| FullText URL | fulltext.pdf suppl.docx |
|---|---|
| Author | Tsuboi, Ichiro| Kardoust Parizi, Mehdi| Matsukawa, Akihiro| Miszczyk, Marcin| Fazekas, Tamás| Cormio, Angelo| Kawada, Tatsushi| Katayama, Satoshi| Iwata, Takehiro| Bekku, Kensuke| Wada, Koichiro| Karakiewicz, Pierre I.| Chlosta, Piotr| Briganti, Alberto| Araki, Motoo| Shariat, Shahrokh F.| |
| Keywords | Febrile urinary tract infection Targeted prophylactic antibiotics Transrectal prostate biopsy Sepsis |
| Published Date | 2025-10 |
| Publication Title | European Urology Open Science |
| Volume | volume80 |
| Publisher | Elsevier BV |
| Start Page | 57 |
| End Page | 65 |
| ISSN | 2666-1683 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| PubMed ID | 41064532 |
| DOI | 10.1016/j.euros.2025.08.007 |
| Web of Science KeyUT | 001572715700001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.euros.2025.08.007 |
| FullText URL | fulltext.pdf suppl1.tif suppl2.tif suppl3.tif |
|---|---|
| Author | Tominaga, Yusuke| Kobayashi, Tomoko| Matsumoto, Yuko| Sako, Tomoko| Moriwake, Takatoshi| Horii, Satoshi| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Bekku, Kensuke| Edamura, Kohei| Watanabe, Masami| Araki, Motoo| |
| Keywords | Finasteride Dihydrotestosterone Transgender men Androgenetic alopecia Resumption of menstruation |
| Published Date | 2025-09-29 |
| Publication Title | Journal of Medical Case Reports |
| Volume | volume19 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 468 |
| ISSN | 1752-1947 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025. |
| File Version | publisher |
| PubMed ID | 41024043 |
| DOI | 10.1186/s13256-025-05562-y |
| Web of Science KeyUT | 001585008600008 |
| Related Url | isVersionOf https://doi.org/10.1186/s13256-025-05562-y |
| FullText URL | fulltext.pdf suppl.pdf |
|---|---|
| Author | Nishimura, Shingo| Inoue, Shota| Sekito, Takanori| Tsuboi, Ichiro| Tokunaga, Moto| Yoshinaga, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Yamanoi, Tomoaki| Kawada, Tatsushi| Kubota, Risa| Sadahira, Takuya| Tominaga, Yusuke| Iwata, Takehiro| Katayama, Satoshi| Bekku, Kensuke| Edamura, Kohei| Wada, Koichiro| Kobayashi, Yasuyuki| Araki, Motoo| |
| Keywords | living donor kidney transplantation urinary tract infection perioperative desensitization rituximab plasmapheresis body mass index dialysis duration warm ischemic time prophylactic antimicrobials |
| Published Date | 2025-08-28 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume14 |
| Issue | issue17 |
| Publisher | MDPI AG |
| Start Page | 6102 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 by the authors. |
| File Version | publisher |
| PubMed ID | 40943861 |
| DOI | 10.3390/jcm14176102 |
| Web of Science KeyUT | 001571365300001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm14176102 |
| FullText URL | fulltext.pdf suppl.docx |
|---|---|
| Author | Kubota, Risa| Sada, Ken-Ei| Tokunaga, Moto| Yoshinaga, Kasumi| Yamanoi, Tomoaki| Kawada, Tatsushi| Tominaga, Yusuke| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Bekku, Kensuke| Edamura, Kohei| Kobayashi, Tomoko| Nakagawa, Yuki| Ichimaru, Naotsugu| Wada, Koichiro| Araki, Motoo| |
| Keywords | Calcineurin inhibitors Cyclosporine A Kidney transplant Malignant neoplasms Tacrolimus |
| Published Date | 2025-08-26 |
| Publication Title | BMC Nephrology |
| Volume | volume26 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 491 |
| ISSN | 1471-2369 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025. |
| File Version | publisher |
| PubMed ID | 40859155 |
| DOI | 10.1186/s12882-025-04405-8 |
| Web of Science KeyUT | 001559427800001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12882-025-04405-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | BEKKU, KENSUKE| YOSHINAGA, KASUMI| INOUE, SHOTA| MITSUI, YOSUKE| YAMANOI, TOMOAKI| KAWADA, TATSUSHI| TOMINAGA, YUSUKE| SADAHIRA, TAKUYA| KATAYAMA, SATOSHI| IWATA, TAKEHIRO| NISHIMURA, SHINGO| EDAMURA, KOHEI| KOBAYASHI, TOMOKO| ARAKI, MOTOO| |
| Keywords | Contrast‑enhanced CT renal cell carcinoma staging T3a downstaging |
| Published Date | 2025-08-28 |
| Publication Title | In Vivo |
| Volume | volume39 |
| Issue | issue5 |
