| Nasu, Yoshihisa| Nishida, Keiichiro| Ozaki, Toshifumi| Kanazawa, Susumu|
Keywords Osteoporosis Bone density Tomography (x-ray computed) X-ray microtomography
Published Date 2021-01-28
Publication Title European Radiology Experimental
Volume volume4
Issue issue1
Publisher Springer nature
Start Page 4
ISSN 2509-9280
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2020
File Version publisher
PubMed ID 31993864
DOI 10.1186/s41747-019-0135-0
Web of Science KeyUT 000705622700001
Related Url isVersionOf https://doi.org/10.1186/s41747-019-0135-0
Author Shirakawa, Yasuhiro| Tazawa, Hiroshi| Tanabe, Shunsuke| Kanaya, Nobuhiko| Noma, Kazuhiro| Koujima, Takeshi| Kashima, Hajime| Kato, Takuya| Kuroda, Shinji| Kikuchi, Satoru| Kagawa, Shunsuke| Katsui, Kuniaki| Kanazawa, Susumu| Urata, Yasuo| Fujiwara, Toshiyoshi|
Keywords Telomerase adenovirus radiotherapy esophageal cancer immunotherapy
Note This is an Accepted Manuscript of an article published by Elsevier.<br> This fulltext is available in July 2022.|
Published Date 2021-8
Publication Title European Journal of Cancer
Volume volume153
Publisher Elsevier BV
Start Page 98
End Page 108
ISSN 0959-8049
NCID AA1075407X
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Elsevier Ltd.
File Version author
PubMed ID 34153720
DOI 10.1016/j.ejca.2021.04.043
Web of Science KeyUT 000686051300013
Related Url isVersionOf https://doi.org/10.1016/j.ejca.2021.04.043
FullText URL fulltext20210824-1.pdf
Author Tekiki, Nouha| Kuroda, Masahiro| Ishizaka, Hinata| Khasawneh, Abdullah| Barham, Majd| Hamada, Kentaro| Konishi, Kohei| Sugimoto, Kohei| Katsui, Kuniaki| Sugiyama, Soichi| Watanabe, Kenta| Yoshio, Kotaro| Katayama, Norihisa| Ogata, Takeshi| Ihara, Hiroki| Kanazawa, Susumu| Asaumi, Junichi|
Keywords breast cancer field‑in‑field radiotherapy dose reference point acute skin toxicity dose distribution high‑dose area
Note This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License.|
Published Date 2021-7-21
Publication Title Molecular and Clinical Oncology
Volume volume15
Issue issue3
Publisher Spandidos Publications
ISSN 2049-9450
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © Tekiki et al.
File Version publisher
PubMed ID 34349992
DOI 10.3892/mco.2021.2355
Web of Science KeyUT 000680476900001
Related Url isVersionOf https://doi.org/10.3892/mco.2021.2355
FullText URL fulltext.pdf
Author Katsui, Kuniaki| Ogata, Takeshi| Sugiyama, Soichi| Yoshio, Kotaro| Kuroda, Masahiro| Hiraki, Takao| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
Published Date 2021-06-04
Publication Title scientific reports
Volume volume11
Issue issue1
Publisher Nature Research
Start Page 11882
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 34088965
DOI 10.1038/s41598-021-91449-z
Web of Science KeyUT 000678611200010
Related Url isVersionOf https://doi.org/10.1038/s41598-021-91449-z
Author Tanaka, Takashi| Kawashima, Akira| Marukawa, Yohei| Kitayama, Takahiro| Masaoka, Yoshihisa| Kojima, Katsuhide| Iguchi, Toshihiro| Hiraki, Takao| Kanazawa, Susumu|
Keywords Hereditary renal tumor syndrome Von Hippel–Lindau disease Birt–Hogg–Dubé syndrome Tuberous sclerosis complex Hereditary leiomyomatosis and renal cell carcinoma syndrome
Note This fulltext is available in Mar 2022| This is an Accepted Manuscript of an article published by Springer|
Published Date 2021-3-23
Publication Title Japanese Journal of Radiology
Publisher Springer Science and Business Media LLC
ISSN 1867-1071
NCID AA12375935
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 33759057
NAID 130008000092
DOI 10.1007/s11604-021-01109-5
Web of Science KeyUT 000631734600001
Related Url isVersionOf https://doi.org/10.1007/s11604-021-01109-5
FullText URL fulltext.pdf
Author Watanabe, Kenta| Katsui, Kuniaki| Sugiyama, Soichiro| Yoshio, Kotaro| Kuroda, Masahiro| Hiraki, Takao| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
Keywords Clinical pathology Elderly Non-small cell lung carcinoma Radiosurgery Stereotactic body radiation therapy
Published Date 2021-02-23
Publication Title Radiation Oncology
Volume volume16
Issue issue1
Publisher BMC
Start Page 39
ISSN 1748-717X
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021.
