Higuchi, Takahiro - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Redefining AT1 Receptor PET Imaging: Introducing the Radiotracer [18F]DR29

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Author	Chen, Xinyu\| Kimura, Hiroyuki\| Sasaki, Takanori\| Klimek, Konrad\| Mühlig, Saskia\| Arias-Loza, Anahi Paula\| Nose, Naoko\| Yagi, Yusuke\| Rowe, Steven P\| Lapa, Constantin\| Werner, Rudolf A.\| Higuchi, Takahiro\|
Keywords	angiotensin II type 1 receptor organic anion transporters organic anion transporting polypeptides renal imaging renin-angiotensin system
Published Date	2025-10
Publication Title	Hypertension
Volume	volume82
Issue	issue10
Publisher	Ovid Technologies (Wolters Kluwer Health)
Start Page	1626
End Page	1637
ISSN	0194-911X
NCID	AA00214236
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Authors.
File Version	publisher
PubMed ID	40776860
DOI	10.1161/hypertensionaha.124.24441
Web of Science KeyUT	001572715100018
Related Url	isVersionOf https://doi.org/10.1161/hypertensionaha.124.24441

Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles

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Author	Schorr, Kathrin\| Chen, Xinyu\| Sasaki, Takanori\| Arias-Loza, Anahi Paula\| Lang, Johannes\| Higuchi, Takahiro\| Goepferich, Achim\|
Keywords	polymer nanoparticles direct 99mTc-labeling single-photon emission computed tomography radio-thin layer chromatography radiocolloids
Published Date	2024-08-30
Publication Title	ACS Pharmacology & Translational Science
Volume	volume7
Issue	issue9
Publisher	American Chemical Society (ACS)
Start Page	2604
End Page	2611
ISSN	2575-9108
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
PubMed ID	39296255
DOI	10.1021/acsptsci.4c00383
Web of Science KeyUT	001302850400001
Related Url	isVersionOf https://doi.org/10.1021/acsptsci.4c00383

Evaluating the Patterns of FAPI Uptake in the Shoulder Joint: a Preliminary Study Comparing with FDG Uptake in Oncological Studies

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Author	Matsusaka, Yohji\| Werner, Rudolf A.\| Serfling, Sebastian E.\| Buck, Andreas K.\| Kosmala, Aleksander\| Sasaki, Takanori\| Weich, Alexander\| Higuchi, Takahiro\|
Keywords	Fibroblast activation inhibitor Shoulder Acromioclavicular joints F-18 fluorodeoxyglucose Positron emission tomography FAP Ga-68 FAPI-04 Rheumatoid arthritis Osteoarthritis
Published Date	2024-01-04
Publication Title	Molecular Imaging and Biology
Volume	volume26
Issue	issue2
Publisher	Springer Science and Business Media LLC
Start Page	294
End Page	300
ISSN	1536-1632
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
PubMed ID	38177615
DOI	10.1007/s11307-023-01893-8
Web of Science KeyUT	001136274500001
Related Url	isVersionOf https://doi.org/10.1007/s11307-023-01893-8

Investigating the fate of Zirconium-89 labelled antibody in cynomolgus macaques

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Author	Sasaki, Takanori\| Kimura, Sadaaki\| Noda, Akihiro\| Murakami, Yoshihiro\| Miyoshi, Sosuke\| Akehi, Masaru\| Ochiai, Kazuhiko\| Watanabe, Masami\| Higuchi, Takahiro\| Matsuura, Eiji\|
Keywords	PET imaging Zirconium-89 Therapeutic antibodies Non-human primates
Published Date	2025-05
Publication Title	Nuclear Medicine and Biology
Volume	volume144-145
Publisher	Elsevier BV
Start Page	109001
ISSN	0969-8051
NCID	AA10864894
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Authors.
File Version	publisher
PubMed ID	39985867
DOI	10.1016/j.nucmedbio.2025.109001
Web of Science KeyUT	001432539500001
Related Url	isVersionOf https://doi.org/10.1016/j.nucmedbio.2025.109001

Nomogram models for predicting outcomes in thyroid cancer patients with distant metastasis receiving 131iodine therapy

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Author	Jin, Shui\| Ye, Xuemei\| Ye, Ting\| Chen, Xinyu\| Ji, Jianfeng\| Wang, Jinyu\| Zhu, Xin\| Mao, Xiaochun\| Higuchi, Takahiro\| Yi, Heqing\|
Keywords	131iodine Activity Distant metastasis Iodine radioisotopes Thyroid cancer
Published Date	2025-01-20
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	2486
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	39833265
DOI	10.1038/s41598-025-86169-7
Web of Science KeyUT	001401998100012
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-86169-7

