FullText URL fulltext.pdf
Author Honda, Manami| Iwamuro, Masaya| Tanaka, Takehiro| Yamasaki, Yasushi| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Otsuka, Motoyuki|
Keywords colonoscopy esophagogastroduodenoscopy gastrointestinal neoplasms gastrointestinal stromal tumor neurofibromatosis
Published Date 2025-04-16
Publication Title JGH Open
Volume volume9
Issue issue4
Publisher Wiley
Start Page e70151
ISSN 2397-9070
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40247846
DOI 10.1002/jgh3.70151
Web of Science KeyUT 001468535400001
Related Url isVersionOf https://doi.org/10.1002/jgh3.70151
FullText URL fulltext.pdf
Author Igawa, Shoko| Inokuchi, Toshihiro| Hiraoka, Sakiko| Toyosawa, Junki| Aoyama, Yuki| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahara, Masahiro| Okada, Hiroyuki| Otsuka, Motoyuki|
Keywords biologics therapy tacrolimus thiopurine ulcerative colitis
Published Date 2025-04-02
Publication Title JGH Open
Volume volume9
Issue issue4
Publisher Wiley
Start Page e70139
ISSN 2397-9070
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40177188
DOI 10.1002/jgh3.70139
Web of Science KeyUT 001457389100001
Related Url isVersionOf https://doi.org/10.1002/jgh3.70139
FullText URL fulltext.pdf
Author Aoyama, Yuki| Hiraoka, Sakiko| Yasutomi, Eriko| Inokuchi, Toshihiro| Tanaka, Takehiro| Takei, Kensuke| Igawa, Shoko| Takeuchi, Keiko| Takahara, Masahiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Kato, Jun| Okada, Hiroyuki| Otsuka, Motoyuki|
Keywords Ulcerative colitis Leucine-rich alpha 2 glycoprotein Biomarker
Published Date 2025-02-12
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 5248
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 39939376
DOI 10.1038/s41598-025-89615-8
Web of Science KeyUT 001421220800034
Related Url isVersionOf https://doi.org/10.1038/s41598-025-89615-8
FullText URL fulltext20250108-02.pdf fig20250108-02.pdf table20250108-02.pdf
Author Toyosawa, Junki| Yamasaki, Yasushi| Aoyama, Yuki| Takei, Kensuke| Igawa, Shoko| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Hiraoka, Sakiko| Okada, Hiroyuki| Otsuka, Motoyuki|
Keywords Underwater endoscopic mucosal resection Endoscopic mucosal resection Cold snare polypectomy
Note This is the accepted manuscript version of an article published by Karger Publishers in [Junki Toyosawa, Yasushi Yamasaki, Yuki Aoyama, Kensuke Takei, Shoko Igawa, Toshihiro Inokuchi, Hideaki Kinugasa, Masahiro Takahara, Sakiko Hiraoka, Hiroyuki Okada, Motoyuki Otsuka; Adverse Events after Different Endoscopic Resection Procedures for Small and Intermediate-Sized Colorectal Polyps. Dig Dis 2 December 2024; 42 (6): 529–537. https://doi.org/10.1159/000540365] and available on karger.com/Article/FullText/doi.|
Published Date 2024-08-09
Publication Title Digestive Diseases
Volume volume42
Issue issue6
Publisher S. Karger AG
Start Page 529
End Page 537
ISSN 0257-2753
NCID AA10725752
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 S. Karger AG, Basel
File Version author
PubMed ID 39128468
DOI 10.1159/000540365
Web of Science KeyUT 001374461700001
Related Url isVersionOf https://doi.org/10.1159/000540365
Title Alternative Ulcerative colitis
Author Hiraoka, Sakiko|
Keywords 潰瘍性大腸炎 炎症性腸疾患 診断 治療
Publication Title Journal of Okayama Medical Association
Published Date 2024-12-02
Volume volume136
Issue issue3
Start Page 132
End Page 134
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.132
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.132
Title Alternative A case of immune checkpoint inhibitor-associated colitis treated with infliximab
Author Iwamuro, Masaya| Hiraoka, Sakiko| Otsuka, Motoyuki|
Abstract  A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary.
