JaLCDOI | 10.18926/AMO/66674 |
---|---|
FullText URL | 78_1_079.pdf |
Author | Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Aoyama, Yuki| Yasutomi, Eriko| Igawa, Shoko| Inokuchi, Toshihiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Harada, Keita| Onishi, Hideki| Okada, Hiroyuki| |
Abstract | This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies. |
Keywords | transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore |
Amo Type | Short Communication |
Publication Title | Acta Medica Okayama |
Published Date | 2024-02 |
Volume | volume78 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 79 |
End Page | 83 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
FullText URL | fulltext.pdf |
---|---|
Author | Yamamoto, Shumpei| Kinugasa, Hideaki| Yamasaki, Yasushi| Hirai, Mami| Ako, Soichiro| Takei, Kensuke| Igawa, Shoko| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Inokuchi, Toshihiro| Harada, Keita| Hiraoka, Sakiko| Nouso, Kazuhiro| Tanaka, Takehiro| Okada, Hiroyuki| |
Keywords | colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever |
Published Date | 2021-12-09 |
Publication Title | DEN Open |
Volume | volume2 |
Issue | issue1 |
Publisher | Wiley |
Start Page | e83 |
ISSN | 2692-4609 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Authors. |
File Version | publisher |
PubMed ID | 35310725 |
DOI | 10.1002/deo2.83 |
Web of Science KeyUT | 001047024900091 |
Related Url | isVersionOf https://doi.org/10.1002/deo2.83 |
FullText URL | fulltext.pdf |
---|---|
Author | Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Yasutomi, Eriko| Igawa, Shoko| Yamamoto, Shumpei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Harada, Keita| Ohnishi, Hideki| Okada, Hiroyuki| |
Keywords | bowel wall thickness Mayo endoscopic subscore classification transabdominal ultrasonography ulcerative colitis |
Published Date | 2022-09-15 |
Publication Title | Internal Medicine |
Volume | volume61 |
Issue | issue18 |
Publisher | The Japanese Society of Internal Medicine |
Start Page | 2703 |
End Page | 2709 |
ISSN | 0918-2918 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 35185047 |
DOI | 10.2169/internalmedicine.8827-21 |
Web of Science KeyUT | 000857218300001 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.8827-21 |
FullText URL | fulltext.pdf |
---|---|
Author | Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Fumio| Okada, Hiroyuki| |
Keywords | central memory T cell flow cytometry natural killer T cells peripheral blood mononuclear cell ulcerative colitis |
Published Date | 2022-01-12 |
Publication Title | International Journal of Immunopathology and Pharmacology |
Volume | volume36 |
Publisher | Sage Publications Inc. |
Start Page | 1 |
End Page | 12 |
ISSN | 0394-6320 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022 |
File Version | publisher |
PubMed ID | 35021918 |
DOI | 10.1177/20587384211051982 |
Web of Science KeyUT | 000747491200001 |
Related Url | isVersionOf https://doi.org/10.1177/20587384211051982 |
FullText URL | fulltext.pdf |
---|---|
Author | Yasutomi, Eriko| Inokuchi, Toshihiro| Hiraoka, Sakiko| Takei, Kensuke| Igawa, Shoko| Yamamoto, Shumpei| Ohmori, Masayasu| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Furukawa, Masaki| Itoshima, Kouichi| Okada, Ken| Otsuka, Fumio| Tanaka, Takehiro| Mitsuhashi, Toshiharu| Kato, Jun| Okada, Hiroyuki| |
Published Date | 2021-05-27 |
Publication Title | Scientific Reports |
Volume | volume11 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 11086 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2021 |
File Version | publisher |
PubMed ID | 34045529 |
NAID | 120007089817 |
DOI | 10.1038/s41598-021-90441-x |
Web of Science KeyUT | 000658389400001 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-021-90441-x |
FullText URL | fulltext.pdf |
---|---|
Author | Iwamuro, Masaya| Tanaka, Takehiro| Sugihara, Yuusaku| Harada, Keita| Hiraoka, Sakiko| Kondo, Yoshitaka| Okada, Hiroyuki| |
Keywords | endometriosis subepithelial lesion submucosal tumor cecum colonoscopy |
Published Date | 2021 |
Publication Title | Internal Medicine |
Volume | volume60 |
Issue | issue11 |
Publisher | Japanese Society of Internal Medicine |
Start Page | 1697 |
End Page | 1701 |
ISSN | 0918-2918 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 33390498 |
DOI | 10.2169/internalmedicine.6418-20 |
Web of Science KeyUT | 000659353300007 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.6418-20 |
