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ID 48963
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66_5_387.pdf 3.02 MB
Author
Chikasue, Kumiko
Ikeda, Kazuyuki
Ohnishi, Takuma
Kawanishi, Satoshi
Kataoka, Mikio Kaken ID researchmap
Abstract
To determine whether exhaled breath contains Torque teno virus (TTV) or not, we tested exhaled breath condensate (EBC) samples by semi-nested PCR assay. We detected TTV DNA in 35% (7/20) of EBC samples collected from the mouth of one of the authors, demonstrating that TTV DNA is excreted in exhaled breath with moderate frequency. TTV DNA was detected also in oral EBC samples from 4 of 6 other authors, indicating that TTV DNA excretion in exhaled breath is not an exception but rather a common phenomenon. Furthermore, the same assay could amplify TTV DNA from room air condensate (RAC) samples collected at distances of 20 and 40cm from a human face with 40 (8/20) and 35% (7/20) positive rates, respectively. TTV transmission has been reported to occur during infancy. These distances seem equivalent to that between an infant and its household members while caring for the infant. Taken together, it seems that exhaled breath is one of the possible transmission routes of TTV. We also detected TTV DNA in 25% (10/40) of RAC samples collected at a distance of more than 180cm from any human face, suggesting the risk of airborne infection with TTV in a room.
Keywords
Torque teno virus
exhaled breath
airborne infection
polymerase chain reaction
Amo Type
Original Article
Publication Title
Acta Medica Okayama
Published Date
2012-10
Volume
volume66
Issue
issue5
Publisher
Okayama University Medical School
Start Page
387
End Page
397
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
Copyright Holders
CopyrightⒸ 2012 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT
Related Url
http://ousar.lib.okayama-u.ac.jp/metadata/49508