In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging

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Author	Saito, Yukihiro\| Nose, Naoko\| Iida, Toshihiro\| Akazawa, Kaoru\| Kanno, Takayuki\| Fujimoto, Yuki\| Sasaki, Takanori\| Akehi, Masaru\| Higuchi, Takahiro\| Akagi, Satoshi\| Yoshida, Masashi\| Miyoshi, Toru\| Ito, Hiroshi\| Nakamura, Kazufumi\|
Keywords	sodium/iodide symporter human induced pluripotent stem cell-derived cardiomyocytes single photon emission computed tomography cell-based therapy in vivo imaging
Published Date	2023-09-07
Publication Title	Frontiers in Cardiovascular Medicine
Volume	volume10
Publisher	Frontiers Media
Start Page	1261330
ISSN	2297-055X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 Saito, Nose, Iida, Akazawa, Kanno, Fujimoto, Sasaki, Akehi, Higuchi, Akagi, Yoshida, Miyoshi, Ito and Nakamura.
File Version	publisher
PubMed ID	37745108
DOI	10.3389/fcvm.2023.1261330
Web of Science KeyUT	001069842100001
Related Url	isVersionOf https://doi.org/10.3389/fcvm.2023.1261330

Rationalizing the Binding Modes of PET Radiotracers Targeting the Norepinephrine Transporter

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Author	Tutov, Anna\| Chen, Xinyu\| Werner, Rudolf A.\| Muehlig, Saskia\| Zimmermann, Thomas\| Nose, Naoko\| Koshino, Kazuhiro\| Lapa, Constantin\| Decker, Michael\| Higuchi, Takahiro\|
Keywords	positron emission tomography norepinephrine transporter sympathetic nervous system structure-activity relationships T-shaped π–π stacking
Published Date	2023-02-17
Publication Title	Pharmaceutics
Volume	volume15
Issue	issue2
Publisher	MDPI
Start Page	690
ISSN	1999-4923
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 by the authors.
File Version	publisher
PubMed ID	36840011
DOI	10.3390/pharmaceutics15020690
Web of Science KeyUT	000941716700001
Related Url	isVersionOf https://doi.org/10.3390/pharmaceutics15020690

Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals

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Author	Matsusaka, Yohji\| Werner, Rudolf A.\| Arias-Loza, Paula\| Nose, Naoko\| Sasaki, Takanori\| Chen, Xinyu\| Lapa, Constantin\| Higuchi, Takahiro\|
Published Date	2022-07-16
Publication Title	Molecular Imaging
Volume	volume2022
Publisher	Hindawi Ltd.
Start Page	9810097
ISSN	1536-0121
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Yohji Matsusaka et al.
File Version	publisher
PubMed ID	35903250
DOI	10.1155/2022/9810097
Web of Science KeyUT	000887057400001
Related Url	isVersionOf https://doi.org/10.1155/2022/9810097

In Vivo Functional Assessment of Sodium-Glucose Cotransporters (SGLTs) Using [F-18]Me4FDG PET in Rats

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Author	Matsusaka, Yohji\| Chen, Xinyu\| Arias-Loza, Paula\| Werner, Rudolf A.\| Nose, Naoko\| Sasaki, Takanori\| Rowe, Steven P.\| Pomper, Martin G.\| Lapa, Constantin\| Higuchi, Takahiro\|
Published Date	2022-06-21
Publication Title	Molecular Imaging
Volume	volume2022
Publisher	Hindawi Ltd.
Start Page	4635171
ISSN	1536-0121
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Yohji Matsusaka et al.
File Version	publisher
PubMed ID	35903251
DOI	10.1155/2022/4635171
Web of Science KeyUT	000890332200001
Related Url	isVersionOf https://doi.org/10.1155/2022/4635171

Generative adversarial network-created brain SPECTs of cerebral ischemia are indistinguishable to scans from real patients

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Author	Werner, Rudolf A.\| Higuchi, Takahiro\| Nose, Naoko\| Toriumi, Fujio\| Matsusaka, Yohji\| Kuji, Ichiei\| Kazuhiro, Koshino\|
Published Date	2022-11-05
Publication Title	Scientific Reports
Volume	volume12
Issue	issue1
Publisher	Nature Portfolio
Start Page	18787
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022
File Version	publisher
PubMed ID	36335166
DOI	10.1038/s41598-022-23325-3
Web of Science KeyUT	000879722100016
Related Url	isVersionOf https://doi.org/10.1038/s41598-022-23325-3