| Publisher | International Institute of Anticancer Research |
| Start Page | 2787 |
| End Page | 2793 |
| ISSN | 0258-851X |
| NCID | AA10714348 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| PubMed ID | 40877189 |
| DOI | 10.21873/invivo.14077 |
| Web of Science KeyUT | 001578752300024 |
| Related Url | isVersionOf https://doi.org/10.21873/invivo.14077 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kawada, Tatsushi| Katayama, Satoshi| Yanagisawa, Takafumi| Mori, Keiichiro| Fukuokaya, Wataru| Komura, Kazumasa| Tsujino, Takuya| Maenosono, Ryoichi| Takahara, Kiyoshi| Nukaya, Takuhisa| Inoki, Lan| Toyoda, Shingo| Hashimoto, Takeshi| Hirasawa, Yosuke| Edamura, Kohei| Kobayashi, Tomoko| Bekku, Kensuke| Nishimura, Shingo| Iwata, Takehiro| Sadahira, Takuya| Tominaga, Yusuke| Yamanoi, Tomoaki| Yoshinaga, Kasumi| Tsuboi, Kazuma| Kobayashi, Yasuyuki| Takamoto, Atsushi| Kurose, Kyohei| Kimura, Takahiro| Azuma, Haruhito| Shiroki, Ryoichi| Fujita, Kazutoshi| Ohno, Yoshio| Araki, Motoo| |
| Keywords | Renal cell carcinoma Immune checkpoint inhibitor ICI Eosinophil Immune-related adverse event Treatment-related adverse event |
| Published Date | 2025-07-25 |
| Publication Title | Scientific Reports |
| Volume | volume15 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 27163 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025 |
| File Version | publisher |
| PubMed ID | 40715213 |
| DOI | 10.1038/s41598-025-08767-9 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-025-08767-9 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mitsui, Masao| Sekito, Takanori| Maruhashi, Mai| Maruyama, Yuki| Iwata, Takehiro| Tominaga, Yusuke| Katayama, Satoshi| Nishimura, Shingo| Bekku, Kensuke| Araki, Motoo| Hirakawa, Hidetada| Sadahira, Takuya| |
| Keywords | fimbriae urinary tract infection drug resistance virulence uropathogenic Escherichia coli |
| Published Date | 2025-05-06 |
| Publication Title | Antibiotics |
| Volume | volume14 |
| Issue | issue5 |
| Publisher | MDPI AG |
| Start Page | 468 |
| ISSN | 2079-6382 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 by the authors. |
| File Version | publisher |
| PubMed ID | 40426535 |
| DOI | 10.3390/antibiotics14050468 |
| Web of Science KeyUT | 001496482900001 |
| Related Url | isVersionOf https://doi.org/10.3390/antibiotics14050468 |
| FullText URL | fulltext.pdf suppl.docx |
|---|---|
| Author | Tsuboi, Ichiro| Matsukawa, Akihiro| Parizi, Mehdi Kardoust| Miszczyk, Marcin| Fazekas, Tamás| Schulz, Robert J| Laukhtina, Ekaterina| Kawada, Tatsushi| Katayama, Satoshi| Iwata, Takehiro| Bekku, Kensuke| Rajwa, Pawel| Wada, Koichiro| Oberneder, Katharina| Chlosta, Piotr| Karakiewicz, Pierre I.| Araki, Motoo| Shariat, Shahrokh F.| |
| Keywords | Concomitant medications Proton pump inhibitors Antibiotics steroids Opioids Histamine type-2 receptor antagonists Immune checkpoint inhibitors Urothelial carcinoma |
| Published Date | 2025-04-28 |
| Publication Title | BMC Urology |
| Volume | volume25 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 107 |
| ISSN | 1471-2490 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025. |
| File Version | publisher |
| PubMed ID | 40296069 |
| DOI | 10.1186/s12894-025-01754-2 |
| Web of Science KeyUT | 001478272600002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12894-025-01754-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mitsui, Masao| Sadahira, Takuya| Nagasaki, Naoya| Maruyama, Yuki| Sekito, Takanori| Iwata, Takehiro| Katayama, Satoshi| Bekku, Kensuke| Araki, Motoo| |
| Keywords | cefazolin postoperative infections prophylactic antibiotics prostate robotic-assisted radical prostatectomy |
| Published Date | 2024-11-18 |
| Publication Title | International Journal of Urology |
| Volume | volume32 |
| Issue | issue3 |
| Publisher | Wiley |
| Start Page | 258 |
| End Page | 263 |
| ISSN | 0919-8172 |
| NCID | AA11042471 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The Author(s). |
| File Version | publisher |
| PubMed ID | 39555690 |
| DOI | 10.1111/iju.15635 |
| Web of Science KeyUT | 001358046200001 |
