| ID | 66495 |
| FullText URL | |
| Author |
Kimata, Momoko
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Abe, Takumi
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
researchmap
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| Abstract | The first total synthesis of the proposed structure of unprecedented indolyl derivative bearing 1,2-propanediol moiety is described. Isomerization of 3-alkoxyindolines through indolenium intermediates was the key step in the total synthesis. H-1, C-13-NMR, IR, and HRMS spectra of the synthetic compound drastically differed to those of the originally reported structure, which suggests the natural product requires revision.
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| Keywords | 1-(1H-indol-3-yloxy)propan-2-ol
indole alkaloid
isomerization
silver
umpolung
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| Published Date | 2023-12-12
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| Publication Title |
Chemistry
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| Volume | volume5
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| Issue | issue4
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| Publisher | MDPI
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| Start Page | 2772
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| End Page | 2784
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| ISSN | 2624-8549
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| Content Type |
Journal Article
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| language |
English
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| OAI-PMH Set |
岡山大学
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| Copyright Holders | © 2023 by the authors.
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| File Version | publisher
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| DOI | |
| Web of Science KeyUT | |
| Related Url | isVersionOf https://doi.org/10.3390/chemistry5040177
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| License | https://creativecommons.org/licenses/by/4.0/
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| Citation | Kimata, M.; Abe, T. Total Synthesis of the Proposed Structure of Indolyl 1,2-Propanediol Alkaloid, 1-(1H-Indol-3-yloxy)propan-2-ol. Chemistry 2023, 5, 2772-2784. https://doi.org/10.3390/chemistry5040177
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| Funder Name |
Japan Society for the Promotion of Science
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| 助成番号 | 22K06503
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