File Version publisher
PubMed ID 33622369
DOI 10.1186/s13014-021-01769-7
Web of Science KeyUT 000623175000001
Related Url isVersionOf https://doi.org/10.1186/s13014-021-01769-7
JaLCDOI 10.18926/AMO/61438
FullText URL 75_1_79.pdf
Author Yoshio, Kotaro| Nagasaka, Hisako| Hisazumi, Kento| Okawa, Hiro| Tajiri, Nobuhisa| Shiode, Tsuyoki| Akaki, Shiro| Kanazawa, Susumu| Mitoma, Tomohiro| Yano, Yuri| Kobayashi, Emiko| Horiguchi, Ikuyo| Takata, Masayo| Hongo, Atsushi| Yonezawa, Masaru| Nakanishi, Yoshie|
Abstract The purposes of this retrospective study were to analyze local control of squamous cell carcinoma of the cervix treated with computed tomography (CT)-based image-guided brachytherapy (IGBT), as well as the factors affecting local control. A total of 39 patients were analyzed. The prescribed dose to the pelvis was 45-50 Gy with or without central shielding (CS). IGBT was delivered in 1-5 fractions. The total dose for high-risk clinical target volume (HR-CTV) was calculated as the biologically equivalent dose in 2-Gy fractions. The median follow-up period was 29.3 months. The 2-year overall survival and local control rates were 97% and 91%, respectively. In univariate analysis, the dose covering 90% of the HR-CTV (D90) and tumor size were found to be significant factors for local control. The cutoff values of tumor size and D90 for local control were 4.3 cm (area under the curve [AUC] 0.75) and 67.7 Gy (AUC 0.84) in the CS group and 5.3 cm (AUC 0.75) and 73.7 Gy (AUC 0.78) in the group without CS, respectively. However, though the local control of CT-based IGBT was favorable, the results suggested that the dose required for tumor control may differ depending on the presence of CS.
Keywords cervical cancer squamous cell cancer brachytherapy central shielding
Amo Type Original Article
Published Date 2021-02
Publication Title Acta Medica Okayama
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 79
End Page 85
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649617
JaLCDOI 10.18926/AMO/61429
FullText URL 75_1_15.pdf
Author Katsui, Kuniaki| Ogata, Takeshi| Tada, Akihiro| Sugiyama, Soichi| Yoshio, Kotaro| Kuroda, Masahiro| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Hiraki, Takao| Kanazawa, Susumu|
Abstract The aim of this study was to investigate whether volumetric positron emission tomography (PET) parameters are prognostic predictors in stage III non-small cell lung cancer patients receiving definitive concurrent chemo-radiotherapy (CCRT) with cisplatin/docetaxel. Cases involving definitive CCRT were reviewed retrospectively, and the maximum standardized uptake value, metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were calculated. The relationships between these PET parameters and prognosis were analyzed. MTV and TLG were significant predictors of distant metastasis-free survival (DMFS) (p = 0.0003 and 0.0005, respectively) and progression-free survival (PFS) (p = 0.001 and 0.0007, respectively). The three-year DMFS rates in patients with low and high MTV were 13.3% and 64.6%, respectively, and the corresponding values in those with low and high TLG were 13.3% and 65.2%, respectively. The three-year PFS rates in patients with low and high MTV were 13.3% and 57.8%, respectively, and the corresponding values in patients with low and high TLG were 13.3% and 57.8%, respectively. However, MTV and TLG were not predictors of local control or overall sur-vival. We demonstrated that volumetric PET parameters were predictors of patients receiving definitive CCRT. Our findings contradict the findings of previous reports and warrant further research to validate them.