| Related Url | isVersionOf https://doi.org/10.1111/iju.15635 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Bekku, Kensuke| Inoue, Shota| Yoshinaga, Kasumi| Yamanoi, Tomoaki| Mitsui, Yosuke| Kawada, Tatsushi| Tominaga, Yusuke| Sadahira, Takuya| Iwata, Takehiro| Katayama, Satoshi| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Araki, Motoo| |
| Keywords | small renal mass partial nephrectomy ablation therapy tumor location endophytic tumor |
| Published Date | 2025-06-04 |
| Publication Title | Medicine International |
| Volume | volume5 |
| Issue | issue4 |
| Publisher | Spandidos Publications |
| Start Page | 48 |
| ISSN | 2754-3242 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Bekku et al. |
| File Version | publisher |
| PubMed ID | 40529723 |
| DOI | 10.3892/mi.2025.247 |
| Related Url | isVersionOf https://doi.org/10.3892/mi.2025.247 |
| Title Alternative | The advances in robot-assisted surgery in the field of urology and future perspective |
|---|---|
| Author | Bekku, Kensuke| Nagasaki, Naoya| Okamoto, Yusuke| Shiraishi, Hiromasa| Taira, Aya| Inoue, Shota| Kawago, Yuya| Watanabe, Tomofumi| Mitsui, Masao| Horii, Satoshi| Moriwake, Takatoshi| Yoshinaga, Kasumi| Mitsui, Yosuke| Yamanoi, Tomoaki| Kawada, Tatsushi| Sadahira, Takuya| Tominaga, Yusuke| Iwata, Takehiro| Katayama, Satoshi| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Araki, Motoo| |
| Keywords | ロボット手術 ダビンチ 泌尿器科領域 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2025-04-01 |
| Volume | volume137 |
| Issue | issue1 |
| Start Page | 25 |
| End Page | 29 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.137.25 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2025 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.137.25 |
| JaLCDOI | 10.18926/AMO/68646 |
|---|---|
| FullText URL | 79_2_081.pdf |
| Author | Kawada, Tatsushi| Kobayashi, Yasuyuki| Tsugawa, Takuji| Tsuboi, Kazuma| Katayama, Satoshi| Iwata, Takehiro| Bekku, Kensuke| Kobayashi, Tomoko| Edamura, Kohei| Ebara, Shin| Araki, Motoo| |
| Abstract | We retrospectively evaluated the oncologic outcomes of paclitaxel, cisplatin, and gemcitabine (PCG) with those of gemcitabine and cisplatin (GC) as neoadjuvant chemotherapy in muscle-invasive bladder cancer (MIBC) patients. The primary outcome was efficacy: pathological complete response (pCR), ypT0N0; and pathological objective response (pOR), ypT0N0, ≤ ypT1N0, or ypT0N1. Secondary outcomes included overall survival (OS), recurrence-free survival (RFS), predictive factors for pOR, OS, and RFS, and hematologic adverse events (AEs). Among 113 patients treated (PCG, n=28; GC, n=85), similar pOR and pCR rates were achieved by the groups (pOR: PCG, 57.1% vs. GC, 49. 4%; p=0.52; pCR: PCG, 39.3% vs. GC, 29.4%; p=0.36). No significant differences were observed in OS (p=1.0) or RFS (p=0.20). Multivariate logistic regression analysis showed that hydronephrosis (odds ratio [OR] 0.32, 95%CI: 0.11-0.92) and clinical node-positive status (cN+) (OR 0.22, 95%CI: 0.050-0.99) were significantly associated with a decreased probability of pOR. On multivariate Cox regression analyses, pOR achievement was associated with improved OS (hazard ratio [HR] 0.23, 95%CI: 0.10-0.56) and RFS (HR 0.30, 95%CI: 0.13-0.67). There were no significant between-group differences in the incidence of grade ≥ 3 hematologic AEs or dose-reduction required, but the PCG group had a higher incidence of grade 4 neutropenia. |
| Keywords | urothelial carcinoma paclitaxel cisplatin gemcitabine neoadjuvant |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-04 |
| Volume | volume79 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 81 |
| End Page | 92 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40302279 |
| Web of Science KeyUT | 001485544200003 |
| Author | Oguni, Kohei| Fukushima, Shinnosuke| Hagiya, Hideharu| Kato, Atsushi| Suyama, Atsuhito| Iwata, Takehiro| Miyawaki, Yoshia| Ono, Sawako| Iio, Koji| Otsuka, Fumio| |
|---|---|
| Keywords | Cryptococcosis Fluconazole Glucocorticoids Prostatitis Tocilizumab |
| Note | © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2026.| |
| Published Date | 2025-01 |
| Publication Title | Journal of Infection and Chemotherapy |
| Volume | volume31 |
| Issue | issue1 |
