FullText URL | fulltext.pdf |
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Author | Honda, Manami| Iwamuro, Masaya| Tanaka, Takehiro| Yamasaki, Yasushi| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Otsuka, Motoyuki| |
Keywords | colonoscopy esophagogastroduodenoscopy gastrointestinal neoplasms gastrointestinal stromal tumor neurofibromatosis |
Published Date | 2025-04-16 |
Publication Title | JGH Open |
Volume | volume9 |
Issue | issue4 |
Publisher | Wiley |
Start Page | e70151 |
ISSN | 2397-9070 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 40247846 |
DOI | 10.1002/jgh3.70151 |
Web of Science KeyUT | 001468535400001 |
Related Url | isVersionOf https://doi.org/10.1002/jgh3.70151 |
FullText URL | fulltext.pdf |
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Author | Igawa, Shoko| Inokuchi, Toshihiro| Hiraoka, Sakiko| Toyosawa, Junki| Aoyama, Yuki| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahara, Masahiro| Okada, Hiroyuki| Otsuka, Motoyuki| |
Keywords | biologics therapy tacrolimus thiopurine ulcerative colitis |
Published Date | 2025-04-02 |
Publication Title | JGH Open |
Volume | volume9 |
Issue | issue4 |
Publisher | Wiley |
Start Page | e70139 |
ISSN | 2397-9070 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 40177188 |
DOI | 10.1002/jgh3.70139 |
Web of Science KeyUT | 001457389100001 |
Related Url | isVersionOf https://doi.org/10.1002/jgh3.70139 |
FullText URL | fulltext.pdf |
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Author | Aoyama, Yuki| Hiraoka, Sakiko| Yasutomi, Eriko| Inokuchi, Toshihiro| Tanaka, Takehiro| Takei, Kensuke| Igawa, Shoko| Takeuchi, Keiko| Takahara, Masahiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Kato, Jun| Okada, Hiroyuki| Otsuka, Motoyuki| |
Keywords | Ulcerative colitis Leucine-rich alpha 2 glycoprotein Biomarker |
Published Date | 2025-02-12 |
Publication Title | Scientific Reports |
Volume | volume15 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 5248 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025 |
File Version | publisher |
PubMed ID | 39939376 |
DOI | 10.1038/s41598-025-89615-8 |
Web of Science KeyUT | 001421220800034 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-025-89615-8 |
FullText URL | fulltext20250108-02.pdf fig20250108-02.pdf table20250108-02.pdf |
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Author | Toyosawa, Junki| Yamasaki, Yasushi| Aoyama, Yuki| Takei, Kensuke| Igawa, Shoko| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Hiraoka, Sakiko| Okada, Hiroyuki| Otsuka, Motoyuki| |
Keywords | Underwater endoscopic mucosal resection Endoscopic mucosal resection Cold snare polypectomy |
Note | This is the accepted manuscript version of an article published by Karger Publishers in [Junki Toyosawa, Yasushi Yamasaki, Yuki Aoyama, Kensuke Takei, Shoko Igawa, Toshihiro Inokuchi, Hideaki Kinugasa, Masahiro Takahara, Sakiko Hiraoka, Hiroyuki Okada, Motoyuki Otsuka; Adverse Events after Different Endoscopic Resection Procedures for Small and Intermediate-Sized Colorectal Polyps. Dig Dis 2 December 2024; 42 (6): 529–537. https://doi.org/10.1159/000540365] and available on karger.com/Article/FullText/doi.| |
Published Date | 2024-08-09 |
Publication Title | Digestive Diseases |
Volume | volume42 |
Issue | issue6 |
Publisher | S. Karger AG |
Start Page | 529 |
End Page | 537 |
ISSN | 0257-2753 |
NCID | AA10725752 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 S. Karger AG, Basel |
File Version | author |
PubMed ID | 39128468 |
DOI | 10.1159/000540365 |
Web of Science KeyUT | 001374461700001 |
Related Url | isVersionOf https://doi.org/10.1159/000540365 |
Title Alternative | Ulcerative colitis |
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Author | Hiraoka, Sakiko| |
Keywords | 潰瘍性大腸炎 炎症性腸疾患 診断 治療 |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-12-02 |
Volume | volume136 |
Issue | issue3 |