Keywords インフリキシマブ(infliximab) 免疫関連有害事象(immune-related adverse events) 大腸炎(colitis)
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 69
End Page 73
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.69
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.69
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-Ichi| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Motoyuki|
Keywords Colonoscopy Esophagogastroduodenoscopy Graft-versus-host disease Hematopoietic stem cell transplantation Intestinal transplant-associated microangiopathy iTAM
Note The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-024-03221-y|
Published Date 2024-04-22
Publication Title BMC Gastroenterology
Volume volume24
Issue issue1
Publisher BMC
Start Page 140
ISSN 1471-230X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38649868
DOI 10.1186/s12876-024-03221-y
Web of Science KeyUT 001206319800003
Related Url isVersionOf https://doi.org/10.1186/s12876-024-03221-y
JaLCDOI 10.18926/AMO/66674
FullText URL 78_1_079.pdf
Author Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Aoyama, Yuki| Yasutomi, Eriko| Igawa, Shoko| Inokuchi, Toshihiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Harada, Keita| Onishi, Hideki| Okada, Hiroyuki|
Abstract This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies.
Keywords transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore
Amo Type Short Communication
Publication Title Acta Medica Okayama
Published Date 2024-02
Volume volume78
Issue issue1
Publisher Okayama University Medical School
Start Page 79
End Page 83
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38419318
Web of Science KeyUT 001203658200004
FullText URL fulltext.pdf
Author Yamamoto, Shumpei| Kinugasa, Hideaki| Yamasaki, Yasushi| Hirai, Mami| Ako, Soichiro| Takei, Kensuke| Igawa, Shoko| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Inokuchi, Toshihiro| Harada, Keita| Hiraoka, Sakiko| Nouso, Kazuhiro| Tanaka, Takehiro| Okada, Hiroyuki|
Keywords colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever
Published Date 2021-12-09
Publication Title DEN Open
Volume volume2
Issue issue1
Publisher Wiley
Start Page e83
ISSN 2692-4609
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Authors.
File Version publisher
PubMed ID 35310725
DOI 10.1002/deo2.83
Web of Science KeyUT 001047024900091
Related Url isVersionOf https://doi.org/10.1002/deo2.83
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Author Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Yasutomi, Eriko| Igawa, Shoko| Yamamoto, Shumpei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Harada, Keita| Ohnishi, Hideki| Okada, Hiroyuki|
Keywords bowel wall thickness Mayo endoscopic subscore classification transabdominal ultrasonography ulcerative colitis
Published Date 2022-09-15
Publication Title Internal Medicine
Volume volume61
Issue issue18
Publisher The Japanese Society of Internal Medicine
Start Page 2703
End Page 2709
ISSN 0918-2918
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 35185047
DOI 10.2169/internalmedicine.8827-21
Web of Science KeyUT 000857218300001
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.8827-21
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Fumio| Okada, Hiroyuki|
Keywords central memory T cell flow cytometry natural killer T cells peripheral blood mononuclear cell ulcerative colitis
Published Date 2022-01-12
Publication Title International Journal of Immunopathology and Pharmacology
Volume volume36
Publisher Sage Publications Inc.
Start Page 1
End Page 12
ISSN 0394-6320
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 35021918
DOI 10.1177/20587384211051982
Web of Science KeyUT 000747491200001
Related Url isVersionOf https://doi.org/10.1177/20587384211051982
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Author Yasutomi, Eriko| Inokuchi, Toshihiro| Hiraoka, Sakiko| Takei, Kensuke| Igawa, Shoko| Yamamoto, Shumpei| Ohmori, Masayasu| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Furukawa, Masaki| Itoshima, Kouichi| Okada, Ken| Otsuka, Fumio| Tanaka, Takehiro| Mitsuhashi, Toshiharu| Kato, Jun| Okada, Hiroyuki|
Published Date 2021-05-27
Publication Title Scientific Reports
Volume volume11
Issue issue1
Publisher Nature Research
Start Page 11086
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 34045529
NAID 120007089817
DOI 10.1038/s41598-021-90441-x
Web of Science KeyUT 000658389400001
Related Url isVersionOf https://doi.org/10.1038/s41598-021-90441-x
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Sugihara, Yuusaku| Harada, Keita| Hiraoka, Sakiko| Kondo, Yoshitaka| Okada, Hiroyuki|
Keywords endometriosis subepithelial lesion submucosal tumor cecum colonoscopy
Published Date 2021
Publication Title Internal Medicine
Volume volume60
Issue issue11
Publisher Japanese Society of Internal Medicine
