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ID 67630
Author
Tokushige, Keisuke Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kobori, Yuito Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Asai, Shota School of Pharmacy, Shujitsu University
Abe, Takumi Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University ORCID Kaken ID researchmap
Abstract
2-Aminobenzoyl chlorides possess both a nucleophilic nitrogen atom and an electrophilic carbonyl group, and thus selective acylation of nucleophiles is challenging; self-dimerization and sluggish reactions occur. Herein, we introduce a new synthetic protocol using 2-aminobenzoyl surrogates, allowing concise entry to decorated 2-aminobenzoyl derivatives in the absence of transition metals, acid chlorides, and specific reagents.
Note
This is an Accepted Manuscript of an article published by Royal Society of Chemistry (RSC).
This fulltext file will be available in Aug. 2025.
Published Date
2024
Publication Title
Organic and Biomolecular Chemistry
Volume
volume22
Issue
issue36
Publisher
Royal Society of Chemistry (RSC)
Start Page
7343
End Page
7348
ISSN
1477-0520
NCID
AA1168650X
Content Type
Journal Article
language
English
OAI-PMH Set
岡山大学
Copyright Holders
© The Royal Society of Chemistry 2024
File Version
author
PubMed ID
DOI
Web of Science KeyUT
Related Url
isVersionOf https://doi.org/10.1039/d4ob01218f
Funder Name
Japan Society for the Promotion of Science
Japan Science and Technology Agency
助成番号
22K06503
JPMJSP2126