| Publisher | Elsevier |
| Start Page | 102494 |
| ISSN | 1341-321X |
| NCID | AA11057978 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. |
| File Version | author |
| PubMed ID | 39152054 |
| DOI | 10.1016/j.jiac.2024.08.009 |
| Web of Science KeyUT | 001419817400001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jiac.2024.08.009 |
| JaLCDOI | 10.18926/AMO/67868 |
|---|---|
| FullText URL | 78_6_429.pdf |
| Author | Kubota, Risa| Bekku, Kensuke| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Araki, Motoo| |
| Abstract | Although partial nephrectomy (PN) is preferred over radical nephrectomy (RN) for preserving renal function in patients with cT1 renal cancer, its impact on cardiovascular events (CVe) remains controversial. This study aimed to compare PN and RN in regard to the occurrence of CVe, including cerebrovascular events and exacerbation of hypertension (HT). We retrospectively analyzed 418 consecutive patients who underwent PN or RN for cT1 renal cancer. Propensity score-matching analysis was used to adjust for imbalances between patients who underwent PN and RN, leaving 102 patients in each group. The 5-year probability of cumulative CVe incidence was 6% in the PN group and 12% in the RN group (p=0.03), with a median follow-up of 73.5 months. The statistical significance was retained after propensity score matching for patients without preoperative proteinuria (p=0.03). For all CVe including cerebrovascular events and exacerbation of HT analyzed, PN provided a lower probability of occurrence than RN in patients with small renal cancers. |
| Keywords | chronic kidney disease hypertension nephrectomy proteinuria |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-12 |
| Volume | volume78 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 429 |
| End Page | 437 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39719315 |
| Web of Science KeyUT | 001397799300001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Bekku, Kensuke| Kawada, Tatsushi| Sekito, Takanori| Yoshinaga, Kasumi| Maruyama, Yuki| Yamanoi, Tomoaki| Tominaga, Yusuke| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Araki, Motoo| Niibe, Yuzuru| |
| Keywords | renal cell carcinoma oligo-metastasis oligo-recurrence oligo-progression metastasectomy stereotactic body radiation therapy |
| Published Date | 2023-12-17 |
| Publication Title | Cancers |
| Volume | volume15 |
| Issue | issue24 |
| Publisher | MDPI |
| Start Page | 5873 |
| ISSN | 2072-6694 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 38136417 |
| DOI | 10.3390/cancers15245873 |
| Web of Science KeyUT | 001131355800001 |
| Related Url | isVersionOf https://doi.org/10.3390/cancers15245873 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakaeda, Kazuma| Sadahira, Takuya| Maruyama, Yuki| Iwata, Takehiro| Watanabe, Masami| Wada, Koichiro| Araki, Motoo| |
| Keywords | antimicrobial resistance Escherichia coli urinary tract infections flomoxef ST131 |
| Published Date | 2023-03-06 |
| Publication Title | Antibiotics |
| Volume | volume12 |
| Issue | issue3 |
| Publisher | MDPI |
| Start Page | 522 |
| ISSN | 2079-6382 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36978389 |
| DOI | 10.3390/antibiotics12030522 |
| Web of Science KeyUT | 000952995400001 |
| Related Url | isVersionOf https://doi.org/10.3390/antibiotics12030522 |
| FullText URL | fulltext20230317-1.pdf |
|---|---|
| Author | Tominaga, Yusuke| Fujii, Masanori| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Bekku, Kensuke| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Kiura, Katsuyuki| Maeda, Yoshinobu| Wada, Koichiro| Araki, Motoo| |
| Keywords | bladder tuberculosis bacillus Calmette-Guerin bladder cancer ureteral stricture voiding dysfunction |
| Published Date | 2022-12-20 |
| Publication Title | Molecular and Clinical Oncology |
| Volume | volume18 |
| Issue | issue2 |
| Publisher | Spandidos Publications |
| Start Page | 7 |
| ISSN | 2049-9450 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Tominaga et al. |
| File Version | publisher |
| PubMed ID | 36761388 |
| DOI | 10.3892/mco.2022.2603 |
| Web of Science KeyUT | 000928771000001 |