Start Page | 132 |
End Page | 134 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.132 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.132 |
Title Alternative | A case of immune checkpoint inhibitor-associated colitis treated with infliximab |
---|---|
Author | Iwamuro, Masaya| Hiraoka, Sakiko| Otsuka, Motoyuki| |
Abstract | A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary. |
Keywords | インフリキシマブ(infliximab) 免疫関連有害事象(immune-related adverse events) 大腸炎(colitis) |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2024-08-01 |
Volume | volume136 |
Issue | issue2 |
Start Page | 69 |
End Page | 73 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.136.69 |
language | Japanese |
Copyright Holders | Copyright (c) 2024 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.136.69 |
FullText URL | fulltext.pdf |
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Author | Iwamuro, Masaya| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-Ichi| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Motoyuki| |
Keywords | Colonoscopy Esophagogastroduodenoscopy Graft-versus-host disease Hematopoietic stem cell transplantation Intestinal transplant-associated microangiopathy iTAM |
Note | The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-024-03221-y| |
Published Date | 2024-04-22 |
Publication Title | BMC Gastroenterology |
Volume | volume24 |
Issue | issue1 |
Publisher | BMC |
Start Page | 140 |
ISSN | 1471-230X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024. |
File Version | publisher |
PubMed ID | 38649868 |
DOI | 10.1186/s12876-024-03221-y |
Web of Science KeyUT | 001206319800003 |
Related Url | isVersionOf https://doi.org/10.1186/s12876-024-03221-y |
JaLCDOI | 10.18926/AMO/66674 |
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FullText URL | 78_1_079.pdf |
Author | Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Aoyama, Yuki| Yasutomi, Eriko| Igawa, Shoko| Inokuchi, Toshihiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Harada, Keita| Onishi, Hideki| Okada, Hiroyuki| |
Abstract | This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies. |
Keywords | transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore |
Amo Type | Short Communication |
Publication Title | Acta Medica Okayama |
Published Date | 2024-02 |
Volume | volume78 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 79 |
End Page | 83 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38419318 |
Web of Science KeyUT | 001203658200004 |
FullText URL | fulltext.pdf |
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Author | Yamamoto, Shumpei| Kinugasa, Hideaki| Yamasaki, Yasushi| Hirai, Mami| Ako, Soichiro| Takei, Kensuke| Igawa, Shoko| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Inokuchi, Toshihiro| Harada, Keita| Hiraoka, Sakiko| Nouso, Kazuhiro| Tanaka, Takehiro| Okada, Hiroyuki| |
Keywords | colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever |
Published Date | 2021-12-09 |
Publication Title | DEN Open |
Volume | volume2 |
Issue | issue1 |
Publisher | Wiley |
Start Page | e83 |
ISSN | 2692-4609 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Authors. |
File Version | publisher |
PubMed ID | 35310725 |
DOI | 10.1002/deo2.83 |
Web of Science KeyUT | 001047024900091 |
Related Url | isVersionOf https://doi.org/10.1002/deo2.83 |
FullText URL | fulltext.pdf |
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Author | Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Yasutomi, Eriko| Igawa, Shoko| Yamamoto, Shumpei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Harada, Keita| Ohnishi, Hideki| Okada, Hiroyuki| |
Keywords | bowel wall thickness Mayo endoscopic subscore classification transabdominal ultrasonography ulcerative colitis |
Published Date | 2022-09-15 |
Publication Title | Internal Medicine |
Volume | volume61 |
Issue | issue18 |
Publisher | The Japanese Society of Internal Medicine |