Keywords volumetric positron emission tomography parameters distant metastasis-free survival chemoradiotherapy cisplatin/docetaxel non-small cell lung cancer
Amo Type Original Article
Published Date 2021-02
Publication Title Acta Medica Okayama
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 15
End Page 23
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649609
JaLCDOI 10.18926/AMO/61428
FullText URL 75_1_9.pdf
Author Gobara, Hideo| Yamamoto, Akira| Komakic, Toshiyuki| Kitayama, Toshiaki| Sakurai, Jun| Iguchi, Toshihiro| Matsui, Yusuke| Uka, Mayu| Tomita, Koji| Hiraki, Takao| Kanazawa, Susumu|
Abstract To assess the feasibility of needle tract ablation in liver tissue in ex vivo and in vivo animal models using a cryo-probe and electrosurgical device. The experimental device is made by inserting a cryoprobe through an intro-ducer sheath for insulation, with 2-cm of probe tip projecting out. A beagle liver was punctured by the device, and electric current was applied at 30-W with the electrosurgical knife touching the non-insulated device base. The discolored area of cut surface along the device was evaluated in 5 application-time groups (5 , 10 , 15 , 20, or 25 seconds). An ex vivo experiment was performed to determine an ablation algorithm with an appropriate application time by comparison with radiofrequency ablation (RFA) results. Thereafter, an in vivo experiment was performed to verify the algorithm’s feasibility. In the ex vivo model, the cut surface demonstrated different amounts of discolored area according to the application time. The total discolored area in the 20-seconds group was similar to that by RFA. In the in vivo model, the liver did not bleed, the total discolored area was similar to that ex vivo, and coagulation necrosis was confirmed by photomicrograph. Needle tract ablation can be per-formed using the experimental device and electrosurgical device.
Keywords needle tract ablation cryoablation electrosurgical device animal liver
Amo Type Original Article
Published Date 2021-02
Publication Title Acta Medica Okayama
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 9
End Page 14
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649608
FullText URL fulltext.pdf
Author Komaki, Toshiyuki| Hiraki, Takao| Kamegawa, Tetsushi| Matsuno, Takayuki| Sakurai, Jun| Matsuura, Ryutaro| Yamaguchi, Takuya| Sasaki, Takanori| Mitsuhashi, Toshiharu| Okamoto, Soichiro| Uka, Mayu| Matsui, Yusuke| Iguchi, Toshihiro| Gobara, Hideo| Kanazawa, Susumu|
Keywords Robotics Interventional radiology Animal experiments
Published Date 2019-11-26
Publication Title European Radiology
Volume volume30
Issue issue3
Publisher Springer
Start Page 1342
End Page 1349
ISSN 0938-7994
NCID AA10824302
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © Authors
File Version publisher
PubMed ID 31773299
DOI 10.1007/s00330-019-06477-1
Web of Science KeyUT 000517458800006
Related Url isVersionOf https://doi.org/10.1007/s00330-019-06477-1
JaLCDOI 10.18926/AMO/60806
FullText URL 74_5_443.pdf
Author Sekito, Takanori| Araki, Motoo| Hiraki, Takao| Uka, Mayu| Komaki, Toshiyuki| Matsui, Yusuke| Iguchi, Toshihiro| Katayama, Satoshi| Yoshinaga, Kasumi| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Kubota, Risa| Sadahira, Takuya| Nishimura, Shingo| Wada, Koichiro| Takamoto, Atsushi| Edamura, Kohei| Sako, Tomoko| Kobayashi, Yasuyuki| Watanabe, Toyohiko| Kanazawa, Susumu| Nasu, Yasutomo|
Abstract We report a 47-year-old Japanese female with 10 previous treatments for multiple bilateral renal cell carcinoma (RCC) associated with von Hippel-Lindau disease. The 14-mm right lower pole renal tumor was in contact with the right ureter. Laparoscopic cryoablation was performed to protect the ureter wrapped with gauze. Computed tomography (CT) monitoring was used to confirm the precise ≥ 6 mm ice-ball margin. There was no local progression at 6-months post-surgery. The serum creatinine has been stable. This is apparently the first report of combined laparoscopic and CT monitoring of an ice-ball formation and its margin during cryoablation for RCC.