The Number of Frames on ECG-Gated F-18-FDG Small Animal PET Has a Significant Impact on LV Systolic and Diastolic Functional Parameters

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Author	Eissler, Christoph\| Werner, Rudolf A.\| Arias-Loza, Paula\| Nose, Naoko\| Chen, Xinyu\| Pomper, Martin G.\| Rowe, Steven P.\| Lapa, Constantin\| Buck, Andreas K.\| Higuchi, Takahiro\|
Published Date	2021-12-06
Publication Title	Molecular Imaging
Volume	volume2021
Publisher	Hindawi Ltd.
Start Page	4629459
ISSN	1536-0121
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Christoph Eissler et al.
File Version	publisher
PubMed ID	34987313
DOI	10.1155/2021/4629459
Web of Science KeyUT	000741997000001
Related Url	isVersionOf https://doi.org/10.1155/2021/4629459

[18F]FDG-labelled stem cell PET imaging in different route of administrations and multiple animal species

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Author	Nose, Naoko\| Nogami, Suguru\| Koshino, Kazuhiro\| Chen, Xinyu\| Werner, Rudolf A.\| Kashima, Soki\| Rowe, Steven P.\| Lapa, Constantin\| Fukuchi, Kazuki\| Higuchi, Takahiro\|
Published Date	2021-05-25
Publication Title	Scientific Reports
Volume	volume11
Issue	issue1
Publisher	NATURE RESEARCH
Start Page	10896
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	34035416
DOI	10.1038/s41598-021-90383-4
NAID	120007098536
Web of Science KeyUT	000659135700025
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-90383-4

Current and future perspectives on functional molecular imaging in nephro-urology: theranostics on the horizon

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Author	Toyama, Yoshitaka\| Werner, Rudolf A.\| Ruiz-Bedoya, Camilo A.\| Ordonez, Alvaro A.\| Takase, Kei\| Lapa, Constantin\| Jain, Sanjay K.\| Pomper, Martin G.\| Rowe, Steven P.\| Higuchi, Takahiro\|
Keywords	Glomerular filtration rate renal kidney renal function positron emission tomography nephrology urology molecular imaging theranostics
Note	This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.\|
Published Date	2021-04-07
Publication Title	Theranostics
Volume	volume11
Issue	issue12
Publisher	Ivyspring Int Publ
Start Page	6105
End Page	6119
ISSN	1838-7640
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The author(s).
File Version	publisher
PubMed ID	33897902
DOI	10.7150/thno.58682
NAID	120007037373
Web of Science KeyUT	000642591000007
Related Url	isVersionOf https://doi.org/10.7150/thno.58682

The next era of renal radionuclide imaging: novel PET radiotracers

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Author	Werner, Rudolf A.\| Chen, Xinyu\| Lapa, Constantin\| Koshino, Kazuhiro\| Rowe, Steven P.\| Pomper, Martin G.\| Javadi, Mehrbod S.\| Higuchi, Takahiro\|
Keywords	Kidney Positron emission tomography PET [18F]Fluorodeoxysorbitol GFR ERPF
Published Date	2019-05-30
Publication Title	European Journal of Nuclear Medicine and Molecular Imaging
Volume	volume46
Issue	issue9
Publisher	Springer
Start Page	1773
End Page	1786
ISSN	1619-7070
NCID	AA1161516X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
PubMed ID	31144061
DOI	10.1007/s00259-019-04359-8
Web of Science KeyUT	000475673300003
Related Url	isVersionOf https://doi.org/10.1007/s00259-019-04359-8

Initial Evaluation of AF78: a Rationally Designed Fluorine-18-Labelled PET Radiotracer Targeting Norepinephrine Transporter

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Author	Chen, Xinyu\| Fritz, Alexander\| Werner, Rudolf A.\| Nose, Naoko\| Yagi, Yusuke\| Kimura, Hiroyuki\| Rowe, Steven P.\| Koshino, Kazuhiro\| Decker, Michael\| Higuchi, Takahiro\|
Keywords	Norepinephrine transporter Positron emission tomography Phenethylguanidine [18F]AF78
Published Date	2019-07-22
Publication Title	Molecular Imaging and Biology
Volume	volume22
Issue	issue3
Publisher	Springer
Start Page	602
End Page	611
ISSN	1536-1632
NCID	AA1170000X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Authors
File Version	publisher
PubMed ID	31332629
DOI	10.1007/s11307-019-01407-5
Web of Science KeyUT	000535707700015
Related Url	isVersionOf https://doi.org/10.1007/s11307-019-01407-5

Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements

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Author	Chen, Xinyu\| Kudo, Takashi\| Lapa, Constantin\| Buck, Andreas\| Higuchi, Takahiro\|
Keywords	Norepinephrine transporter Benzylguanidine Phenethylguanidine Antidepressant Organic cation transporter
Published Date	2020-04-09
Publication Title	Journal of Neural Transmission
Volume	volume127
Issue	issue6
Publisher	Springer
Start Page	851
End Page	873
ISSN	0300-9564
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	Author(s)
File Version	author
PubMed ID	32274584
DOI	10.1007/s00702-020-02180-4
Web of Science KeyUT	000535371000001
Related Url	isVersionOf https://doi.org/10.1007/s00702-020-02180-4

Capabilities of multi-pinhole SPECT with two stationary detectors for in vivo rat imaging

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Author	Janssen, Jan P.\| Hoffmann, Jan V.\| Kanno, Takayuki\| Nose, Naoko\| Grunz, Jan-Peter\| Onoguchi, Masahisa\| Chen, Xinyu\| Lapa, Constantin\| Buck, Andreas K.\| Higuchi, Takahiro\|
Keywords	Biomarkers Diagnostic markers Medical research Preclinical research Translational research
Published Date	2020-10-29
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature Research
Start Page	18616
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	33122774
DOI	10.1038/s41598-020-75696-0
Web of Science KeyUT	000587692300013
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-75696-0

Performance evaluation of fifth-generation ultra-high-resolution SPECT system with two stationary detectors and multi-pinhole imaging

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Author	Hoffmann, Jan, V\| Janssen, Jan P.\| Kanno, Takayuki\| Shibutani, Takayuki\| Onoguchi, Masahisa\| Lapa, Constantin\| Grunz, Jan-Peter\| Buck, Andreas K.\| Higuchi, Takahiro\|
Keywords	Small-animal imaging SPECT Mouse Collimator Post-reconstruction filtering
Published Date	2020-11-02
Publication Title	EJNMMI Physics
Volume	volume7
Issue	issue1
Publisher	Springer
Start Page	64
ISSN	2197-7364
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s). 2020
File Version	publisher
PubMed ID	33140263
DOI	10.1186/s40658-020-00335-6
Web of Science KeyUT	000584467200001
Related Url	isVersionOf https://doi.org/10.1186/s40658-020-00335-6

Cytotoxic T Lymphocytes Regenerated from iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model

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Author	Kashima, Soki\| Maeda, Takuya\| Masuda, Kyoko\| Nagano, Seiji\| Inoue, Takamitsu\| Takeda, Masashi\| Kono, Yuka\| Kobayashi, Takashi\| Saito, Shigeyoshi\| Higuchi, Takahiro\| Ichise, Hiroshi\| Kobayashi, Yuka\| Iwaisako, Keiko\| Terada, Koji\| Agata, Yasutoshi\| Numakura, Kazuyuki\| Saito, Mitsuru\| Narita, Shintaro\| Yasukawa, Masaki\| Ogawa, Osamu\| Habuchi, Tomonori\| Kawamoto, Hiroshi\|
Keywords	Cancer Cellular Therapy Immunological Methods
Published Date	2020-04-24
Publication Title	iScience
Volume	volume23
Issue	issue4
Publisher	Cell Press
Start Page	100998
ISSN	25890042
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
PubMed ID	32259478
DOI	10.1016/j.isci.2020.100998
Web of Science KeyUT	000528359400030
Related Url	isVersionOf https://doi.org/10.1016/j.isci.2020.100998

Ventricular Distribution Pattern of the Novel Sympathetic Nerve PET Radiotracer F-18-LMI1195 in Rabbit Hearts

FullText URL	SR9_1_170269.pdf
Author	Werner, Rudolf A.\| Wakabayashi, Hiroshi\| Chen, Xinyu\| Hayakawa, Nobuyuki\| Lapa, Constantin\| Rowe, Steven P.\| Javadi, Mehrbod S.\| Robinson, Simon\| Higuchi, Takahiro\|
Published Date	2019-11-19
Publication Title	Scientific Reports
Volume	volume9
Publisher	Nature Publishing Group
Start Page	17026
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Te Author(s) 2019
File Version	publisher
PubMed ID	31745188
DOI	10.1038/s41598-019-53596-2
Web of Science KeyUT	000497701200014
Related Url	isVersionOf https://doi.org/10.1038/s41598-019-53596-2