Start Page | 2703 |
End Page | 2709 |
ISSN | 0918-2918 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 35185047 |
DOI | 10.2169/internalmedicine.8827-21 |
Web of Science KeyUT | 000857218300001 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.8827-21 |
FullText URL | fulltext.pdf |
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Author | Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Fumio| Okada, Hiroyuki| |
Keywords | central memory T cell flow cytometry natural killer T cells peripheral blood mononuclear cell ulcerative colitis |
Published Date | 2022-01-12 |
Publication Title | International Journal of Immunopathology and Pharmacology |
Volume | volume36 |
Publisher | Sage Publications Inc. |
Start Page | 1 |
End Page | 12 |
ISSN | 0394-6320 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022 |
File Version | publisher |
PubMed ID | 35021918 |
DOI | 10.1177/20587384211051982 |
Web of Science KeyUT | 000747491200001 |
Related Url | isVersionOf https://doi.org/10.1177/20587384211051982 |
FullText URL | fulltext.pdf |
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Author | Yasutomi, Eriko| Inokuchi, Toshihiro| Hiraoka, Sakiko| Takei, Kensuke| Igawa, Shoko| Yamamoto, Shumpei| Ohmori, Masayasu| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Furukawa, Masaki| Itoshima, Kouichi| Okada, Ken| Otsuka, Fumio| Tanaka, Takehiro| Mitsuhashi, Toshiharu| Kato, Jun| Okada, Hiroyuki| |
Published Date | 2021-05-27 |
Publication Title | Scientific Reports |
Volume | volume11 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 11086 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2021 |
File Version | publisher |
PubMed ID | 34045529 |
NAID | 120007089817 |
DOI | 10.1038/s41598-021-90441-x |
Web of Science KeyUT | 000658389400001 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-021-90441-x |
FullText URL | fulltext.pdf |
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Author | Iwamuro, Masaya| Tanaka, Takehiro| Sugihara, Yuusaku| Harada, Keita| Hiraoka, Sakiko| Kondo, Yoshitaka| Okada, Hiroyuki| |
Keywords | endometriosis subepithelial lesion submucosal tumor cecum colonoscopy |
Published Date | 2021 |
Publication Title | Internal Medicine |
Volume | volume60 |
Issue | issue11 |
Publisher | Japanese Society of Internal Medicine |
Start Page | 1697 |
End Page | 1701 |
ISSN | 0918-2918 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 33390498 |
DOI | 10.2169/internalmedicine.6418-20 |
Web of Science KeyUT | 000659353300007 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.6418-20 |
FullText URL | fulltext.pdf |
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Author | Hiraoka, Sakiko| Takashima, Shiho| Inokuchi, Toshihiro| Nakarai, Asuka| Takahara, Masahiro| Harada, Keita| Seki, Yasuhiro| Watanabe, Katsunori| Kato, Jun| Okada, Hiroyuki| |
Keywords | Colitis ulcerative Fecal calprotectin Quantitative fecal immunochemical test Latex agglutination turbidimetric immunoassay Mucosal healing |
Published Date | 2018-12-14 |
Publication Title | Intestinal Research |
Volume | volume17 |
Issue | issue2 |
Publisher | Korean Association for the Study of Intestinal Diseases |
Start Page | 202 |
End Page | 209 |
ISSN | 1598-9100 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Copyright 2019. Korean Association for the Study of Intestinal Diseases |
File Version | publisher |
PubMed ID | 30541228 |
DOI | 10.5217/ir.2018.00086 |
Web of Science KeyUT | 000466136800006 |
Related Url | isVersionOf https://doi.org/10.5217/ir.2018.00086 |
FullText URL | fulltext.pdf |
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Author | Sugihara, Yuusaku| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Morito, Yuki| Takahashi, Sakuma| Harada, Keita| Tanaka, Takehiro| Otsuka, Fumio| Okada, Hiroyuki| |
Keywords | graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy |
Published Date | 2020-02-21 |