Keywords laparoscopic cryoablation multiple renal masses nephron-sparing surgery renal cell carcinoma von Hippel-Lindau disease
Amo Type Case Report
Note Fig. 1B is replaced on Dec. 23, 2020.|
Published Date 2020-10
Publication Title Acta Medica Okayama
Volume volume74
Issue issue5
Publisher Okayama University Medical School
Start Page 443
End Page 448
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33106702
Web of Science KeyUT 000581970100011
NAID 120006892932
FullText URL fulltext.pdf
Author Katayama, Norihisa| Katsui, Kuniaki| Watanabe, Kenta| Nagao, Ryota| Otsuki, Kaho| Hiraki, Takao| Kanazawa, Susumu|
Keywords Bone metastasis breast cancer (BCa) oligometastatic radiation therapy (RT) stereotactic body radiation therapy (SBRT)
Published Date 2020-08
Publication Title Translational Cancer Research
Volume volume9
Issue issue8
Publisher AME Publoshing Company
Start Page 5096
End Page 5101
ISSN 2218-676X
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © Translational Cancer Research. All rights reserved.
File Version publisher
DOI 10.21037/tcr.2020.01.35
Web of Science KeyUT 000562138400066
Related Url isVersionOf https://doi.org/10.21037/tcr.2020.01.35
FullText URL fulltext.pdf
Author Sugimoto, Seiichiro| Soh, Junichi| Suzawa, Ken| Miyoshi, Kentaroh| Otani, Shinji| Yamamoto, Hiromasa| Okazaki, Mikio| Yamane, Masaomi| Oto, Takahiro| Kanazawa, Susumu| Kiura, Katsuyuki| Toyooka, Shinichi|
Keywords Lung cancer Aspergillosis Surgery Radiation Chemotherapy
Note This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-020-01960-5.|
Published Date 2020-01-21
Publication Title Surgery Today
Volume volume50
Issue issue8
Publisher Springer
Start Page 863
End Page 871
ISSN 0941-1291
NCID AA10824685
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 31965262
DOI 10.1007/s00595-020-01960-5
Web of Science KeyUT 000550244700010
Related Url isVersionOf https://doi.org/10.1007/s00595-020-01960-5
JaLCDOI 10.18926/AMO/59951
FullText URL 74_3_209.pdf
Author Matsui, Yusuke| Hiraki, Takao| Iguchi, Toshihiro| Sakurai, Jun| Uka, Mayu| Masaoka, Yoshihisa| Gobara, Hideo| Kanazawa, Susumu|
Abstract An aspiration-type semi-automatic cutting biopsy needle enables tissue cutting during application of negative pressure, which is expected to contribute to a larger amount of specimen. The aim of the present study was to evaluate this novel needle in a clinical setting. Patients who underwent image-guided percutaneous biopsy for lung or renal masses were enrolled. Cutting biopsy was performed with and without aspiration during each procedure. The specimens were weighed using an electronic scale. The weights were compared between specimens obtained with and without aspiration using a paired t-test. The data from 45 lung and 30 renal biopsy procedures were analyzed. In lung biopsy, the mean±standard deviation weights of specimens obtained with and without aspiration were 2.20±1.05 mg and 2.24±1.08 mg, respectively. In renal biopsy, the mean weights were 6.52±2.18 mg and 6.42±1.62 mg, respectively. The weights were not significantly different between specimens obtained with and without aspiration either in lung (p=0.799) or renal (p=0.789) biopsies. The application of negative pressure with the aspiration-type semi-automatic cutting biopsy needle did not contribute to an increase in the amount of the specimen obtained in lung and renal biopsies.