FullText URL | fulltext.pdf |
---|---|
Author | Hiraoka, Sakiko| Takashima, Shiho| Inokuchi, Toshihiro| Nakarai, Asuka| Takahara, Masahiro| Harada, Keita| Seki, Yasuhiro| Watanabe, Katsunori| Kato, Jun| Okada, Hiroyuki| |
Keywords | Colitis ulcerative Fecal calprotectin Quantitative fecal immunochemical test Latex agglutination turbidimetric immunoassay Mucosal healing |
Published Date | 2018-12-14 |
Publication Title | Intestinal Research |
Volume | volume17 |
Issue | issue2 |
Publisher | Korean Association for the Study of Intestinal Diseases |
Start Page | 202 |
End Page | 209 |
ISSN | 1598-9100 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Copyright 2019. Korean Association for the Study of Intestinal Diseases |
File Version | publisher |
PubMed ID | 30541228 |
DOI | 10.5217/ir.2018.00086 |
Web of Science KeyUT | 000466136800006 |
Related Url | isVersionOf https://doi.org/10.5217/ir.2018.00086 |
FullText URL | fulltext.pdf |
---|---|
Author | Sugihara, Yuusaku| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Morito, Yuki| Takahashi, Sakuma| Harada, Keita| Tanaka, Takehiro| Otsuka, Fumio| Okada, Hiroyuki| |
Keywords | graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy |
Published Date | 2020-02-21 |
Publication Title | Experimental and Therapeutic Medicine |
Volume | volume19 |
Issue | issue4 |
Publisher | Spandidos Publications |
Start Page | 3076 |
End Page | 3080 |
ISSN | 1792-0981 |
NCID | AA12610820 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Sugiharaet al. |
File Version | publisher |
PubMed ID | 32256795 |
DOI | 10.3892/etm.2020.8538 |
Web of Science KeyUT | 000523637100082 |
Related Url | isVersionOf https://doi.org/10.3892/etm.2020.8538 |
FullText URL | fulltext.pdf |
---|---|
Author | Iwamuro, Masaya| Tanaka, Takehiro| Yamauchi, Nao| Nakashima, Yuri| Wada, Takahira| Hiraoka, Sakiko| Kawahara, Yoshiro| Okada, Hiroyuki| |
Keywords | cytomegalovirus colitis pseudolipomatosis gastric emphysema post-resuscitation diabetes mellitus |
Published Date | 2020-02-15 |
Publication Title | Internal Medicine |
Volume | volume59 |
Issue | issue4 |
Publisher | The Japanese Society of Internal Medicine |
Start Page | 519 |
End Page | 525 |
ISSN | 0918-2918 |
NCID | AA10827774 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 31645533 |
NAID | 130007798412 |
DOI | 10.2169/internalmedicine.3633-19 |
Web of Science KeyUT | 000516549400009 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.3633-19 |
FullText URL | fulltext.pdf |
---|---|
Author | Kinugasa, Hideaki| Hiraoka, Sakiko| Nouso, Kazuhiro| Yamamoto, Shumpei| Hirai, Mami| Terasawa, Hiroyuki| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Harada, Keita| Tanaka, Takehiro| Okada, Hiroyuki| |
Keywords | IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA |
Published Date | 2020-12-03 |
Publication Title | BMC Cancer |
Volume | volume20 |
Issue | issue1 |
Publisher | BMC |
Start Page | 1188 |
ISSN | 1471-2407 |
NCID | AA12034763 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2020 |
File Version | publisher |
PubMed ID | 33272240 |
DOI | 10.1186/s12885-020-07699-z |
Web of Science KeyUT | 000597268700004 |
Related Url | isVersionOf https://doi.org/10.1186/s12885-020-07699-z |
FullText URL | fulltext.pdf |
---|---|
Author | Iwamuro, Masaya| Takahashi, Takahide| Tanaka, Takehiro| Toji, Tomohiro| Hiraoka, Sakiko| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
Published Date | 2020-10-07 |
Publication Title | Case Reports in Gastrointestinal Medicine |
Volume | volume2020 |
Publisher | Hindawi |
Start Page | 8893604 |
ISSN | 2090-6528 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Masaya Iwamuro et al. |
File Version | publisher |
PubMed ID | 33083067 |
DOI | 10.1155/2020/8893604 |
Web of Science KeyUT | 000583201400001 |
Related Url | isVersionOf https://doi.org/10.1155/2020/8893604 |
JaLCDOI | 10.18926/AMO/60363 |
---|---|
FullText URL | 74_4_265.pdf |
Author | Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun| |
Abstract | Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy. |
Keywords | Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 265 |
End Page | 274 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843757 |
Web of Science KeyUT | 000562508700001 |
NAID | 120006880202 |
FullText URL | fulltext.pdf |
---|---|
Author | Yasutomi, Eriko| Hiraoka, Sakiko| Yamamoto, Shumpei| Oka, Shohei| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Kato, Jun| Okada, Hiroyuki| |
