| ID | 62273 |
| FullText URL | |
| Author |
Matsumoto, Namiko
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Hishikawa, Nozomi
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
Ikegami, Ken
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Sato, Kota
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Omote, Yoshio
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Takemoto, Mami
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
Yamashita, Tom
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Taniguchi, Kohei
Departments of Pathology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Abe, Koji
Departments of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
publons
researchmap
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| Abstract | We herein report a 75-year-old man who developed disturbed consciousness with polynuclear cell dominant pleocytosis and low glucose and extremely high interleukin (IL)-6 levels in his cerebrospinal fluid. The biopsy specimen from his right supraclavicular lymph node showed the infiltration of inflammatory cells positive for IgG, IgG4 and IL-6. Prednisolone and azathioprine administered under suspicion of IgG4-related disease (IgG4-RD) or multicentric Castleman's disease (MCD) successfully remitted the symptoms. However, he developed myelodysplastic syndrome (MDS) and died 18 months later. The extremely high IL-6 may have been related to the rare neurological manifestations and development of MDS in the present case.
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| Keywords | encephalopathy
IgG4 related disease
interleukin-6
multicentric Castleman's disease
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| Published Date | 2021-07-01
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| Publication Title |
Internal Medicine
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| Volume | volume60
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| Issue | issue13
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| Publisher | The Japanese Society of Internal Medicine
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| Start Page | 2125
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| End Page | 2128
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| ISSN | 0918-2918
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| Content Type |
Journal Article
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| language |
English
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| OAI-PMH Set |
岡山大学
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| Copyright Holders | © 2021 The Japanese Society of Internal Medicine
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| File Version | publisher
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| PubMed ID | |
| DOI | |
| Web of Science KeyUT | |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.6098-20
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| License | https://creativecommons.org/licenses/by-nc-nd/4.0/
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