Start Page 1697
End Page 1701
ISSN 0918-2918
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 33390498
DOI 10.2169/internalmedicine.6418-20
Web of Science KeyUT 000659353300007
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.6418-20
FullText URL fulltext.pdf
Author Hiraoka, Sakiko| Takashima, Shiho| Inokuchi, Toshihiro| Nakarai, Asuka| Takahara, Masahiro| Harada, Keita| Seki, Yasuhiro| Watanabe, Katsunori| Kato, Jun| Okada, Hiroyuki|
Keywords Colitis ulcerative Fecal calprotectin Quantitative fecal immunochemical test Latex agglutination turbidimetric immunoassay Mucosal healing
Published Date 2018-12-14
Publication Title Intestinal Research
Volume volume17
Issue issue2
Publisher Korean Association for the Study of Intestinal Diseases
Start Page 202
End Page 209
ISSN 1598-9100
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2019. Korean Association for the Study of Intestinal Diseases
File Version publisher
PubMed ID 30541228
DOI 10.5217/ir.2018.00086
Web of Science KeyUT 000466136800006
Related Url isVersionOf https://doi.org/10.5217/ir.2018.00086
FullText URL fulltext.pdf
Author Sugihara, Yuusaku| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Morito, Yuki| Takahashi, Sakuma| Harada, Keita| Tanaka, Takehiro| Otsuka, Fumio| Okada, Hiroyuki|
Keywords graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy
Published Date 2020-02-21
Publication Title Experimental and Therapeutic Medicine
Volume volume19
Issue issue4
Publisher Spandidos Publications
Start Page 3076
End Page 3080
ISSN 1792-0981
NCID AA12610820
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Sugiharaet al.
File Version publisher
PubMed ID 32256795
DOI 10.3892/etm.2020.8538
Web of Science KeyUT 000523637100082
Related Url isVersionOf https://doi.org/10.3892/etm.2020.8538
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Yamauchi, Nao| Nakashima, Yuri| Wada, Takahira| Hiraoka, Sakiko| Kawahara, Yoshiro| Okada, Hiroyuki|
Keywords cytomegalovirus colitis pseudolipomatosis gastric emphysema post-resuscitation diabetes mellitus
Published Date 2020-02-15
Publication Title Internal Medicine
Volume volume59
Issue issue4
Publisher The Japanese Society of Internal Medicine
Start Page 519
End Page 525
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 by The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 31645533
NAID 130007798412
DOI 10.2169/internalmedicine.3633-19
Web of Science KeyUT 000516549400009
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.3633-19
FullText URL fulltext.pdf
Author Kinugasa, Hideaki| Hiraoka, Sakiko| Nouso, Kazuhiro| Yamamoto, Shumpei| Hirai, Mami| Terasawa, Hiroyuki| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Harada, Keita| Tanaka, Takehiro| Okada, Hiroyuki|
Keywords IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA
Published Date 2020-12-03
Publication Title BMC Cancer
Volume volume20
Issue issue1
Publisher BMC
Start Page 1188
ISSN 1471-2407
NCID AA12034763
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2020
File Version publisher
PubMed ID 33272240
DOI 10.1186/s12885-020-07699-z
Web of Science KeyUT 000597268700004
Related Url isVersionOf https://doi.org/10.1186/s12885-020-07699-z
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takahashi, Takahide| Tanaka, Takehiro| Toji, Tomohiro| Hiraoka, Sakiko| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Published Date 2020-10-07
Publication Title Case Reports in Gastrointestinal Medicine
Volume volume2020
Publisher Hindawi
Start Page 8893604
ISSN 2090-6528
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Masaya Iwamuro et al.
File Version publisher
PubMed ID 33083067
DOI 10.1155/2020/8893604
Web of Science KeyUT 000583201400001
Related Url isVersionOf https://doi.org/10.1155/2020/8893604
JaLCDOI 10.18926/AMO/60363
FullText URL 74_4_265.pdf
Author Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun|
Abstract Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy.
Keywords Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-08
Volume volume74
Issue issue4
Publisher Okayama University Medical School
Start Page 265
End Page 274
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32843757
Web of Science KeyUT 000562508700001
NAID 120006880202
FullText URL fulltext.pdf
Author Yasutomi, Eriko| Hiraoka, Sakiko| Yamamoto, Shumpei| Oka, Shohei| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Kato, Jun| Okada, Hiroyuki|
Keywords ulcerative colitis salicylates mesalazine sulfasalazine
Published Date 2019-12-02
Publication Title Journal of Clinical Medicine
Volume volume8
Issue issue12
Publisher MDPI
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 by the authors.
File Version publisher
PubMed ID 31810227
DOI 10.3390/jcm8122109
Web of Science KeyUT 000506640400082
Related Url isVersionOf https://doi.org/10.3390/jcm8122109