Keywords biopsy cutting needle aspiration clinical study
Amo Type Original Article
Published Date 2020-06
Publication Title Acta Medica Okayama
Volume volume74
Issue issue3
Publisher Okayama University Medical School
Start Page 209
End Page 214
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32577018
Web of Science KeyUT 000543363400004
NAID 120006862793
FullText URL fulltext.pdf
Author Nakayama, Rie| Takaya, Yoichi| Akagi, Teiji| Nakagawa, Koji| Watanabe, Nobuhisa| Nobusada, Saori| Matsushita, Toshi| Toh, Norihisa| Kanazawa, Susumu| Ito, Hiroshi|
Published Date 2020-04-28
Publication Title Journal of Interventional Cardiology
Volume volume2020
Publisher Hindawi
Start Page 9509105
ISSN 0896-4327
NCID AA10705096
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Rie Nakayama et al.
File Version publisher
PubMed ID 32410917
DOI 10.1155/2020/9509105
Web of Science KeyUT 000533371500001
Related Url isVersionOf https://doi.org/10.1155/2020/9509105
FullText URL fulltext.pdf
Author Katsui, Kuniaki| Ogata, Takeshi| Watanabe, Kenta| Katayama, Norihisa| Kuroda, Masahiro| Kiura, Katsuyuki| Hiraki, Takao| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
Keywords cisplatin docetaxel dose-volume histogram non-small cell lung cancer PACIFIC trial radiation pneumonitis
Published Date 2020-05-04
Publication Title Cancer Medicine
Publisher Wiley
ISSN 2045-7634
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 32364685
DOI 10.1002/cam4.3093
Web of Science KeyUT 000530411600001
Related Url isVersionOf https://doi.org/10.1002/cam4.3093
FullText URL fulltext.pdf
Author Katayama, Norihisa| Sato, Shuhei| Katsui, Kuniaki| Takemoto, Mitsuhiro| Tsuda, Toshihide| Yoshida, Atsushi| Morito, Tsuneharu| Nakagawa, Tomio| Mizutani, Akifumi| Waki, Takahiro| Niiya, Harutaka| Kanazawa, Susumu|
Keywords Breast cancer Breast-conserving surgery Radiotherapy Radiation-induced BOOP syndrome Endocrine therapy
Published Date 2009-03-15
Publication Title International journal of radiation oncology, biology, physics
Volume volume73
Issue issue4
Publisher Elsevier
Start Page 1049
End Page 1054
ISSN 0360-3016
NCID AA00680920
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 18755559
DOI 10.1016/j.ijrobp.2008.05.050
Web of Science KeyUT 000264257400014
Related Url isVersionOf https://doi.org/10.1016/j.ijrobp.2008.05.050
JaLCDOI 10.18926/AMO/58271
FullText URL 74_2_129.pdf
Author Fukuma, Shogo| Shinya, Takayoshi| Soh, Junichi| Fukuhara, Ryuichiro| Ogawa, Nanako| Higaki, Fumiyo| Tanaka, Takehiro| Ichihara, Eiki| Hiraki, Takao| Toyooka, Shinichi| Kanazawa, Susumu|
Abstract The aim of this study was to explore enhancement patterns of different types of primary lung cancers on 2-phase dynamic computed tomography (CT). This study included 217 primary lung cancer patients (141 adenocarcinomas [ADs], 48 squamous cell carcinomas [SCCs], 20 small cell lung carcinomas [SCLCs], and 8 others) who were examined using a 2-phase dynamic scan. Regions of interest were identified and mean enhancement values were calculated. After excluding the 20 SCLCs because these lesions had different clinical stages from the other cancer types, the mean attenuation values and subtractions between phases were compared between types of non-small cell lung carcinomas (NSCLCs) using the Kruskal–Wallis test. Late phase attenuation and attenuation of the late minus unenhanced phase (LMU) of SCCs were significantly higher than those of ADs (p<0.05). To differentiate SCC and AD in the late phase, a threshold of 80.21 Hounsfield units (HU) gave 52.9% accuracy. In LMU, a threshold of 52.16 HU gave 59.3% accuracy. Dynamic lung CT has the potential to aid in differentiating among NSCLC types.