| Related Url | isVersionOf https://doi.org/10.3892/mco.2022.2603 |
| JaLCDOI | 10.18926/AMO/62820 |
|---|---|
| FullText URL | 75_6_763.pdf |
| Author | Iwata, Takehiro| Sadahira, Takuya| Maruyama, Yuki| Sekito, Takanori| Yoshinaga, Kasumi| Watari, Shogo| Nagao, Kentaro| Kawada, Tatsushi| Tominaga, Yusuke| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Ishii, Ayano| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| Wada, Koichiro| |
| Abstract | The aim of this ongoing trial is to evaluate the clinical efficacy and safety of sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, complicated pyelonephritis, bacterial prostatitis, and epididymitis. The primary endpoint is the microbiological efficacy at 5-9 days after the last administration of STFX. Recruitment began in February 2021, and the target total sample size is 92 participants. |
| Keywords | genitourinary tract infections fluoroquinolone resistance extended-spectrum beta-lactamase |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 763 |
| End Page | 766 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955548 |
| Web of Science KeyUT | 000735319800006 |
| NAID | 120007180272 |
| JaLCDOI | 10.18926/AMO/62810 |
|---|---|
| FullText URL | 75_6_705.pdf |
| Author | Iwata, Takehiro| Maruyama, Yuki| Kawada, Tatsushi| Sadahira, Takuya| Katayama, Satoshi| Takamoto, Atsushi| Sako, Tomoko| Wada, Koichiro| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| Abstract | Optimal neoadjuvant hormone therapy (NHT) for reducing prostate cancer (PC) patients’ prostate volume pre-brachytherapy is controversial. We evaluated the differential impact of neoadjuvant gonadotropin-releasing hormone (GnRH) antagonist versus agonist on post-brachytherapy testosterone recovery in 112 patients treated pre-brachytherapy with NHT (GnRH antagonist, n=32; GnRH agonists, n=80) (Jan. 2007-June 2019). We assessed the effects of patient characteristics and a GnRH analogue on testosterone recovery with logistic regression and a propensity score analysis (PSA). There was no significant difference in the rate of testosterone recovery to normal levels (> 300 ng/dL) between the GnRH antagonist and agonists (p=0.07). The GnRH agonists induced a significantly more rapid testosterone recovery rate at 3 months post-brachytherapy versus the GnRH antagonist (p<0.0001); there was no difference in testosterone recovery at 12 months between the GnRH antagonist/agonists (p=0.8). In the multivariate analysis, no actor was associated with testosterone recovery. In the PSA, older age and higher body mass index (BMI) were significantly associated with longer testosterone recovery. Post-brachytherapy testosterone recovery was quicker with the neoadjuvant GnRH agonists than the antagonist, and the testosterone recovery rate was significantly associated with older age and higher BMI. Long-term follow-ups are needed to determine any differential effects of GnRH analogues on the quality of life of brachytherapy-treated PC patients. |
| Keywords | testosterone recovery GnRH antagonist GnRH agonist brachytherapy prostate cancer |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 705 |
| End Page | 711 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955538 |
| Web of Science KeyUT | 000735297900006 |
| NAID | 120007180282 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Wada, Koichiro| Araki, Motoo| Tanimoto, Ryuta| Sadahira, Takuya| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Nakajima, Hirochika| Acosta, Herik| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| Keywords | Photodynamic diagnosis 5-Aminolevulinic acid ALA-PDD Upper urinary tract urothelial carcinoma VISERA ELITE video system |
| Published Date | 2021-03-25 |
| Publication Title | BMC urology |
| Volume | volume21 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 45 |
| ISSN | 1471-2490 |
| NCID | AA12035460 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021. |
| File Version | publisher |
| PubMed ID | 33765999 |
| DOI | 10.1186/s12894-021-00819-2 |
| NAID | 120007008530 |
| Web of Science KeyUT | 000632906900001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12894-021-00819-2 |