Publication Title | Experimental and Therapeutic Medicine |
Volume | volume19 |
Issue | issue4 |
Publisher | Spandidos Publications |
Start Page | 3076 |
End Page | 3080 |
ISSN | 1792-0981 |
NCID | AA12610820 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Sugiharaet al. |
File Version | publisher |
PubMed ID | 32256795 |
DOI | 10.3892/etm.2020.8538 |
Web of Science KeyUT | 000523637100082 |
Related Url | isVersionOf https://doi.org/10.3892/etm.2020.8538 |
FullText URL | fulltext.pdf |
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Author | Iwamuro, Masaya| Tanaka, Takehiro| Yamauchi, Nao| Nakashima, Yuri| Wada, Takahira| Hiraoka, Sakiko| Kawahara, Yoshiro| Okada, Hiroyuki| |
Keywords | cytomegalovirus colitis pseudolipomatosis gastric emphysema post-resuscitation diabetes mellitus |
Published Date | 2020-02-15 |
Publication Title | Internal Medicine |
Volume | volume59 |
Issue | issue4 |
Publisher | The Japanese Society of Internal Medicine |
Start Page | 519 |
End Page | 525 |
ISSN | 0918-2918 |
NCID | AA10827774 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 31645533 |
NAID | 130007798412 |
DOI | 10.2169/internalmedicine.3633-19 |
Web of Science KeyUT | 000516549400009 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.3633-19 |
FullText URL | fulltext.pdf |
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Author | Kinugasa, Hideaki| Hiraoka, Sakiko| Nouso, Kazuhiro| Yamamoto, Shumpei| Hirai, Mami| Terasawa, Hiroyuki| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Harada, Keita| Tanaka, Takehiro| Okada, Hiroyuki| |
Keywords | IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA |
Published Date | 2020-12-03 |
Publication Title | BMC Cancer |
Volume | volume20 |
Issue | issue1 |
Publisher | BMC |
Start Page | 1188 |
ISSN | 1471-2407 |
NCID | AA12034763 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2020 |
File Version | publisher |
PubMed ID | 33272240 |
DOI | 10.1186/s12885-020-07699-z |
Web of Science KeyUT | 000597268700004 |
Related Url | isVersionOf https://doi.org/10.1186/s12885-020-07699-z |
FullText URL | fulltext.pdf |
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Author | Iwamuro, Masaya| Takahashi, Takahide| Tanaka, Takehiro| Toji, Tomohiro| Hiraoka, Sakiko| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
Published Date | 2020-10-07 |
Publication Title | Case Reports in Gastrointestinal Medicine |
Volume | volume2020 |
Publisher | Hindawi |
Start Page | 8893604 |
ISSN | 2090-6528 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Masaya Iwamuro et al. |
File Version | publisher |
PubMed ID | 33083067 |
DOI | 10.1155/2020/8893604 |
Web of Science KeyUT | 000583201400001 |
Related Url | isVersionOf https://doi.org/10.1155/2020/8893604 |
JaLCDOI | 10.18926/AMO/60363 |
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FullText URL | 74_4_265.pdf |
Author | Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun| |
Abstract | Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy. |
Keywords | Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 265 |
End Page | 274 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843757 |
Web of Science KeyUT | 000562508700001 |
NAID | 120006880202 |
FullText URL | fulltext.pdf |
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Author | Yasutomi, Eriko| Hiraoka, Sakiko| Yamamoto, Shumpei| Oka, Shohei| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Harada, Keita| Kato, Jun| Okada, Hiroyuki| |
Keywords | ulcerative colitis salicylates mesalazine sulfasalazine |
Published Date | 2019-12-02 |
Publication Title | Journal of Clinical Medicine |
Volume | volume8 |
Issue | issue12 |
Publisher | MDPI |
ISSN | 2077-0383 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2019 by the authors. |
File Version | publisher |
PubMed ID | 31810227 |
DOI | 10.3390/jcm8122109 |
Web of Science KeyUT | 000506640400082 |
Related Url | isVersionOf https://doi.org/10.3390/jcm8122109 |