Keywords | ulcerative colitis salicylates mesalazine sulfasalazine |
Published Date | 2019-12-02 |
Publication Title | Journal of Clinical Medicine |
Volume | volume8 |
Issue | issue12 |
Publisher | MDPI |
ISSN | 2077-0383 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2019 by the authors. |
File Version | publisher |
PubMed ID | 31810227 |
DOI | 10.3390/jcm8122109 |
Web of Science KeyUT | 000506640400082 |
Related Url | isVersionOf https://doi.org/10.3390/jcm8122109 |
FullText URL | SR9_1_11934.pdf |
---|---|
Author | Takahara, Masahiro| Takaki, Akinobu| Hiraoka, Sakiko| Adach, Takuya| Shimomura, Yasuyuki| Matsushita, Hiroshi| Nguyen Tien Thi Thuy| Koike, Kazuko| Ikeda, Airi| Takashima, Shiho| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Sugihara, Yusaku| Harada, Keita| Eikawa, Shingo| Morita, Hidetoshi| Udono, Heiichiro| Okada, Hiroyuki| |
Published Date | 2019-8-15 |
Publication Title | Scientific Reports |
Volume | volume9 |
Publisher | Nature Publishing Group |
Start Page | 11934 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2019 |
File Version | publisher |
PubMed ID | 31417110 |
DOI | 10.1038/s41598-019-48331-w |
Web of Science KeyUT | 000480680800048 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-019-48331-w |
JaLCDOI | 10.18926/AMO/57377 |
---|---|
FullText URL | 73_5_457.pdf |
Author | Iwamuro, Masaya| Takahara, Masahiro| Yamazaki, Tatsuhiro| Tanaka, Takehiro| Kondo, Yoshitaka| Hiraoka, Sakiko| Okada, Hiroyuki| |
Abstract | A 60-year-old Caucasian male was diagnosed with lung adenocarcinoma and multiple metastases to the bone, spleen, and brain. He underwent radiotherapy for the brain and lumbar spine metastases, plus chemotherapy (cisplatin and pemetrexed). The chemotherapy was discontinued due to vomiting and hyponatremia, and nivolumab was then administered. Eight months later, 18F-fluorodeoxyglucose positron emission tomography showed tracer uptake in the colon. Colonoscopy revealed a reddish multinodular polyp in the sigmoid colon. The polyp showed irregular microvessels. No colonic mucosal surface structures were observed. Colonic metastasis of the lung carcinoma was highly suspected; the polyp was therefore surgically removed. The histological analysis revealed granulation tissue and suppurative inflammation without neoplastic changes. We diagnosed the lesion as a granulation polyp. Despite the difficulty in diagnosing these lesions due to their rarity and similarity to metastatic colon tumors, we suggest that recognizing the endoscopic features of the polyp surface may allow a preoperative diagnosis. |
Keywords | colonoscopy colonic neoplasms granulation polyp |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2019-10 |
Volume | volume73 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 457 |
End Page | 461 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 31649373 |
Web of Science KeyUT | 000491886600012 |
JaLCDOI | 10.18926/AMO/55436 |
---|---|
FullText URL | 71_5_391.pdf |
Author | Iwamuro, Masaya| Takata, Katsuyoshi| Hayashi, Eiko| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Yoshino, Tadashi| Okada, Hiroyuki| |
Abstract | To evaluate the usefulness of colonoscopy for the detection of ileal involvement in patients with intestinal follicular lymphoma, seventeen patients with intestinal follicular lymphoma who underwent colonoscopy and biopsy sampling from the terminal ileum were enrolled. The patients were divided into 2 groups: cases with ileal involvement (n=6) and cases without ileal involvement (n=11). Patients’ clinical backgrounds were compared between the two groups. Subsequently, 10 board-certified endoscopists independently evaluated the endoscopic pictures and determined whether the ileum was involved with follicular lymphoma. Infiltration of follicular lymphoma cells were identified in 6 patients (35.3%). Cases with positive ileal involvement were diagnosed with follicular lymphoma at a younger age than were cases without ileal involvement (55.4±7.4 vs. 68.1±10.3 years, p=0.011). Macroscopically, in patients with ileal involvement, there were multiple polypoid elevations smaller than 5 mm in 4 cases, single polypoid elevation smaller than 5 mm in 1 case, and single polypoid elevation larger than 5 mm in 1 case. In patients without ileal involvement, there were no lesions in the terminal ileum in 7 cases, and multiple polypoid elevations smaller than 5 mm were seen in 4 cases. The accuracy of the macroscopic evaluation by 10 board-certified endoscopists was 68.8%. Colonoscopy is particularly recommended during the initial workup of patients with follicular lymphoma diagnosed at age ≤ 60 years. The diagnosis of ileal involvement based on morphology alone is difficult; thus, biopsy and pathologic diagnosis are required for accurate diagnosis. |