Keywords differentiation dynamic computed tomography primary lung cancer enhancement pattern
Amo Type Original Article
Published Date 2020-04
Publication Title Acta Medica Okayama
Volume volume74
Issue issue2
Publisher Okayama University Medical School
Start Page 129
End Page 135
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32341587
Web of Science KeyUT 000528278500006
NAID 120006839450
JaLCDOI 10.18926/AMO/58270
FullText URL 74_2_123.pdf
Author Fukuhara, Ryuichiro| Shinya, Takayoshi| Fukuma, Shogo| Ogawa, Nanako| Masaoka, Yoshihisa| Tanaka, Takehiro| Marunaka, Hidenori| Arioka, Tadashi| Hiraki, Takao| Kaji, Mitsumasa| Kanazawa, Susumu|
Abstract The aim of this study was to evaluate the ability of pretreatment 90-min 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to predict the extranodular spread of lymph node metastases in oral squamous cell carcinoma. We retrospectively reviewed the cases of 56 patients who underwent pretreatment 18F-FDG PET/CT and surgery with neck dissection. Maximum standardized uptake value, metabolic tumor volume, and total lesion glycolysis were measured for the 56 primary sites and maximum standardized uptake value was measured for 115 lymph node levels. Extranodular spread was present at 9 lymph node levels in 7 patients. Significant differences were found in metabolic tumor volume and total lesion glycolysis of the primary site, and in lymph node maximum standardized uptake value, between patients with and without extranodular spread (p<0.05). Combining primary site total lesion glycolysis and lymph node maximum standardized uptake volume at their respective optimal cutoffs, the sensitivity, specificity, and accuracy for predicting extranodular spread were 89%, 92%, and 92%, respectively. Pretreatment 18F-FDG PET/CT is useful for predicting extranodular spread in patients with oral squamous cell carcinoma. The combined use of primary site total lesion glycolysis and lymph node maximum standardized uptake value showed greater predictive value than either predictor singly.
Keywords 18F-fluorodeoxyglucose positron emission tomography/computed tomography extranodular spread metastasis oral squamous cell carcinoma
Amo Type Original Article
Published Date 2020-04
Publication Title Acta Medica Okayama
Volume volume74
Issue issue2
Publisher Okayama University Medical School
Start Page 123
End Page 128
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32341586
Web of Science KeyUT 000528278500005
NAID 120006839449
FullText URL fulltext.pdf
Author Matsubara, Takehiro| Soh, Junichi| Morita, Mizuki| Uwabo, Takahiro| Tomida, Shuta| Fujiwara, Toshiyoshi| Kanazawa, Susumu| Toyooka, Shinichi| Hirasawa, Akira|
Published Date 2020-02-27
Publication Title BioMed Research International
Volume volume2020
Publisher Hindawi
Start Page 9349132
ISSN 2314-6133
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Takehiro Matsubara et al.
File Version publisher
PubMed ID 32185225
DOI 10.1155/2020/9349132
Web of Science KeyUT 000522222100002
Related Url isVersionOf https://doi.org/10.1155/2020/9349132