Keywords | follicular lymphoma colonoscopy ileal neoplasms terminal ileum small intestine |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2017-10 |
Volume | volume71 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 391 |
End Page | 398 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 29042696 |
JaLCDOI | 10.18926/AMO/53912 |
---|---|
FullText URL | 69_6_365.pdf |
Author | Kawano, Seiji| Hiraoka, Sakiko| Okada, Hiroyuki| Akita, Mitsuhiro| Iwamuro, Masaya| Yamamoto, Kazuhide| |
Abstract | Several studies have identified a relationship between myelodysplastic syndrome and Behçetʼs disease (BD), especially intestinal BD, and trisomy 8 appears to play an important role in these disorders. Despite this, only few case reports or series have been reported in gastroenterology, meaning that endoscopic findings and characteristics of intestinal BD have not been clarified yet. In this report, we describe three cases of intestinal BD associated with myelodysplastic syndrome and trisomy 8, and discuss the clinical features and problems of these disorders from a gastroenterology perspective. |
Keywords | Behçetʼs disease trisomy 8 myelodysplastic syndrome |
Amo Type | Case Reports |
Publication Title | Acta Medica Okayama |
Published Date | 2015-12 |
Volume | volume69 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 365 |
End Page | 369 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 26690248 |
Web of Science KeyUT | 000368434500007 |
Author | Saito, Shunsuke| Kato, Jun| Hiraoka, Sakiko| Horii, Joichiro| Suzuki, Hideyuki| Higashi, Reiji| Kaji, Eisuke| Kondo, Yoshitaka| Yamamoto, Kazuhide| |
---|---|
Published Date | 2011-09 |
Publication Title | Inflammatory Bowel Diseases |
Volume | volume17 |
Issue | issue9 |
Content Type | Journal Article |
Author | Nakarai, Asuka| Kato, Jun| Hiraoka, Sakiko| Kuriyama, Motoaki| Inokuchi, Toshihiro| Takei, Daisuke| Moritou, Yuki| Akita, Mitsuhiro| Takahashi, Sakuma| Harada, Keita| Okada, Hiroyuki| Yamamoto, Kazuhide| |
---|---|
Published Date | 2013-12-02 |
Publication Title | 岡山医学会雑誌 |
Volume | volume125 |
Issue | issue3 |
Content Type | Journal Article |
JaLCDOI | 10.18926/AMO/51864 |
---|---|
FullText URL | 67_5_285.pdf |
Author | Akita, Mitsuhiro| Hiraoka, Sakiko| Kaji, Eisuke| Takemoto, Koji| Nagahara, Yasuhiro| Yamamoto, Hiroshi| Yamamoto, Kazuhide| Kato, Jun| |
Abstract | Whether presence or history of extracolonic primary malignancy is a risk for colorectal neoplasia is not fully known. In this study, 26,452 first-time colonoscopy cases were examined using a colonoscopy database. Among the analyzed subjects, 3,026 (11%) subjects had history or concomitance of extracolonic primary malignancy, while the remaining 23,426 subjects did not. Colorectal neoplasia was observed in 39% of all the subjects. A crude comparison showed that the prevalence of any type of colorectal neoplasia was higher in subjects with extracolonic malignancy than in those without (42% vs. 39%, p=0.0012). However, after adjusting for confounding factors, the odds ratios (ORs) of subjects with extracolonic malignancy for having colorectal neoplasia, advanced neoplasia, and cancer were all less than 1.0, and all significantly different from those of subjects without extracolonic malignancy. Analysis according to the type of extracolonic malignancy revealed that gastric cancer cases had a significantly lower risk for colorectal advanced neoplasia (OR:0.81;95% CI:0.67-0.99). Among major malignancies, only esophageal squamous cell cancer cases had increased risk for colorectal neoplasia (OR:1.66;95% CI:1.20-2.29). Patients with presence or history of extracolonic malignancy did not carry a higher risk of occurrence of colorectal neoplasia. |
Keywords | colorectal cancer colonoscopy risk factor database |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2013-10 |
Volume | volume67 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 285 |
End Page | 292 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 24145728 |
Web of Science KeyUT | 000325836100002 |